Details for: Ebf1

Gene ID: 13591

Symbol: Ebf1

Ensembl ID: ENSMUSG00000057098

Description: early B cell factor 1

Associated with

  • C2h2 zinc finger domain binding
    (GO:0070742)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Metal ion binding
    (GO:0046872)
  • Multicellular organism development
    (GO:0007275)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 2664873231

Symbol: COE1_MOUSE

Name: Transcription factor COE1

UniProtKB Accession Codes:

Q07802

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 3 GeneTree 1 Genevisible 1 GlyGen 1 InParanoid 1 InterPro 9 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 3 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 8491377

Title: Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression.

PubMed ID: 8491377

DOI: 10.1101/gad.7.5.760

PubMed ID: 8497258

Title: Purification of early-B-cell factor and characterization of its DNA-binding specificity.

PubMed ID: 8497258

DOI: 10.1128/mcb.13.6.3392-3400.1993

PubMed ID: 1915300

Title: A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation.

PubMed ID: 1915300

DOI: 10.1002/j.1460-2075.1991.tb04905.x

PubMed ID: 7542362

Title: Failure of B-cell differentiation in mice lacking the transcription factor EBF.

PubMed ID: 7542362

DOI: 10.1038/376263a0

PubMed ID: 9151732

Title: The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.

PubMed ID: 9151732

DOI: 10.1523/jneurosci.17-11-04149.1997

PubMed ID: 20876732

Title: Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins.

PubMed ID: 20876732

DOI: 10.1101/gad.1976610

PubMed ID: 20451411

Title: Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.

PubMed ID: 20451411

DOI: 10.1016/j.immuni.2010.04.013

PubMed ID: 23812095

Title: Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells.

PubMed ID: 23812095

DOI: 10.1038/ni.2641

PubMed ID: 32130892

Title: Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes.

PubMed ID: 32130892

DOI: 10.1016/j.celrep.2020.02.023

Sequence Information:

  • Length: 591
  • Mass: 64464
  • Checksum: E47797B6FC1E5071
  • Sequence:
    • MFGIQESIQR SGSSMKEEPL GSGMNAVRTW MQGAGVLDAN TAAQSGVGLA RAHFEKQPPS 
NLRKSNFFHF VLALYDRQGQ PVEIERTAFV GFVEKEKEAN SEKTNNGIHY RLQLLYSNGI 
RTEQDFYVRL IDSMTKQAIV YEGQDKNPEM CRVLLTHEIM CSRCCDKKSC GNRNETPSDP 
VIIDRFFLKF FLKCNQNCLK NAGNPRDMRR FQVVVSTTVN VDGHVLAVSD NMFVHNNSKH 
GRRARRLDPS EGTPSYLEHA TPCIKAISPS EGWTTGGATV IIIGDNFFDG LQVIFGTMLV 
WSELITPHAI RVQTPPRHIP GVVEVTLSYK SKQFCKGTPG RFIYTALNEP TIDYGFQRLQ 
KVIPRHPGDP ERLPKEVILK RAADLVEALY GMPHNNQEII LKRAADIAEA LYSVPRNHNQ 
LPALANTSVH AGMMGVNSFS GQLAVNVSEA SQATNQGFTR NSSSVSPHGY VPSTTPQQTN 
YNSVTTSMNG YGSAAMSNLG GSPTFLNGSA ANSPYAIVPS SPTMASSTSL PSNCSSSSGI 
FSFSPANMVS AVKQKSAFAP VVRPQTSPPP TCTSTNGNSL QAISGMIVPP M

Genular Protein ID: 3936624379

Symbol: Q8CBL7_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8CBL7

Database IDs:

AGR 1 ARBA 10 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 InterPro 9 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 3 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 578
  • Mass: 63042
  • Checksum: 697AD1AA1208B31C
  • Sequence:
    • SMKEEPLGSG MNAVRTWMQG AGVLDANTAA QSGVGLARAH FEKQPPSNLR KSNFFHFVLA 
LYDRQGQPVE IERTAFVGFV EKEKEANSEK TNNGIHYRLQ LLYSNGIRTE QDFYVRLIDS 
MTKQAIVYEG QDKNPEMCRV LLTHEIMCSR CCDKKSCGNR NETPSDPVII DRFFLKFFLK 
CNQNCLKNAG NPRDMRRFQV VVSTTVNVDG HVLAVSDNMF VHNNSKHGRR ARRLDPSEGT 
PSYLEHATPC IKAISPSEGW TTGGATVIII GDNFFDGLQV IFGTMLVWSE LITPHAIRVQ 
TPPRHIPGVV EVTLSYKSKQ FCKGTPGRFI YTALNEPTID YGFQRLQKVI PRHPGDPERL 
PKEVILKRAA DLVEALYGMP HNNQEIILKR AADIAEALYS VPRNHNQLPA LANTSVHAGM 
MGVNSFSGQL AVNVSEASQA TNQGFTRNSS SVSPHGYVPS TTPQQTNYNS VTTSMNGYGS 
AAMSNLGGSP TFLNGSAANS PYAIVPSSPT MASSTSLPSN CSSSSGIFSF SPANMVSAVK 
QKSAFAPVVR PQTSPPPTCT STNGNSLQAI SGMIVPPM

Genular Protein ID: 4163172208

Symbol: Q5SWK4_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q5SWK4

Database IDs:

AGR 1 ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 3 GeneTree 1 InterPro 9 KEGG 1 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 4 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 592
  • Mass: 64535
  • Checksum: 6A95ED03B5B349DD
  • Sequence:
    • MFGIQESIQR SGSSMKEEPL GSGMNAVRTW MQGAGVLDAN TAAQSGVGLA RAHFEKQPPS 
NLRKSNFFHF VLALYDRQGQ PVEIERTAFV GFVEKEKEAN SEKTNNGIHY RLQLLYSNGI 
RTEQDFYVRL IDSMTKQAIV YEGQDKNPEM CRVLLTHEIM CSRCCDKKSC GNRNETPSDP 
VIIDRFFLKF FLKCNQNCLK NAGNPRDMRR FQVVVSTTVN VDGHVLAVSD NMFVHNNSKH 
GRRARRLDPS EGTPSYLEHA ATPCIKAISP SEGWTTGGAT VIIIGDNFFD GLQVIFGTML 
VWSELITPHA IRVQTPPRHI PGVVEVTLSY KSKQFCKGTP GRFIYTALNE PTIDYGFQRL 
QKVIPRHPGD PERLPKEVIL KRAADLVEAL YGMPHNNQEI ILKRAADIAE ALYSVPRNHN 
QLPALANTSV HAGMMGVNSF SGQLAVNVSE ASQATNQGFT RNSSSVSPHG YVPSTTPQQT 
NYNSVTTSMN GYGSAAMSNL GGSPTFLNGS AANSPYAIVP SSPTMASSTS LPSNCSSSSG 
IFSFSPANMV SAVKQKSAFA PVVRPQTSPP PTCTSTNGNS LQAISGMIVP PM

Genular Protein ID: 1282706288

Symbol: Q3UTW6_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UTW6

Database IDs:

AGR 1 ARBA 10 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 InterPro 9 MGI 2 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 Pfam 3 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 523
  • Mass: 57491
  • Checksum: FCCDAC89401841DC
  • Sequence:
    • MFGIQESIQR SGSSMKEEPL GSGMNAVRTW MQGAGVLDAN TAAQSGVGLA RAHFEKQPPS 
NLRKSNFFHF VLALYDRQGQ PVEIERTAFV GFVEKEKEAN SEKTNNGIHY RLQLLYSNGI 
RTEQDFYVRL IDSMTKQAIV YEGQDKNPEM CRVLLTHEIM CSRCCDKKSC GNRNETPSDP 
VIIDRFFLKF FLKCNQNCLK NAGNPRDMRR FQVVVSTTVN VDGHVLAVSD NMFVHNNSKH 
GRRARRLDPS EATPCIKAIS PSEGWTTGGA TVIIIGDNFF DGLQVIFGTM LVWSELITPH 
AIRVQTPPRH IPGVVEVTLS YKSKQFCKGT PGRFIYTALN EPTIDYGFQR LQKVIPRHPG 
DPERLPKEVI LKRAADLVEA LYGMPHNNQE IILKRAADIA EALYSVPRNH NQLPALANTS 
VHAGMMGVNS FSGQLAVNVS EASQATNQVV PSSPTMASST SLPSNCSSSS GIFSFSPANM 
VSAVKQKSAF APVVRPQTSP PPTCTSTNGN SLQAISGMIV PPM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.