Details for: CPD
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 20.78rCSI 29.95%PRS 43.79
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CSI 20.52rCSI 21.99%PRS 27.91
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CSI 15.67rCSI 48.98%PRS 19.61
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CSI 14.58rCSI 25.21%PRS 23.21
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CSI 14.47rCSI 22.1%PRS 37.95
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CSI 12.32rCSI 19.56%PRS 38.38
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CSI 10.84rCSI 18.2%PRS 18.72
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CSI 10.5rCSI 62.91%PRS 46.73
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CSI 10.18rCSI 24.21%PRS 42.23
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CSI 8.8rCSI 19.44%PRS 21.73
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CSI 8.41rCSI 47.08%PRS 45.53
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CSI 8.4rCSI 27.04%PRS 30.77
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CSI 8.23rCSI 12.05%PRS 32.37
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CSI 8.21rCSI 29.53%PRS 17.8
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CSI 8.06rCSI 19.58%PRS 18.24
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CSI 6.95rCSI 39.55%PRS 67.19
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CSI 6.8rCSI 16.83%PRS 28.23
-
CSI 6.68rCSI 8.07%PRS 35.83
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CSI 6.46rCSI 24.19%PRS 25.43
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CSI 6.36rCSI 13.89%PRS 51.29
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CSI 6.15rCSI 9.81%PRS 25.64
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CSI 6.1rCSI 13.62%PRS 35.03
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CSI 5.9rCSI 4.43%PRS 32.16
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CSI 5.87rCSI 23.46%PRS 53.64
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CSI 5.72rCSI 15.77%PRS 28.07
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CSI 5.69rCSI 8.4%PRS 45.05
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CSI 5.65rCSI 8.07%PRS 32.75
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CSI 5.6rCSI 6.13%PRS 33.27
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CSI 5.53rCSI 9.45%PRS 51.36
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CSI 5.38rCSI 4.07%PRS 40.41
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CSI 5.09rCSI 6.19%PRS 36.63
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CSI 4.95rCSI 11.81%PRS 33.05
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CSI 4.93rCSI 3.99%PRS 30.2
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CSI 4.78rCSI 7.35%PRS 36.38
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CSI 4.34rCSI 6.63%PRS 47.88
-
CSI 4.28rCSI 6.54%PRS 30.33
-
CSI 4.24rCSI 6%PRS 27.92
-
CSI 3.97rCSI 3.49%PRS 22.17
-
CSI 3.97rCSI 6.39%PRS 41.34
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CSI 3.91rCSI 3.18%PRS 31.01
-
CSI 3.84rCSI 8.61%PRS 19.33
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CSI 3.84rCSI 9.16%PRS 41.72
-
CSI 3.73rCSI 6.59%PRS 18.17
-
CSI 3.61rCSI 2.99%PRS 28.64
-
CSI 3.45rCSI 2.63%PRS 39.12
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CSI 3.45rCSI 9.23%PRS 25.3
-
CSI 3.39rCSI 79.05%PRS 51.89
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CSI 3.35rCSI 5.29%PRS 30.53
-
CSI 3.34rCSI 18.25%PRS 38.44
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CSI 3.33rCSI 3.86%PRS 40.87
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CSI 3.27rCSI 4.19%PRS 34.44
-
CSI 3.13rCSI 2.43%PRS 29.49
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CSI 2.98rCSI 1.76%PRS 41.61
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CSI 2.97rCSI 12.82%PRS 48.16
-
CSI 2.85rCSI 7.36%PRS 27.71
-
CSI 2.76rCSI 4.03%PRS 31.97
-
CSI 2.74rCSI 6.56%PRS 47.77
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CSI 2.72rCSI 4.01%PRS 27.89
-
CSI 2.72rCSI 1.89%PRS 41.08
-
CSI 2.63rCSI 2.74%PRS 30.71
-
CSI 2.59rCSI 3.04%PRS 33.75
-
CSI 2.49rCSI 1.84%PRS 25.86
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CSI 2.49rCSI 4.66%PRS 22.47
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CSI 2.49rCSI 2.87%PRS 26.11
-
CSI 2.48rCSI 2.44%PRS 32.12
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CSI 2.48rCSI 7.17%PRS 23.94
-
CSI 2.47rCSI 7.33%PRS 40.01
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CSI 2.45rCSI 58.73%PRS 17.91
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CSI 2.44rCSI 6.18%PRS 36.64
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CSI 2.42rCSI 2.33%PRS 22.74
-
CSI 2.42rCSI 6.3%PRS 30.21
-
CSI 2.41rCSI 5.31%PRS 43.52
-
CSI 2.41rCSI 20.75%PRS 19.22
-
CSI 2.33rCSI 5.48%PRS 40.19
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CSI 2.3rCSI 55.48%PRS 18.69
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CSI 2.26rCSI 4.53%PRS 22.57
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CSI 2.21rCSI 1.91%PRS 33.38
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CSI 2.17rCSI 4.13%PRS 45.41
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CSI 2.11rCSI 2.89%PRS 33.75
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CSI 2.11rCSI 1.99%PRS 31.21
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CSI 2.07rCSI 5.41%PRS 41
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CSI 2.07rCSI 1.84%PRS 29.95
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CSI 2.07rCSI 4.41%PRS 44.52
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CSI 2.03rCSI 1.58%PRS 43.49
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CSI 2.02rCSI 4.2%PRS 29.38
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CSI 2.02rCSI 7.86%PRS 39.49
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CSI 2rCSI 4.62%PRS 24.66
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CSI 1.99rCSI 1.81%PRS 43.67
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CSI 1.97rCSI 4.42%PRS 51.71
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CSI 1.96rCSI 3.17%PRS 29.74
-
CSI 1.96rCSI 2.67%PRS 32.81
-
CSI 1.94rCSI 7.91%PRS 30.15
-
CSI 1.92rCSI 2.85%PRS 33.53
-
CSI 1.91rCSI 2.38%PRS 17.61
-
CSI 1.89rCSI 3.77%PRS 47.21
-
CSI 1.87rCSI 2.51%PRS 37.17
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CSI 1.86rCSI 4.25%PRS 25.83
-
CSI 1.85rCSI 4.22%PRS 29.56
-
CSI 1.83rCSI 1.9%PRS 35.01
-
CSI 1.8rCSI 3.09%PRS 38.95
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CSI 0.2rCSI 0.9%PRS 42.1%
-
CSI 0.2rCSI 0.3%PRS 39.9%
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CSI 0.3rCSI 1.4%PRS 38.9%
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CSI 0.4rCSI 2.0%PRS 56.6%
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CSI 0.4rCSI 1.3%PRS 25.5%
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CSI 0.4rCSI 1.6%PRS 46.3%
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CSI 0.4rCSI 3.0%PRS 20.4%
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CSI 0.4rCSI 6.5%PRS 59.8%
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CSI 0.4rCSI 1.5%PRS 42.3%
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CSI 0.4rCSI 1.7%PRS 19.5%
-
CSI 0.5rCSI 2.0%PRS 29.0%
-
CSI 0.5rCSI 2.8%PRS 24.4%
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CSI 0.5rCSI 3.2%PRS 61.0%
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CSI 0.5rCSI 2.5%PRS 39.6%
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CSI 0.5rCSI 1.2%PRS 22.0%
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CSI 0.6rCSI 2.1%PRS 27.3%
-
CSI 0.6rCSI 2.6%PRS 55.7%
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CSI 0.6rCSI 1.4%PRS 23.3%
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CSI 0.6rCSI 3.5%PRS 56.6%
-
CSI 0.6rCSI 1.9%PRS 21.8%
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CSI 0.6rCSI 1.7%PRS 47.9%
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CSI 0.6rCSI 6.8%PRS 69.6%
-
CSI 0.6rCSI 1.2%PRS 31.1%
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CSI 0.6rCSI 1.4%PRS 39.0%
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CSI 0.7rCSI 1.4%PRS 27.8%
-
CSI 0.7rCSI 1.8%PRS 38.2%
-
CSI 0.7rCSI 1.1%PRS 23.3%
-
CSI 0.7rCSI 4.0%PRS 30.4%
-
CSI 0.7rCSI 0.5%PRS 28.5%
-
CSI 0.7rCSI 3.2%PRS 28.2%
-
CSI 0.7rCSI 1.5%PRS 28.1%
-
CSI 0.8rCSI 0.8%PRS 30.9%
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CSI 0.8rCSI 1.2%PRS 23.8%
-
CSI 0.8rCSI 1.2%PRS 27.7%
-
CSI 0.8rCSI 2.3%PRS 44.3%
-
CSI 0.9rCSI 6.9%PRS 27.8%
-
CSI 0.9rCSI 1.0%PRS 22.6%
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CSI 0.9rCSI 1.2%PRS 42.3%
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CSI 0.9rCSI 1.4%PRS 34.0%
-
CSI 0.9rCSI 1.7%PRS 51.6%
-
CSI 0.9rCSI 1.8%PRS 30.6%
-
CSI 0.9rCSI 1.4%PRS 30.9%
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CSI 1.0rCSI 3.9%PRS 28.7%
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CSI 1.0rCSI 2.1%PRS 23.1%
-
CSI 1.0rCSI 3.4%PRS 44.6%
-
CSI 1.0rCSI 5.2%PRS 31.9%
-
CSI 1.0rCSI 2.6%PRS 28.9%
-
CSI 1.0rCSI 7.2%PRS 29.2%
-
CSI 1.0rCSI 2.1%PRS 40.0%
-
CSI 1.0rCSI 2.4%PRS 30.1%
-
CSI 1.1rCSI 1.3%PRS 48.7%
-
CSI 1.1rCSI 1.5%PRS 28.9%
-
CSI 1.1rCSI 3.7%PRS 22.2%
-
CSI 1.1rCSI 1.4%PRS 19.4%
-
CSI 1.2rCSI 1.9%PRS 34.8%
-
CSI 1.2rCSI 10.2%PRS 36.8%
-
CSI 1.2rCSI 1.4%PRS 18.6%
-
CSI 1.2rCSI 3.1%PRS 36.1%
-
CSI 1.2rCSI 1.3%PRS 46.2%
-
CSI 1.2rCSI 1.6%PRS 41.7%
-
CSI 1.2rCSI 1.2%PRS 48.8%
-
CSI 1.2rCSI 3.5%PRS 44.1%
-
CSI 1.2rCSI 8.3%PRS 51.0%
-
CSI 1.2rCSI 6.5%PRS 46.8%
-
CSI 1.2rCSI 3.8%PRS 41.9%
-
CSI 1.2rCSI 1.7%PRS 32.1%
-
CSI 1.2rCSI 3.9%PRS 21.3%
-
CSI 1.3rCSI 4.9%PRS 50.7%
-
CSI 1.3rCSI 1.8%PRS 38.2%
-
CSI 1.3rCSI 2.3%PRS 28.3%
-
CSI 1.3rCSI 1.9%PRS 38.9%
-
CSI 1.3rCSI 2.3%PRS 25.2%
-
CSI 1.3rCSI 2.1%PRS 28.3%
-
CSI 1.4rCSI 2.2%PRS 32.8%
-
CSI 1.4rCSI 3.3%PRS 35.8%
-
CSI 1.4rCSI 1.6%PRS 45.1%
-
CSI 1.4rCSI 1.5%PRS 31.8%
-
CSI 1.4rCSI 1.9%PRS 41.5%
-
CSI 1.4rCSI 2.5%PRS 29.3%
-
CSI 1.5rCSI 2.6%PRS 44.3%
-
CSI 1.5rCSI 2.3%PRS 20.4%
-
CSI 1.5rCSI 1.5%PRS 28.0%
-
CSI 1.5rCSI 7.0%PRS 34.1%
-
CSI 1.5rCSI 1.2%PRS 50.0%
-
CSI 1.5rCSI 1.8%PRS 40.2%
-
CSI 1.5rCSI 3.3%PRS 33.7%
-
CSI 1.5rCSI 7.6%PRS 72.8%
-
CSI 1.5rCSI 2.7%PRS 45.6%
-
CSI 1.5rCSI 2.9%PRS 66.0%
-
CSI 1.5rCSI 1.4%PRS 35.7%
-
CSI 1.6rCSI 2.3%PRS 34.0%
-
CSI 1.6rCSI 1.8%PRS 41.9%
-
CSI 1.6rCSI 1.6%PRS 25.7%
-
CSI 1.6rCSI 8.9%PRS 19.7%
-
CSI 1.6rCSI 2.5%PRS 25.4%
-
CSI 1.6rCSI 5.6%PRS 46.7%
-
CSI 1.6rCSI 9.5%PRS 19.7%
-
CSI 1.6rCSI 1.7%PRS 30.7%
-
CSI 1.6rCSI 3.3%PRS 17.2%
-
CSI 1.6rCSI 2.7%PRS 23.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2472666290
Symbol: CBPD_HUMAN
Name: Carboxypeptidase D
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9714835
Title: Cloning, functional expression, and chromosomal localization of the human and mouse gp180-carboxypeptidase D-like enzyme.
PubMed ID: 9714835
PubMed ID: 9355738
Title: Sequence of human carboxypeptidase D reveals it to be a member of the regulatory carboxypeptidase family with three tandem active site domains.
PubMed ID: 9355738
DOI: 10.1042/bj3270081
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9064476
Title: Identification of a membrane-bound carboxypeptidase as the mammalian homolog of duck gp180, a hepatitis B virus-binding protein.
PubMed ID: 9064476
PubMed ID: 12643288
Title: Palmitoylation of carboxypeptidase D. Implications for intracellular trafficking.
PubMed ID: 12643288
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 1380
- Mass: 152931
- Checksum: 567EC1F0B4B7A0C8
- Sequence:
MASGRDERPP WRLGRLLLLM CLLLLGSSAR AAHIKKAEAT TTTTSAGAEA AEGQFDRYYH EEELESALRE AAAAGLPGLA RLFSIGRSVE GRPLWVLRLT AGLGSLIPEG DAGPDAAGPD AAGPLLPGRP QVKLVGNMHG DETVSRQVLI YLARELAAGY RRGDPRLVRL LNTTDVYLLP SLNPDGFERA REGDCGFGDG GPSGASGRDN SRGRDLNRSF PDQFSTGEPP ALDEVPEVRA LIEWIRRNKF VLSGNLHGGS VVASYPFDDS PEHKATGIYS KTSDDEVFKY LAKAYASNHP IMKTGEPHCP GDEDETFKDG ITNGAHWYDV EGGMQDYNYV WANCFEITLE LSCCKYPPAS QLRQEWENNR ESLITLIEKV HIGVKGFVKD SITGSGLENA TISVAGINHN ITTGRFGDFY RLLVPGTYNL TVVLTGYMPL TVTNVVVKEG PATEVDFSLR PTVTSVIPDT TEAVSTASTV AIPNILSGTS SSYQPIQPKD FHHHHFPDME IFLRRFANEY PNITRLYSLG KSVESRELYV MEISDNPGVH EPGEPEFKYI GNMHGNEVVG RELLLNLIEY LCKNFGTDPE VTDLVHNTRI HLMPSMNPDG YEKSQEGDSI SVIGRNNSNN FDLNRNFPDQ FVQITDPTQP ETIAVMSWMK SYPFVLSANL HGGSLVVNYP FDDDEQGLAT YSKSPDDAVF QQIALSYSKE NSQMFQGRPC KNMYPNEYFP HGITNGASWY NVPGGMQDWN YLQTNCFEVT IELGCVKYPL EKELPNFWEQ NRRSLIQFMK QVHQGVRGFV LDATDGRGIL NATISVAEIN HPVTTYKTGD YWRLLVPGTY KITASARGYN PVTKNVTVKS EGAIQVNFTL VRSSTDSNNE SKKGKGASSS TNDASDPTTK EFETLIKDLS AENGLESLML RSSSNLALAL YRYHSYKDLS EFLRGLVMNY PHITNLTNLG QSTEYRHIWS LEISNKPNVS EPEEPKIRFV AGIHGNAPVG TELLLALAEF LCLNYKKNPA VTQLVDRTRI VIVPSLNPDG RERAQEKDCT SKIGQTNARG KDLDTDFTNN ASQPETKAII ENLIQKQDFS LSVALDGGSM LVTYPYDKPV QTVENKETLK HLASLYANNH PSMHMGQPSC PNKSDENIPG GVMRGAEWHS HLGSMKDYSV TYGHCPEITV YTSCCYFPSA ARLPSLWADN KRSLLSMLVE VHKGVHGFVK DKTGKPISKA VIVLNEGIKV QTKEGGYFHV LLAPGVHNII AIADGYQQQH SQVFVHHDAA SSVVIVFDTD NRIFGLPREL VVTVSGATMS ALILTACIIW CICSIKSNRH KDGFHRLRQH HDEYEDEIRM MSTGSKKSLL SHEFQDETDT EEETLYSSKH