Genular: Defining Cellular Identity and Function

Details for: Edar

Gene ID: 13608

Symbol: Edar

Ensembl ID: ENSMUSG00000003227

Description: ectodysplasin-A receptor

Associated with

Cytokine signaling in immune system
(R-MMU-1280215)
Immune system
(R-MMU-168256)
Tnfr2 non-canonical nf-kb pathway
(R-MMU-5668541)
Tnfs bind their physiological receptors
(R-MMU-5669034)
Apical part of cell
(GO:0045177)
Apoptotic process
(GO:0006915)
Cell differentiation
(GO:0030154)
Cytokine-mediated signaling pathway
(GO:0019221)
Hair follicle development
(GO:0001942)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Odontogenesis of dentin-containing tooth
(GO:0042475)
Pigmentation
(GO:0043473)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of jnk cascade
(GO:0046330)
Positive regulation of non-canonical nf-kappab signal transduction
(GO:1901224)
Salivary gland cavitation
(GO:0060662)
Signaling receptor activity
(GO:0038023)
Transmembrane signaling receptor activity
(GO:0004888)

Other Information

Proteins

Tumor necrosis factor receptor superfamily member EDAR

Genular Protein ID: 2138286095

Symbol: EDAR_MOUSE

Name: Tumor necrosis factor receptor superfamily member EDAR

UniProtKB Accession Codes:

Q9R187 Q9DC43

Database IDs:

Citations:

PubMed ID: 10431242

Title: Involvement of a novel Tnf receptor homologue in hair follicle induction.

PubMed ID: 10431242

DOI: 10.1038/11943

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 11203701

Title: TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis.

PubMed ID: 11203701

DOI: 10.1006/dbio.2000.9955

Sequence Information:

Length: 448
Mass: 48434
Checksum: FCCAF38F3D6BB971
Sequence:

MAHVGDCKWM SWLPVLVVSL MCSAKAEDSN CGENEYHNQT TGLCQQCPPC RPGEEPYMSC 
GYGTKDDDYG CVPCPAEKFS KGGYQICRRH KDCEGFFRAT VLTPGDMEND AECGPCLPGY 
YMLENRPRNI YGMVCYSCLL APPNTKECVG ATSGVSAHSS STSGGSTLSP FQHAHKELSG 
QGHLATALII AMSTIFIMAI AIVLIIMFYI MKTKPSAPAC CSSPPGKSAE APANTHEEKK 
EAPDSVVTFP ENGEFQKLTA TPTKTPKSEN DASSENEQLL SRSVDSDEEP APDKQGSPEL 
CLLSLVHLAR EKSVTSNKSA GIQSRRKKIL DVYANVCGVV EGLSPTELPF DCLEKTSRML 
SSTYNSEKAV VKTWRHLAES FGLKRDEIGG MTDGMQLFDR ISTAGYSIPE LLTKLVQIER 
LDAVESLCAD ILEWAGVVPP ASPPPAAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.