Details for: Egr2

Gene ID: 13654

Symbol: Egr2

Ensembl ID: ENSMUSG00000037868

Description: early growth response 2

Associated with

Other Information

Genular Protein ID: 1543026353

Symbol: EGR2_MOUSE

Name: E3 SUMO-protein ligase EGR2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2496302

Title: Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

PubMed ID: 2496302

DOI: 10.1128/mcb.9.2.787-797.1989

PubMed ID: 3129290

Title: A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

PubMed ID: 3129290

DOI: 10.1002/j.1460-2075.1988.tb02780.x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2452975

Title: Characterization of a mouse multigene family that encodes zinc finger structures.

PubMed ID: 2452975

DOI: 10.1128/mcb.8.3.1319-1326.1988

PubMed ID: 1969796

Title: The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.

PubMed ID: 1969796

DOI: 10.1002/j.1460-2075.1990.tb08228.x

PubMed ID: 1674431

Title: Krox-20: a candidate gene for the regulation of pattern formation in the hindbrain.

PubMed ID: 1674431

DOI: 10.1016/0300-9084(91)90079-g

PubMed ID: 1598206

Title: Mapping functional regions of the segment-specific transcription factor Krox-20.

PubMed ID: 1598206

DOI: 10.1093/nar/20.10.2485

PubMed ID: 8093858

Title: The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation.

PubMed ID: 8093858

DOI: 10.1016/0092-8674(93)90659-e

PubMed ID: 7935840

Title: Krox-20 controls myelination in the peripheral nervous system.

PubMed ID: 7935840

DOI: 10.1038/371796a0

PubMed ID: 10068633

Title: Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells.

PubMed ID: 10068633

DOI: 10.1242/dev.126.7.1397

PubMed ID: 11509834

Title: The Krox-20 null mutation differentially affects the development of masticatory muscles.

PubMed ID: 11509834

DOI: 10.1159/000048703

PubMed ID: 11823429

Title: Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain.

PubMed ID: 11823429

DOI: 10.1093/emboj/21.3.365

PubMed ID: 16054051

Title: Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms.

PubMed ID: 16054051

DOI: 10.1016/j.cmet.2004.12.009

PubMed ID: 17938205

Title: An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer.

PubMed ID: 17938205

DOI: 10.1128/mcb.00866-07

PubMed ID: 19651900

Title: The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.

PubMed ID: 19651900

DOI: 10.1128/mcb.00407-09

PubMed ID: 28576496

Title: Identification of zinc finger transcription factor EGR2 as a novel acetylated protein.

PubMed ID: 28576496

DOI: 10.1016/j.bbrc.2017.05.170

PubMed ID: 31852952

Title: A de novo EGR2 variant, c.1232A > G p.Asp411Gly, causes severe early-onset Charcot-Marie-Tooth Neuropathy Type 3 (Dejerine-Sottas Neuropathy).

PubMed ID: 31852952

DOI: 10.1038/s41598-019-55875-4

Sequence Information:

  • Length: 470
  • Mass: 49819
  • Checksum: 67712733C77960F0
  • Sequence:
  • MMTAKAVDKI PVTLSGFMHQ LPDSLYPVED LAASSVTIFP NGELGGPFDQ MNGVAGDGMI 
    NIDMTGEKRP LDLPYPSSFA PISAPRNQTF TYMGKFSIDP QYPGASCYPE GIINIVSAGI 
    LQGVTPPAST TASSSVTSAS PNPLATGPLG VCTMSQTQPE LDHLYSPPPP PPPYSGCTGD 
    LYQDPSAFLS PPSTTSTSSL AYQPPPSYPS PKPAMDPGLI PMIPDYPGFF PSPCQRDPHG 
    AAGPDRKPFP CPLDSLRVPP PLTPLSTIRN FTLGGPGAGV TGPGASGGGE GPRLPGSGSA 
    AVTATPYNPH HLPLRPILRP RKYPNRPSKT PVHERPYPCP AEGCDRRFSR SDELTRHIRI 
    HTGHKPFQCR ICMRNFSRSD HLTTHIRTHT GEKPFACDYC GRKFARSDER KRHTKIHLRQ 
    KERKSSAPSA PPSAQSSASG PGGSQAGGSL CGNSAIGGPL ASCTSRTRTP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.