Details for: CPOX

Gene ID: 1371

Symbol: CPOX

Ensembl ID: ENSG00000080819

Description: coproporphyrinogen oxidase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 48.9664
    Cell Significance Index: -12.4200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 32.5284
    Cell Significance Index: -13.4000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 27.4929
    Cell Significance Index: -12.9800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 5.3976
    Cell Significance Index: -6.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.3694
    Cell Significance Index: -11.7100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.3401
    Cell Significance Index: -13.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.3805
    Cell Significance Index: -5.2100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7589
    Cell Significance Index: 45.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7253
    Cell Significance Index: 78.9000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.6623
    Cell Significance Index: 19.4500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6325
    Cell Significance Index: 102.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5442
    Cell Significance Index: 109.1700
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.4703
    Cell Significance Index: 7.5500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4608
    Cell Significance Index: 10.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4380
    Cell Significance Index: 12.6200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.4201
    Cell Significance Index: 2.6100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4032
    Cell Significance Index: 6.9100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3621
    Cell Significance Index: 25.0400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.3112
    Cell Significance Index: 8.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2643
    Cell Significance Index: 52.4500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2336
    Cell Significance Index: 127.5900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2248
    Cell Significance Index: 4.8700
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.2215
    Cell Significance Index: 1.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2188
    Cell Significance Index: 9.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2073
    Cell Significance Index: 74.3400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1999
    Cell Significance Index: 19.7700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1803
    Cell Significance Index: 34.3200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1668
    Cell Significance Index: 4.4700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1657
    Cell Significance Index: 149.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1589
    Cell Significance Index: 21.8200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1537
    Cell Significance Index: 5.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1171
    Cell Significance Index: 5.3100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1167
    Cell Significance Index: 2.4200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1036
    Cell Significance Index: 5.3800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0843
    Cell Significance Index: 1.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0809
    Cell Significance Index: 14.5900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0794
    Cell Significance Index: 1.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0714
    Cell Significance Index: 31.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0615
    Cell Significance Index: 1.7200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0544
    Cell Significance Index: 1.3600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0418
    Cell Significance Index: 5.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0293
    Cell Significance Index: 1.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0232
    Cell Significance Index: 1.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0047
    Cell Significance Index: -8.8300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0065
    Cell Significance Index: -12.0500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0080
    Cell Significance Index: -12.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0091
    Cell Significance Index: -6.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0096
    Cell Significance Index: -12.9900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0125
    Cell Significance Index: -9.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0135
    Cell Significance Index: -1.7300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0142
    Cell Significance Index: -9.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0162
    Cell Significance Index: -11.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0184
    Cell Significance Index: -3.1500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0215
    Cell Significance Index: -12.1100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0216
    Cell Significance Index: -0.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0217
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0226
    Cell Significance Index: -14.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0230
    Cell Significance Index: -10.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0303
    Cell Significance Index: -4.4000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0312
    Cell Significance Index: -1.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0331
    Cell Significance Index: -3.3800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0359
    Cell Significance Index: -10.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0401
    Cell Significance Index: -2.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0449
    Cell Significance Index: -5.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0478
    Cell Significance Index: -1.6600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0484
    Cell Significance Index: -1.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0536
    Cell Significance Index: -6.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0611
    Cell Significance Index: -3.4300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0612
    Cell Significance Index: -3.9500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0619
    Cell Significance Index: -7.0900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0622
    Cell Significance Index: -4.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0675
    Cell Significance Index: -14.2200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0718
    Cell Significance Index: -2.3000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0736
    Cell Significance Index: -9.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0751
    Cell Significance Index: -3.5300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0911
    Cell Significance Index: -1.5300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0930
    Cell Significance Index: -1.8200
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0945
    Cell Significance Index: -1.0700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1112
    Cell Significance Index: -2.9800
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1177
    Cell Significance Index: -1.5700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1245
    Cell Significance Index: -12.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1263
    Cell Significance Index: -3.3200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1275
    Cell Significance Index: -1.3200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1352
    Cell Significance Index: -10.0800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1353
    Cell Significance Index: -9.1000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1431
    Cell Significance Index: -2.0500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1467
    Cell Significance Index: -11.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1648
    Cell Significance Index: -10.1100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1677
    Cell Significance Index: -2.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1943
    Cell Significance Index: -10.2000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1957
    Cell Significance Index: -5.0000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2053
    Cell Significance Index: -6.5400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2214
    Cell Significance Index: -4.7000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2288
    Cell Significance Index: -7.4900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2296
    Cell Significance Index: -3.3900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2369
    Cell Significance Index: -3.5700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2409
    Cell Significance Index: -3.5600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2620
    Cell Significance Index: -5.1800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2656
    Cell Significance Index: -6.3700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2660
    Cell Significance Index: -9.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzymatic activity:** CPOX is a cytochrome P450 enzyme that catalyzes the oxidation of coproporphyrinogen III to protoporphyrin IX, a critical step in the heme biosynthetic pathway. 2. **Subcellular localization:** CPOX is primarily found in the cytosol and mitochondria, highlighting its involvement in both heme synthesis and cellular energy metabolism. 3. **Protein homodimerization:** CPOX can form homodimers, which may influence its enzymatic activity and cellular localization. 4. **Expression in various cell types:** CPOX is expressed in a wide range of cell types, including proerythroblasts, germ cells, promyelocytes, and immune cells, suggesting its involvement in cell differentiation, proliferation, and immune responses. **Pathways and Functions:** 1. **Heme biosynthetic process:** CPOX is a crucial enzyme in the heme biosynthetic pathway, responsible for the oxidation of coproporphyrinogen III to protoporphyrin IX. 2. **Heme b biosynthetic process:** CPOX is also involved in the biosynthesis of heme B, a minor heme isoform. 3. **Heme biosynthesis:** CPOX plays a key role in the overall heme biosynthetic process, ensuring the proper production of heme. 4. **Cytoplasmic and mitochondrial processes:** CPOX is involved in various cytoplasmic and mitochondrial processes, including energy metabolism, cell differentiation, and proliferation. 5. **Immune responses:** CPOX has been implicated in immune responses, particularly in the context of heme biosynthesis and iron metabolism. **Clinical Significance:** 1. **Porphyrin disorders:** Mutations in the CPOX gene can lead to porphyria cutanea tarda (PCT), a disorder characterized by skin blistering and scarring. 2. **Heme-related disorders:** Abnormalities in heme biosynthesis, including those involving CPOX, can contribute to disorders such as hemolytic anemia and iron overload. 3. **Neurological disorders:** CPOX has been linked to neurological disorders, including Parkinson's disease and Alzheimer's disease, possibly due to its role in energy metabolism and iron homeostasis. 4. **Cancer and immunology:** CPOX has been implicated in cancer and immunological disorders, highlighting the need for further research into its role in these contexts. In conclusion, coproporphyrinogen oxidase (CPOX) is a multifaceted enzyme involved in heme biosynthesis, energy metabolism, and immune responses. Its significant expression in various cell types and its clinical significance underscore the importance of further research into its role in human health and disease.

Genular Protein ID: 3072594842

Symbol: HEM6_HUMAN

Name: N/A

UniProtKB Accession Codes:

P36551 A8K275 B4DSD5 Q14060 Q53F08 Q8IZ45 Q96AF3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 16 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7987309

Title: Coproporphyrinogen oxidase: gene organization and description of a mutation leading to exon 6 skipping.

PubMed ID: 7987309

DOI: 10.1093/hmg/3.8.1325

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8286403

Title: Molecular cloning, sequencing and expression of cDNA encoding human coproporphyrinogen oxidase.

PubMed ID: 8286403

DOI: 10.1016/0005-2728(94)90083-3

PubMed ID: 8159699

Title: Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.

PubMed ID: 8159699

DOI: 10.1073/pnas.91.8.3024

PubMed ID: 12862310

Title: The long, but not the short, presequence of human coproporphyrinogen oxidase is essential for its import and sorting to mitochondria.

PubMed ID: 12862310

DOI: 10.1620/tjem.200.39

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 8012360

Title: Homozygous hereditary coproporphyria caused by an arginine to tryptophan substitution in coproporphyrinogen oxidase and common intragenic polymorphisms.

PubMed ID: 8012360

DOI: 10.1093/hmg/3.3.477

PubMed ID: 21103937

Title: Harderoporphyria due to homozygosity for coproporphyrinogen oxidase missense mutation H327R.

PubMed ID: 21103937

DOI: 10.1007/s10545-010-9237-9

PubMed ID: 16176984

Title: Structural basis of hereditary coproporphyria.

PubMed ID: 16176984

DOI: 10.1073/pnas.0506557102

PubMed ID: 7849704

Title: Characterization and expression of cDNA encoding coproporphyrinogen oxidase from a patient with hereditary coproporphyria.

PubMed ID: 7849704

DOI: 10.1093/hmg/3.10.1807

PubMed ID: 7757079

Title: A molecular defect in coproporphyrinogen oxidase gene causing harderoporphyria, a variant form of hereditary coproporphyria.

PubMed ID: 7757079

DOI: 10.1093/hmg/4.2.275

PubMed ID: 9048920

Title: A novel missense mutation in exon 4 of the human coproporphyrinogen oxidase gene in two patients with hereditary coproporphyria.

PubMed ID: 9048920

DOI: 10.1007/s004390050338

PubMed ID: 8990017

Title: Three novel mutations in the coproporphyrinogen oxidase gene.

PubMed ID: 8990017

DOI: 10.1002/(sici)1098-1004(1997)9:1<78::aid-humu17>3.0.co;2-m

PubMed ID: 9298818

Title: Hereditary coproporphyria: exon screening by heteroduplex analysis detects three novel mutations in the coproporphyrinogen oxidase gene.

PubMed ID: 9298818

DOI: 10.1002/(sici)1098-1004(1997)10:3<196::aid-humu3>3.0.co;2-h

PubMed ID: 9843038

Title: Identification of a novel mutation of the CPO gene in a Japanese hereditary coproporphyria family.

PubMed ID: 9843038

DOI: 10.1002/(sici)1096-8628(19981116)80:3<204::aid-ajmg4>3.3.co;2-7

PubMed ID: 9888388

Title: Systematic analysis of coproporphyrinogen oxidase gene defects in hereditary coproporphyria and mutation update.

PubMed ID: 9888388

DOI: 10.1002/(sici)1098-1004(1999)13:1<44::aid-humu5>3.0.co;2-q

PubMed ID: 12181641

Title: Two novel mutations and coexistence of the 991C>T and the 1339C>T mutation on a single allele in the coproporphyrinogen oxidase gene in Swedish patients with hereditary coproporphyria.

PubMed ID: 12181641

DOI: 10.1007/s100380200059

PubMed ID: 15896662

Title: Biochemical and genetic characterization of four cases of hereditary coproporphyria in Spain.

PubMed ID: 15896662

DOI: 10.1016/j.ymgme.2004.12.012

PubMed ID: 16398658

Title: Dual gene defects involving delta-aminolaevulinate dehydratase and coproporphyrinogen oxidase in a porphyria patient.

PubMed ID: 16398658

DOI: 10.1111/j.1365-2141.2005.05852.x

Sequence Information:

  • Length: 454
  • Mass: 50152
  • Checksum: 6EC3D15FD8FD86B5
  • Sequence:
    • MALQLGRLSS GPCWLVARGG CGGPRAWSQC GGGGLRAWSQ RSAAGRVCRP PGPAGTEQSR 
GLGHGSTSRG GPWVGTGLAA ALAGLVGLAT AAFGHVQRAE MLPKTSGTRA TSLGRPEEEE 
DELAHRCSSF MAPPVTDLGE LRRRPGDMKT KMELLILETQ AQVCQALAQV DGGANFSVDR 
WERKEGGGGI SCVLQDGCVF EKAGVSISVV HGNLSEEAAK QMRSRGKVLK TKDGKLPFCA 
MGVSSVIHPK NPHAPTIHFN YRYFEVEEAD GNKQWWFGGG CDLTPTYLNQ EDAVHFHRTL 
KEACDQHGPD LYPKFKKWCD DYFFIAHRGE RRGIGGIFFD DLDSPSKEEV FRFVQSCARA 
VVPSYIPLVK KHCDDSFTPQ EKLWQQLRRG RYVEFNLLYD RGTKFGLFTP GSRIESILMS 
LPLTARWEYM HSPSENSKEA EILEVLRHPR DWVR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.