ADORA2B | ENSG00000170425 | NCBI 136

Details for: ADORA2B

Gene ID: 136

Symbol: ADORA2B

Ensembl ID: ENSG00000170425

Description: adenosine A2b receptor

Associated with

Adenosine p1 receptors
(R-HSA-417973)
Adora2b mediated anti-inflammatory cytokines production
(R-HSA-9660821)
Anti-inflammatory response favouring leishmania parasite infection
(R-HSA-9662851)
Class a/1 (rhodopsin-like receptors)
(R-HSA-373076)
Disease
(R-HSA-1643685)
G alpha (s) signalling events
(R-HSA-418555)
Gpcr downstream signalling
(R-HSA-388396)
Gpcr ligand binding
(R-HSA-500792)
Infectious disease
(R-HSA-5663205)
Leishmania infection
(R-HSA-9658195)
Leishmania parasite growth and survival
(R-HSA-9664433)
Metabolism of proteins
(R-HSA-392499)
Nucleotide-like (purinergic) receptors
(R-HSA-418038)
Parasitic infection pathways
(R-HSA-9824443)
Signaling by gpcr
(R-HSA-372790)
Signal transduction
(R-HSA-162582)
Surfactant metabolism
(R-HSA-5683826)
Activation of adenylate cyclase activity
(GO:0007190)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Cellular response to extracellular stimulus
(GO:0031668)
Cgmp-mediated signaling
(GO:0019934)
Glutamatergic synapse
(GO:0098978)
G protein-coupled adenosine receptor activity
(GO:0001609)
G protein-coupled adenosine receptor signaling pathway
(GO:0001973)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Mast cell degranulation
(GO:0043303)
Plasma membrane
(GO:0005886)
Positive regulation of cgmp-mediated signaling
(GO:0010753)
Positive regulation of chemokine production
(GO:0032722)
Positive regulation of chronic inflammatory response to non-antigenic stimulus
(GO:0002882)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of mast cell degranulation
(GO:0043306)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Presynapse
(GO:0098793)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Relaxation of vascular associated smooth muscle
(GO:0060087)
Schaffer collateral - ca1 synapse
(GO:0098685)
Vasodilation
(GO:0042311)

Other Information

Proteins

Adenosine receptor A2b

Genular Protein ID: 4217169827

Symbol: AA2BR_HUMAN

Name: Adenosine receptor A2b

UniProtKB Accession Codes:

P29275

Database IDs:

Citations:

PubMed ID: 1325798

Title: Molecular cloning and expression of an adenosine A2b receptor from human brain.

PubMed ID: 1325798

DOI: 10.1016/s0006-291x(05)81462-7

PubMed ID: 7558011

Title: Cloning and chromosomal localization of the human A2b adenosine receptor gene (ADORA2B) and its pseudogene.

PubMed ID: 7558011

DOI: 10.1006/geno.1995.1061

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 332
Mass: 36333
Checksum: 38AD088E2439C7FA
Sequence:

MLLETQDALY VALELVIAAL SVAGNVLVCA AVGTANTLQT PTNYFLVSLA AADVAVGLFA 
IPFAITISLG FCTDFYGCLF LACFVLVLTQ SSIFSLLAVA VDRYLAICVP LRYKSLVTGT 
RARGVIAVLW VLAFGIGLTP FLGWNSKDSA TNNCTEPWDG TTNESCCLVK CLFENVVPMS 
YMVYFNFFGC VLPPLLIMLV IYIKIFLVAC RQLQRTELMD HSRTTLQREI HAAKSLAMIV 
GIFALCWLPV HAVNCVTLFQ PAQGKNKPKW AMNMAILLSH ANSVVNPIVY AYRNRDFRYT 
FHKIISRYLL CQADVKSGNG QAGVQPALGV GL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.