Details for: Ebf2

Gene ID: 13592

Symbol: Ebf2

Ensembl ID: ENSMUSG00000022053

Description: early B cell factor 2

Associated with

  • Adipose tissue development
    (GO:0060612)
  • Brown fat cell differentiation
    (GO:0050873)
  • Cell fate determination
    (GO:0001709)
  • Chromatin binding
    (GO:0003682)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Metal ion binding
    (GO:0046872)
  • Multicellular organism development
    (GO:0007275)
  • Nucleus
    (GO:0005634)
  • Positive regulation of chromatin binding
    (GO:0035563)
  • Positive regulation of cold-induced thermogenesis
    (GO:0120162)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 1293018548

Symbol: COE2_MOUSE

Name: Transcription factor COE2

UniProtKB Accession Codes:

O08792 Q543D5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 3 GO 14 Gene3D 3 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 3 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 9211912

Title: Mmot1, a new helix-loop-helix transcription factor gene displaying a sharp expression boundary in the embryonic mouse brain.

PubMed ID: 9211912

DOI: 10.1074/jbc.272.28.17632

PubMed ID: 9151732

Title: The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.

PubMed ID: 9151732

DOI: 10.1523/jneurosci.17-11-04149.1997

PubMed ID: 9389446

Title: Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.

PubMed ID: 9389446

DOI: 10.1002/(sici)1097-0177(199711)210:3<191::aid-aja1>3.0.co;2-b

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16326388

Title: EBF2 regulates osteoblast-dependent differentiation of osteoclasts.

PubMed ID: 16326388

DOI: 10.1016/j.devcel.2005.10.009

PubMed ID: 27923061

Title: Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis.

PubMed ID: 27923061

DOI: 10.1371/journal.pgen.1006474

Sequence Information:

  • Length: 575
  • Mass: 62606
  • Checksum: E8CDD6DAC7637449
  • Sequence:
    • MFGIQDTLGR GPALKDKSLG AEMDSVRSWV RNVGVVDANV AAQSGVALSR AHFEKQPPSN 
LRKSNFFHFV LALYDRQGQP VEIERTAFVD FVENDKEQGN EKTNNGTHYK LQLLYSNGVR 
TEQDLYVRLI DSVTKQPIAY EGQNKNPEMC RVLLTHEVMC SRCCEKKSCG NRNETPSDPV 
IIDRFFLKFF LKCNQNCLKT AGNPRDMRRF QVVLSTTVNV DGHVLAVSDN MFVHNNSKHG 
RRARRLDPSE ATPCIKAISP SEGWTTGGAM VIIIGDNFFD GLQVVFGTML VWSELITPHA 
IRVQTPPRHI PGVVEVTLSY KSKQFCKGAP GRFIYTALNE PTIDYGFQRL QKVIPRHPGD 
PERLAKEMLL KRAADLVEAL YGTPHNNQDI ILKRAADIAE ALYSVPRNPS QIPALSSSPA 
HSGMMGINSY GSQLGVSISE STQGNNQGYI RNTSSISPRG YSSSSTPQQS NYSTSSNSMN 
GYSNVPMANL GVPGSPGFLN GSPTGSPYGI MSSSPTVGSS STSSILPFSS SVFPAVKQKS 
AFAPVIRPQG SPSPACSSGN GNGFRAMTGL VVPPM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.