Genular: Defining Cellular Identity and Function

Details for: Eef2

Gene ID: 13629

Symbol: Eef2

Ensembl ID: ENSMUSG00000034994

Description: eukaryotic translation elongation factor 2

Associated with

Eukaryotic translation elongation
(R-MMU-156842)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-MMU-163841)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Peptide chain elongation
(R-MMU-156902)
Post-translational protein modification
(R-MMU-597592)
Protein methylation
(R-MMU-8876725)
Synthesis of diphthamide-eef2
(R-MMU-5358493)
5s rrna binding
(GO:0008097)
Actin filament binding
(GO:0051015)
Aggresome
(GO:0016235)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Glutamatergic synapse
(GO:0098978)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Hydrolase activity
(GO:0016787)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
P53 binding
(GO:0002039)
Plasma membrane
(GO:0005886)
Positive regulation of cytoplasmic translation
(GO:2000767)
Positive regulation of translation
(GO:0045727)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Ribonucleoprotein complex
(GO:1990904)
Ribosome
(GO:0005840)
Ribosome binding
(GO:0043022)
Rna binding
(GO:0003723)
Synapse
(GO:0045202)
Translation
(GO:0006412)
Translational elongation
(GO:0006414)
Translation at postsynapse
(GO:0140242)
Translation elongation factor activity
(GO:0003746)

Other Information

Proteins

Elongation factor 2

Genular Protein ID: 139217262

Symbol: EF2_MOUSE

Name: Elongation factor 2

UniProtKB Accession Codes:

P58252 Q544E4

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16139798

Title: Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.

PubMed ID: 16139798

DOI: 10.1016/j.bbrc.2005.08.132

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 34815424

Title: Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.

PubMed ID: 34815424

DOI: 10.1038/s41467-021-27160-4

Sequence Information:

Length: 858
Mass: 95314
Checksum: 0569DFFB9B1DB5F6
Sequence:

MVNFTVDQIR AIMDKKANIR NMSVIAHVDH GKSTLTDSLV CKAGIIASAR AGETRFTDTR 
KDEQERCITI KSTAISLFYE LSENDLNFIK QSKDGSGFLI NLIDSPGHVD FSSEVTAALR 
VTDGALVVVD CVSGVCVQTE TVLRQAIAER IKPVLMMNKM DRALLELQLE PEELYQTFQR 
IVENVNVIIS TYGEGESGPM GNIMIDPVLG TVGFGSGLHG WAFTLKQFAE MYVAKFAAKG 
EGQLSAAERA KKVEDMMKKL WGDRYFDPAN GKFSKSANSP DGKKLPRTFC QLILDPIFKV 
FDAIMNFRKE ETAKLIEKLD IKLDSEDKDK EGKPLLKAVM RRWLPAGDAL LQMITIHLPS 
PVTAQKYRCE LLYEGPPDDE AAMGIKSCDP KGPLMMYISK MVPTSDKGRF YAFGRVFSGV 
VSTGLKVRIM GPNYTPGKKE DLYLKPIQRT ILMMGRYVEP IEDVPCGNIV GLVGVDQFLV 
KTGTITTFEH AHNMRVMKFS VSPVVRVAVE AKNPADLPKL VEGLKRLAKS DPMVQCIIEE 
SGEHIIAGAG ELHLEICLKD LEEDHACIPI KKSDPVVSYR ETVSEESNVL CLSKSPNKHN 
RLYMKARPFP DGLAEDIDKG EVSARQELKA RARYLAEKYE WDVAEARKIW CFGPDGTGPN 
ILTDITKGVQ YLNEIKDSVV AGFQWATKEG ALCEENMRGV RFDVHDVTLH ADAIHRGGGQ 
IIPTARRCLY ASVLTAQPRL MEPIYLVEIQ CPEQVVGGIY GVLNRKRGHV FEESQVAGTP 
MFVVKAYLPV NESFGFTADL RSNTGGQAFP QCVFDHWQIL PGDPFDNSSR PSQVVAETRK 
RKGLKEGIPA LDNFLDKL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Eef2

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. PubMed ID: 16139798

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337