Details for: CPT1A

Gene ID: 1374

Symbol: CPT1A

Ensembl ID: ENSG00000110090

Description: carnitine palmitoyltransferase 1A

Associated with

Other Information

Genular Protein ID: 4289844490

Symbol: CPT1A_HUMAN

Name: Carnitine O-palmitoyltransferase 1, liver isoform

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7892212

Title: Human liver mitochondrial carnitine palmitoyltransferase I: characterization of its cDNA and chromosomal localization and partial analysis of the gene.

PubMed ID: 7892212

DOI: 10.1073/pnas.92.6.1984

PubMed ID: 12189492

Title: Organization of the human liver carnitine palmitoyltransferase 1 gene (CPT1A) and identification of novel mutations in hypoketotic hypoglycaemia.

PubMed ID: 12189492

DOI: 10.1007/s00439-002-0752-0

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16651524

Title: The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis.

PubMed ID: 16651524

DOI: 10.1073/pnas.0602205103

PubMed ID: 16271724

Title: An intronic peroxisome proliferator-activated receptor-binding sequence mediates fatty acid induction of the human carnitine palmitoyltransferase 1A.

PubMed ID: 16271724

DOI: 10.1016/j.jmb.2005.09.097

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 14711372

Title: Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.

PubMed ID: 14711372

DOI: 10.1042/bj20031373

PubMed ID: 21990363

Title: An environment-dependent structural switch underlies the regulation of carnitine palmitoyltransferase 1A.

PubMed ID: 21990363

DOI: 10.1074/jbc.m111.306951

PubMed ID: 9691089

Title: Molecular basis of hepatic carnitine palmitoyltransferase I deficiency.

PubMed ID: 9691089

DOI: 10.1172/jci2927

PubMed ID: 11441142

Title: Molecular characterization of L-CPT I deficiency in six patients: insights into function of the native enzyme.

PubMed ID: 11441142

PubMed ID: 11350182

Title: Molecular and enzymatic characterization of a unique carnitine palmitoyltransferase 1A mutation in the Hutterite community.

PubMed ID: 11350182

DOI: 10.1006/mgme.2001.3176

PubMed ID: 12111367

Title: Expression analysis of two mutations in carnitine palmitoyltransferase IA deficiency.

PubMed ID: 12111367

DOI: 10.1007/s100380200047

PubMed ID: 14517221

Title: Functional and structural basis of carnitine palmitoyltransferase 1A deficiency.

PubMed ID: 14517221

DOI: 10.1074/jbc.m310130200

PubMed ID: 15669684

Title: Successful long-term treatment of hepatic carnitine palmitoyltransferase I deficiency and a novel mutation.

PubMed ID: 15669684

DOI: 10.1023/b:boli.0000042979.42120.55

PubMed ID: 15110323

Title: Novel mutations in CPT 1A define molecular heterogeneity of hepatic carnitine palmitoyltransferase I deficiency.

PubMed ID: 15110323

DOI: 10.1016/j.ymgme.2004.02.004

Sequence Information:

  • Length: 773
  • Mass: 88368
  • Checksum: E5DC9141B6301947
  • Sequence:
  • MAEAHQAVAF QFTVTPDGID LRLSHEALRQ IYLSGLHSWK KKFIRFKNGI ITGVYPASPS 
    SWLIVVVGVM TTMYAKIDPS LGIIAKINRT LETANCMSSQ TKNVVSGVLF GTGLWVALIV 
    TMRYSLKVLL SYHGWMFTEH GKMSRATKIW MGMVKIFSGR KPMLYSFQTS LPRLPVPAVK 
    DTVNRYLQSV RPLMKEEDFK RMTALAQDFA VGLGPRLQWY LKLKSWWATN YVSDWWEEYI 
    YLRGRGPLMV NSNYYAMDLL YILPTHIQAA RAGNAIHAIL LYRRKLDREE IKPIRLLGST 
    IPLCSAQWER MFNTSRIPGE ETDTIQHMRD SKHIVVYHRG RYFKVWLYHD GRLLKPREME 
    QQMQRILDNT SEPQPGEARL AALTAGDRVP WARCRQAYFG RGKNKQSLDA VEKAAFFVTL 
    DETEEGYRSE DPDTSMDSYA KSLLHGRCYD RWFDKSFTFV VFKNGKMGLN AEHSWADAPI 
    VAHLWEYVMS IDSLQLGYAE DGHCKGDINP NIPYPTRLQW DIPGECQEVI ETSLNTANLL 
    ANDVDFHSFP FVAFGKGIIK KCRTSPDAFV QLALQLAHYK DMGKFCLTYE ASMTRLFREG 
    RTETVRSCTT ESCDFVRAMV DPAQTVEQRL KLFKLASEKH QHMYRLAMTG SGIDRHLFCL 
    YVVSKYLAVE SPFLKEVLSE PWRLSTSQTP QQQVELFDLE NNPEYVSSGG GFGPVADDGY 
    GVSYILVGEN LINFHISSKF SCPETDSHRF GRHLKEAMTD IITLFGLSSN SKK

Genular Protein ID: 1016564899

Symbol: B2RAQ8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 773
  • Mass: 88340
  • Checksum: 90F7C3F49D627383
  • Sequence:
  • MAEAHQAVAF QFTVTPDGID LRLSHEALRQ IYLSGLHSWK KKFIRFKNGI ITGVYPASPS 
    SWLIVVVGVM TTMYAKIDPS LGIIAKINRT LETANCMSSQ TKNVVSGVLF GTGLWVALIV 
    TMRYSLKVLL SYHGWMFTEH GKMSRATKIW MGMVKIFSGR KPMLYSFQTS LPRLPVPAVK 
    DTVNRYLQSV RPLMKEEDFK RMTALAQDFA VGLGPRLQWY LKLKSWWATN YVSDWWEEYI 
    YLRGRGPLMV NSNYYAMDLL YILPTHIQAA RAGNAIHAIL LYRRKLDQEE IKPIRLLGST 
    IPLCSAQWER MFNTSRIPGE ETDTIQHMRD SKHIVVYHRG RYFKVWLYHD GRLLKPREME 
    QQMQRILDNT SEPQPGEARL AALTAGDRVP WARCRQAYFG RGKNKQSLDA VEKAAFFVTL 
    DETEEGYRSE DPDTSMDSYA KSLLHGRCYD RWFDKSFTFV VFKNGKMGLN AEHSWADAPI 
    VAHLWEYVMS IDSLQLGYAE DGHCKGDINP NIPYPTRLQW DIPGECQEVI ETSLNTANLL 
    ANDVDFHSFP FVAFGKGIIK KCRTSPDAFV QLALQLAHYK DMGKFCLTYE ASMTRLFREG 
    RTETVRSCTT ESCDFVRAMV DPAQTVEQRL KLFKLASEKH QHMYRLAMTG SGIDRHLFCL 
    YVVSKYLAVE SPFLKEVLSE PWRLSTSQTP QQQVELFDLE NNPEYVSSGG GFGPVADDGY 
    GVSYILVGEN LINFHISSKF SCPETDSHRF GRHLKEAMTD IITLFGLSSN SKK

Genular Protein ID: 91059581

Symbol: Q8WZ48_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 28
  • Mass: 3190
  • Checksum: 5CBBD9F207F78D3D
  • Sequence:
  • DSHRFGRHLK EAMTDIITLF GLSSNSKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.