Genular: Defining Cellular Identity and Function

Details for: Edn3

Gene ID: 13616

Symbol: Edn3

Ensembl ID: ENSMUSG00000027524

Description: endothelin 3

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Axon extension
(GO:0048675)
Axon guidance
(GO:0007411)
Blood vessel diameter maintenance
(GO:0097746)
Cell population proliferation
(GO:0008283)
Cell surface receptor signaling pathway
(GO:0007166)
Endothelin b receptor binding
(GO:0031708)
Establishment of localization in cell
(GO:0051649)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hormone activity
(GO:0005179)
Intracellular calcium ion homeostasis
(GO:0006874)
Intracellular magnesium ion homeostasis
(GO:0010961)
Melanocyte differentiation
(GO:0030318)
Negative regulation of hormone secretion
(GO:0046888)
Neural crest cell migration
(GO:0001755)
Neuron differentiation
(GO:0030182)
Neuron projection development
(GO:0031175)
Neutrophil chemotaxis
(GO:0030593)
Peptide hormone secretion
(GO:0030072)
Positive regulation of cell differentiation
(GO:0045597)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of heart rate
(GO:0010460)
Positive regulation of hormone secretion
(GO:0046887)
Positive regulation of leukocyte chemotaxis
(GO:0002690)
Positive regulation of map kinase activity
(GO:0043406)
Positive regulation of mitotic nuclear division
(GO:0045840)
Positive regulation of potassium ion transmembrane transport
(GO:1901381)
Positive regulation of prostaglandin-endoperoxide synthase activity
(GO:0060585)
Potassium ion transmembrane transport
(GO:0071805)
Regulation of cell migration
(GO:0030334)
Regulation of developmental pigmentation
(GO:0048070)
Regulation of gene expression
(GO:0010468)
Regulation of neurotransmitter secretion
(GO:0046928)
Regulation of systemic arterial blood pressure by endothelin
(GO:0003100)
Regulation of vasoconstriction
(GO:0019229)
Vasoconstriction
(GO:0042310)
Vein smooth muscle contraction
(GO:0014826)

Other Information

Proteins

Endothelin-3

Genular Protein ID: 2409237275

Symbol: EDN3_MOUSE

Name: Endothelin-3

UniProtKB Accession Codes:

P48299 Q543L0

Database IDs:

Citations:

PubMed ID: 8001160

Title: Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons.

PubMed ID: 8001160

DOI: 10.1016/0092-8674(94)90018-3

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

Length: 214
Mass: 23322
Checksum: 8911260872D6A713
Sequence:

MEPGLWLLLG LTVTSAAGLV PCPQSGDSGR ASVSQGPPEA GSERGCEETV AGPGERIVSP 
TVALPAQPES AGQERAPGRS GKQEDKGLPA HHRPRRCTCF TYKDKECVYY CHLDIIWINT 
PEQTVPYGLS NYRESLRGKR SLGPVPESSQ PSPWTRLRCT CMGADDKACA HFCARTRDVT 
SYSGRAERPA AEEMRETGGP RQRLMSRTDK AHRP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.