Genular: Defining Cellular Identity and Function

Details for: Ednrb

Gene ID: 13618

Symbol: Ednrb

Ensembl ID: ENSMUSG00000022122

Description: endothelin receptor type B

Associated with

Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (q) signalling events
(R-MMU-416476)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Peptide ligand-binding receptors
(R-MMU-375276)
Signaling by gpcr
(R-MMU-372790)
Aldosterone metabolic process
(GO:0032341)
Calcium-mediated signaling
(GO:0019722)
Calcium ion transmembrane transport
(GO:0070588)
Canonical wnt signaling pathway
(GO:0060070)
Cgmp-mediated signaling
(GO:0019934)
Chordate pharynx development
(GO:0160093)
Developmental pigmentation
(GO:0048066)
Endothelin receptor activity
(GO:0004962)
Endothelin receptor signaling pathway
(GO:0086100)
Enteric nervous system development
(GO:0048484)
Enteric smooth muscle cell differentiation
(GO:0035645)
Epithelial fluid transport
(GO:0042045)
Establishment of endothelial barrier
(GO:0061028)
Gene expression
(GO:0010467)
G protein-coupled receptor activity
(GO:0004930)
G protein-coupled receptor signaling pathway
(GO:0007186)
Heparin metabolic process
(GO:0030202)
Macrophage chemotaxis
(GO:0048246)
Melanocyte differentiation
(GO:0030318)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of neuron maturation
(GO:0014043)
Negative regulation of protein metabolic process
(GO:0051248)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neural crest cell migration
(GO:0001755)
Neuroblast migration
(GO:0097402)
Nuclear membrane
(GO:0031965)
Peptide hormone binding
(GO:0017046)
Peripheral nervous system development
(GO:0007422)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Pigmentation
(GO:0043473)
Plasma membrane
(GO:0005886)
Podocyte differentiation
(GO:0072112)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of penile erection
(GO:0060406)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of urine volume
(GO:0035810)
Posterior midgut development
(GO:0007497)
Protein binding
(GO:0005515)
Protein transmembrane transport
(GO:0071806)
Regulation of blood pressure
(GO:0008217)
Regulation of epithelial cell proliferation
(GO:0050678)
Regulation of fever generation
(GO:0031620)
Regulation of heart rate
(GO:0002027)
Regulation of ph
(GO:0006885)
Renal albumin absorption
(GO:0097018)
Renal sodium excretion
(GO:0035812)
Renal sodium ion absorption
(GO:0070294)
Renin secretion into blood stream
(GO:0002001)
Response to endothelin
(GO:1990839)
Response to lipopolysaccharide
(GO:0032496)
Response to organic substance
(GO:0010033)
Response to pain
(GO:0048265)
Response to sodium phosphate
(GO:1904383)
Signal transduction
(GO:0007165)
Sodium ion homeostasis
(GO:0055078)
Type 1 angiotensin receptor binding
(GO:0031702)
Vasoconstriction
(GO:0042310)
Vasodilation
(GO:0042311)
Vein smooth muscle contraction
(GO:0014826)

Other Information

Proteins

Endothelin receptor non-selective type

Genular Protein ID: 3606269129

Symbol: EDNRB_MOUSE

Name: Endothelin receptor non-selective type

UniProtKB Accession Codes:

P48302 Q542M3

Database IDs:

Citations:

PubMed ID: 8001159

Title: Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice.

PubMed ID: 8001159

DOI: 10.1016/0092-8674(94)90017-5

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 442
Mass: 49561
Checksum: ED28A676F854B3D1
Sequence:

MQSPASRCGR ALVALLLACG FLGVWGEKRG FPPAQATLSL LGTKEVMTPP TKTSWTRGSN 
SSLMRSSAPA EVTKGGRGAG VPPRSFPPPC QRNIEISKTF KYINTIVSCL VFVLGIIGNS 
TLLRIIYKNK CMRNGPNILI ASLALGDLLH IIIDIPINTY KLLAEDWPFG AEMCKLVPFI 
QKASVGITVL SLCALSIDRY RAVASWSRIK GIGVPKWTAV EIVLIWVVSV VLAVPEAIGF 
DMITSDYKGK PLRVCMLNPF QKTAFMQFYK TAKDWWLFSF YFCLPLAITA VFYTLMTCEM 
LRKKSGMQIA LNDHLKQRRE VAKTVFCLVL VFALCWLPLH LSRILKLTLY DQSNPHRCEL 
LSFLLVLDYI GINMASLNSC INPIALYLVS KRFKNCFKSC LCCWCQTFEE KQSLEEKQSC 
LKFKANDHGY DNFRSSNKYS SS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.