Genular: Defining Cellular Identity and Function

Details for: Efna5

Gene ID: 13640

Symbol: Efna5

Ensembl ID: ENSMUSG00000048915

Description: ephrin A5

Associated with

Developmental biology
(R-MMU-1266738)
Eph-ephrin mediated repulsion of cells
(R-MMU-3928665)
Eph-ephrin signaling
(R-MMU-2682334)
Epha-mediated growth cone collapse
(R-MMU-3928663)
Adherens junction
(GO:0005912)
Axon guidance
(GO:0007411)
Basement membrane
(GO:0005604)
Cell differentiation
(GO:0030154)
Cell periphery
(GO:0071944)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Cellular response to forskolin
(GO:1904322)
Chemorepellent activity
(GO:0045499)
Collateral sprouting
(GO:0048668)
Ephrin receptor binding
(GO:0046875)
Ephrin receptor signaling pathway
(GO:0048013)
External side of plasma membrane
(GO:0009897)
Gaba-ergic synapse
(GO:0098982)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Negative regulation of substrate adhesion-dependent cell spreading
(GO:1900025)
Nervous system development
(GO:0007399)
Neurotrophin trkb receptor binding
(GO:0005169)
Plasma membrane
(GO:0005886)
Positive regulation of collateral sprouting
(GO:0048672)
Positive regulation of peptidyl-tyrosine phosphorylation
(GO:0050731)
Positive regulation of synapse assembly
(GO:0051965)
Protein binding
(GO:0005515)
Regulation of actin cytoskeleton organization
(GO:0032956)
Regulation of cell-cell adhesion
(GO:0022407)
Regulation of cell morphogenesis
(GO:0022604)
Regulation of focal adhesion assembly
(GO:0051893)
Regulation of gtpase activity
(GO:0043087)
Regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0061178)
Regulation of microtubule cytoskeleton organization
(GO:0070507)
Retinal ganglion cell axon guidance
(GO:0031290)
Side of membrane
(GO:0098552)
Synaptic membrane adhesion
(GO:0099560)

Other Information

Proteins

Ephrin-A5

Genular Protein ID: 1789631510

Symbol: EFNA5_MOUSE

Name: Ephrin-A5

UniProtKB Accession Codes:

O08543 O08544

Database IDs:

Citations:

PubMed ID: 8903354

Title: Distinct and overlapping expression patterns of ligands for Eph-related receptor tyrosine kinases during mouse embryogenesis.

PubMed ID: 8903354

DOI: 10.1006/dbio.1996.0269

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9053851

Title: The Eek receptor, a member of the Eph family of tyrosine protein kinases, can be activated by three different Eph family ligands.

PubMed ID: 9053851

DOI: 10.1038/sj.onc.1200857

PubMed ID: 11089974

Title: Regulation of repulsion versus adhesion by different splice forms of an Eph receptor.

PubMed ID: 11089974

DOI: 10.1038/35041577

PubMed ID: 17448994

Title: EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets.

PubMed ID: 17448994

DOI: 10.1016/j.cell.2007.02.044

PubMed ID: 18948590

Title: Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract.

PubMed ID: 18948590

DOI: 10.1073/pnas.0808987105

PubMed ID: 19656770

Title: The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.

PubMed ID: 19656770

DOI: 10.1074/mcp.m900195-mcp200

PubMed ID: 27446912

Title: Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis.

PubMed ID: 27446912

DOI: 10.3389/fcell.2016.00058

PubMed ID: 15107857

Title: Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

PubMed ID: 15107857

DOI: 10.1038/nn1237

Sequence Information:

Length: 228
Mass: 26339
Checksum: 85439F5337420022
Sequence:

MLHVEMLTLL FLVLWMCVFS QDPGSKVVAD RYAVYWNSSN PRFQRGDYHI DVCINDYLDV 
FCPHYEDSVP EDKTERYVLY MVNFDGYSAC DHTSKGFKRW ECNRPHSPNG PLKFSEKFQL 
FTPFSLGFEF RPGREYFYIS SAIPDNGRRS CLKLKVFVRP TNSCMKTIGV HDRVFDVNDK 
VENSLEPADD TVHESAEPSR GENAAQTPRI PSRLLAILLF LLAMLLTL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Efna5

Associated with

Other Information

Distinct and overlapping expression patterns of ligands for Eph-related receptor tyrosine kinases during mouse embryogenesis. PubMed ID: 8903354

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The Eek receptor, a member of the Eph family of tyrosine protein kinases, can be activated by three different Eph family ligands. PubMed ID: 9053851

Regulation of repulsion versus adhesion by different splice forms of an Eph receptor. PubMed ID: 11089974

EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. PubMed ID: 17448994

Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract. PubMed ID: 18948590

The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. PubMed ID: 19656770

Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis. PubMed ID: 27446912

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling. PubMed ID: 15107857