Details for: S1pr1

Gene ID: 13609

Symbol: S1pr1

Ensembl ID: ENSMUSG00000045092

Description: sphingosine-1-phosphate receptor 1

Associated with

Other Information

Genular Protein ID: 3056794016

Symbol: S1PR1_MOUSE

Name: Endothelial differentiation G-protein coupled receptor 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9226368

Title: The mouse gene for the inducible G-protein-coupled receptor edg-1.

PubMed ID: 9226368

DOI: 10.1006/geno.1997.4759

PubMed ID: 9931453

Title: Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate.

PubMed ID: 9931453

DOI: 10.1016/s0378-1119(98)00589-7

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11032855

Title: Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation.

PubMed ID: 11032855

DOI: 10.1172/jci10905

PubMed ID: 11726541

Title: EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration.

PubMed ID: 11726541

DOI: 10.1096/fj.01-0523com

PubMed ID: 11230698

Title: Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility.

PubMed ID: 11230698

DOI: 10.1126/science.1057559

PubMed ID: 12869509

Title: G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

PubMed ID: 12869509

DOI: 10.1182/blood-2003-02-0460

PubMed ID: 14732704

Title: Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration.

PubMed ID: 14732704

DOI: 10.1074/jbc.m314291200

PubMed ID: 16314531

Title: Essential role for sphingosine kinases in neural and vascular development.

PubMed ID: 16314531

DOI: 10.1128/mcb.25.24.11113-11121.2005

PubMed ID: 14737169

Title: Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1.

PubMed ID: 14737169

DOI: 10.1038/nature02284

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19286607

Title: Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.

PubMed ID: 19286607

DOI: 10.1161/circresaha.108.193367

PubMed ID: 19204730

Title: Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis.

PubMed ID: 19204730

DOI: 10.1038/nature07713

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21668976

Title: The Sphingosine-1-phosphate receptor 1 mediates S1P action during cardiac development.

PubMed ID: 21668976

DOI: 10.1186/1471-213x-11-37

PubMed ID: 22951644

Title: S1P1 inhibits sprouting angiogenesis during vascular development.

PubMed ID: 22951644

DOI: 10.1242/dev.078550

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

  • Length: 382
  • Mass: 42639
  • Checksum: 5FE4C9A2BD65CB2A
  • Sequence:
  • MVSTSIPEVK ALRSSVSDYG NYDIIVRHYN YTGKLNIGAE KDHGIKLTSV VFILICCFII 
    LENIFVLLTI WKTKKFHRPM YYFIGNLALS DLLAGVAYTA NLLLSGATTY KLTPAQWFLR 
    EGSMFVALSA SVFSLLAIAI ERYITMLKMK LHNGSNSSRS FLLISACWVI SLILGGLPIM 
    GWNCISSLSS CSTVLPLYHK HYILFCTTVF TLLLLSIVIL YCRIYSLVRT RSRRLTFRKN 
    ISKASRSSEK SLALLKTVII VLSVFIACWA PLFILLLLDV GCKAKTCDIL YKAEYFLVLA 
    VLNSGTNPII YTLTNKEMRR AFIRIVSCCK CPNGDSAGKF KRPIIPGMEF SRSKSDNSSH 
    PQKDDGDNPE TIMSSGNVNS SS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.