Genular: Defining Cellular Identity and Function

Details for: Emd

Gene ID: 13726

Symbol: Emd

Ensembl ID: ENSMUSG00000001964

Description: emerin

Associated with

Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Depolymerization of the nuclear lamina
(R-MMU-4419969)
Initiation of nuclear envelope (ne) reformation
(R-MMU-2995383)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
(R-MMU-9609523)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prophase
(R-MMU-68875)
M phase
(R-MMU-68886)
Nuclear envelope (ne) reassembly
(R-MMU-2995410)
Nuclear envelope breakdown
(R-MMU-2980766)
Protein localization
(R-MMU-9609507)
Rac1 gtpase cycle
(R-MMU-9013149)
Rac2 gtpase cycle
(R-MMU-9013404)
Rac3 gtpase cycle
(R-MMU-9013423)
Rhod gtpase cycle
(R-MMU-9013405)
Rhog gtpase cycle
(R-MMU-9013408)
Rho gtpase cycle
(R-MMU-9012999)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Actin binding
(GO:0003779)
Beta-tubulin binding
(GO:0048487)
Cellular response to growth factor stimulus
(GO:0071363)
Cortical endoplasmic reticulum
(GO:0032541)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum
(GO:0005783)
Membrane
(GO:0016020)
Microtubule
(GO:0005874)
Negative regulation of canonical wnt signaling pathway
(GO:0090090)
Negative regulation of fibroblast proliferation
(GO:0048147)
Nuclear envelope
(GO:0005635)
Nuclear inner membrane
(GO:0005637)
Nuclear lamina
(GO:0005652)
Nuclear membrane
(GO:0031965)
Nuclear membrane organization
(GO:0071763)
Nuclear outer membrane
(GO:0005640)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of protein export from nucleus
(GO:0046827)
Protein binding
(GO:0005515)
Regulation of canonical wnt signaling pathway
(GO:0060828)
Skeletal muscle cell differentiation
(GO:0035914)
Spindle
(GO:0005819)
Spindle pole centrosome
(GO:0031616)
Tmem240-body
(GO:0160045)

Other Information

Proteins

Emerin

Genular Protein ID: 1251175772

Symbol: EMD_MOUSE

Name: Emerin

UniProtKB Accession Codes:

O08579 Q3TIH6 Q3UJP3

Database IDs:

Citations:

PubMed ID: 9107678

Title: Isolation and characterization of the complete mouse emerin gene.

PubMed ID: 9107678

DOI: 10.1007/s003359900435

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10579712

Title: Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy.

PubMed ID: 10579712

DOI: 10.1083/jcb.147.5.913

PubMed ID: 18230648

Title: LUMA interacts with emerin and influences its distribution at the inner nuclear membrane.

PubMed ID: 18230648

DOI: 10.1242/jcs.019281

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19933576

Title: Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.

PubMed ID: 19933576

DOI: 10.1074/jbc.m109.071910

PubMed ID: 32923640

Title: The NEMP family supports metazoan fertility and nuclear envelope stiffness.

PubMed ID: 32923640

DOI: 10.1126/sciadv.abb4591

Sequence Information:

Length: 259
Mass: 29436
Checksum: 645B021541063502
Sequence:

MDDYAVLSDT ELAAVLRQYN IPHGPIVGST RKLYEKKIFE YETQRRRLLP PNSSSSSFSY 
QFSDLDSAAV DSDMYDLPKK EDALLYQSKD YNDDYYEESY LTTKTYGEPE SVGMSKSFRQ 
PGTSLVDADT FHHQVRDDIF SSLEEEGKDR ERLIYGQDSA YQSIAHYRPI SNVSRSSLGL 
SYYPTSSTSS VSSSSSSPSS WLTRRAIRPE KQAPAAALGQ DRQVPLWGQL LLFLVFAAFL 
LFVYYSIQAE EGNPFWMDP

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Emd

Associated with

Other Information

Isolation and characterization of the complete mouse emerin gene. PubMed ID: 9107678

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. PubMed ID: 10579712

LUMA interacts with emerin and influences its distribution at the inner nuclear membrane. PubMed ID: 18230648

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. PubMed ID: 19131326

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes. PubMed ID: 19933576

The NEMP family supports metazoan fertility and nuclear envelope stiffness. PubMed ID: 32923640