Details for: Eif4ebp2

Gene ID: 13688

Symbol: Eif4ebp2

Ensembl ID: ENSMUSG00000020091

Description: eukaryotic translation initiation factor 4E binding protein 2

Associated with

Other Information

Genular Protein ID: 889795577

Symbol: 4EBP2_MOUSE

Name: N/A

UniProtKB Accession Codes:

P70445

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 15 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 3 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8939971

Title: Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes.

PubMed ID: 8939971

DOI: 10.1074/jbc.271.47.30199

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16237163

Title: The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampus.

PubMed ID: 16237163

DOI: 10.1523/jneurosci.2423-05.2005

PubMed ID: 17273556

Title: Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.

PubMed ID: 17273556

DOI: 10.1172/jci29528

PubMed ID: 17029989

Title: Behavioral alterations in mice lacking the translation repressor 4E-BP2.

PubMed ID: 17029989

DOI: 10.1016/j.nlm.2006.08.012

PubMed ID: 18515545

Title: Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs.

PubMed ID: 18515545

DOI: 10.1261/rna.950608

PubMed ID: 19175792

Title: Impaired myelopoiesis in mice lacking the repressors of translation initiation, 4E-BP1 and 4E-BP2.

PubMed ID: 19175792

DOI: 10.1111/j.1365-2567.2008.02981.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20424163

Title: Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain.

PubMed ID: 20424163

DOI: 10.1074/jbc.m110.120774

PubMed ID: 20347422

Title: Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission.

PubMed ID: 20347422

DOI: 10.1016/j.molcel.2010.02.022

PubMed ID: 24139800

Title: mTORC1 targets the translational repressor 4E-BP2, but not S6 kinase 1/2, to regulate neural stem cell self-renewal in vivo.

PubMed ID: 24139800

DOI: 10.1016/j.celrep.2013.09.017

PubMed ID: 23184952

Title: Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor.

PubMed ID: 23184952

DOI: 10.1074/jbc.m112.402461

PubMed ID: 23172145

Title: Autism-related deficits via dysregulated eIF4E-dependent translational control.

PubMed ID: 23172145

DOI: 10.1038/nature11628

Sequence Information:

  • Length: 120
  • Mass: 12898
  • Checksum: 0A1ACC082583F769
  • Sequence:
    • MSASAGGSHQ PSQSRAIPTR TVAISDAAQL PQDYCTTPGG TLFSTTPGGT RIIYDRKFLL 
DRRNSPMAQT PPCHLPNIPG VTSPGALIED SKVEVNNLNN LNNHDRKHAV GDEAQFEMDI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.