Details for: CR1

Gene ID: 1378

Symbol: CR1

Ensembl ID: ENSG00000203710

Description: complement C3b/C4b receptor 1 (Knops blood group)

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 1.92
    Marker Score: 2076
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6
    Marker Score: 1162
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.48
    Marker Score: 169266
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4
    Marker Score: 1391
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.25
    Marker Score: 847
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.16
    Marker Score: 480
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4804
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.08
    Marker Score: 496
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251796
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71814
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48039
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 502
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 456
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5306.5
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 368
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2737
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 0.9
    Marker Score: 850
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.89
    Marker Score: 320
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5282
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.87
    Marker Score: 48578
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.85
    Marker Score: 644
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.83
    Marker Score: 1683.5
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 602
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1263
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 704
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.77
    Marker Score: 285
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 390
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 0.72
    Marker Score: 645
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.71
    Marker Score: 712
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.71
    Marker Score: 455
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 0.71
    Marker Score: 519
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7
    Marker Score: 2084
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 176
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.68
    Marker Score: 304
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.59
    Marker Score: 1696
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.55
    Marker Score: 6383
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.54
    Marker Score: 328
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.54
    Marker Score: 171
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.52
    Marker Score: 976.5
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.5
    Marker Score: 1244
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.49
    Marker Score: 3235
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 0.48
    Marker Score: 845
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.48
    Marker Score: 246
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.47
    Marker Score: 7395
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.47
    Marker Score: 748
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.46
    Marker Score: 442
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 0.41
    Marker Score: 252
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.4
    Marker Score: 440
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.39
    Marker Score: 127
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 0.39
    Marker Score: 381
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.38
    Marker Score: 235
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.38
    Marker Score: 226
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 0.37
    Marker Score: 85
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.36
    Marker Score: 128
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.36
    Marker Score: 199
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.36
    Marker Score: 466
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.36
    Marker Score: 217
  • Cell Name: centroblast (CL0009112)
    Fold Change: 0.36
    Marker Score: 175
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 0.35
    Marker Score: 687
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.35
    Marker Score: 352
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 0.34
    Marker Score: 81
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.34
    Marker Score: 164
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.33
    Marker Score: 1354
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.32
    Marker Score: 112
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 0.32
    Marker Score: 675
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.31
    Marker Score: 728
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 0.3
    Marker Score: 347
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 0.3
    Marker Score: 1816
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.3
    Marker Score: 538
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.29
    Marker Score: 128
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 0.28
    Marker Score: 677
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.28
    Marker Score: 74
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.27
    Marker Score: 156
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.27
    Marker Score: 69
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.26
    Marker Score: 187
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.26
    Marker Score: 90
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.25
    Marker Score: 126
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.25
    Marker Score: 63
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.24
    Marker Score: 141
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.24
    Marker Score: 119
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.23
    Marker Score: 111
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.23
    Marker Score: 65
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.22
    Marker Score: 2091
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 0.22
    Marker Score: 147
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.22
    Marker Score: 126
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 74
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.21
    Marker Score: 142
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.21
    Marker Score: 5477
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.21
    Marker Score: 289
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.21
    Marker Score: 162
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.21
    Marker Score: 75
  • Cell Name: follicular dendritic cell (CL0000442)
    Fold Change: 0.2
    Marker Score: 73
  • Cell Name: promonocyte (CL0000559)
    Fold Change: 0.2
    Marker Score: 126
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.19
    Marker Score: 94
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.19
    Marker Score: 129
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.18
    Marker Score: 442
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.18
    Marker Score: 77

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Other Information

**Key characteristics:** * CR1 is a glycoprotein that is composed of two immunoglobulin heavy chains and two immunoglobulin light chains. * It is expressed on a variety of cell types, including endothelial cells, macrophages, dendritic cells, and lymphocytes. * CR1 is a transmembrane protein that is located on the surface of endothelial cells and macrophages. **Pathways and functions:** * CR1 is a key component of the complement cascade, a complex network of proteins that is involved in the immune response. * The complement cascade is activated by the binding of antibodies to antigens on the surface of pathogens. * Once activated, the complement cascade can lead to the formation of membrane attack complexes, which are protein complexes that can kill pathogens. * CR1 is a key component of the complement cascade, and its absence leads to a deficiency in the complement cascade and an increased susceptibility to infection. **Clinical significance:** CR1 is a clinically significant protein because it is involved in the pathogenesis of a number of diseases. For example, mutations in the CR1 gene have been linked to the development of autoimmune disorders such as systemic sclerosis and lupus. CR1 is also involved in the pathogenesis of some types of cancer. **Additional notes:** * CR1 is a highly conserved protein, with a similar protein found in other mammals. * The CR1 gene is located on chromosome 1q21. * CR1 is a protein that is expressed in high levels in healthy individuals. * In diseases such as autoimmune disorders and cancer, the expression of CR1 is often increased.

Genular Protein ID: 2037846987

Symbol: CR1_HUMAN

Name: Complement receptor type 1

UniProtKB Accession Codes:

P17927 Q16744 Q16745 Q5SR43 Q5SR45 Q9UQV2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 83 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 1 GeneCards 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NIAGADS 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 7 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2972794

Title: Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.

PubMed ID: 2972794

DOI: 10.1084/jem.168.5.1699

PubMed ID: 8245463

Title: Structure of the gene for the F allele of complement receptor type 1 and sequence of the coding region unique to the S allele.

PubMed ID: 8245463

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 2564414

Title: Structure of the human CR1 gene. Molecular basis of the structural and quantitative polymorphisms and identification of a new CR1-like allele.

PubMed ID: 2564414

DOI: 10.1084/jem.169.3.847

PubMed ID: 2971757

Title: Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional unit and prediction of a secreted form of complement receptor type 1.

PubMed ID: 2971757

DOI: 10.1084/jem.168.4.1255

PubMed ID: 2951479

Title: Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.

PubMed ID: 2951479

DOI: 10.1084/jem.165.4.1095

PubMed ID: 2933745

Title: Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b.

PubMed ID: 2933745

DOI: 10.1073/pnas.82.22.7711

PubMed ID: 6233222

Title: C3b receptor (CR1) on erythrocytes in various diseases.

PubMed ID: 6233222

DOI: 10.1016/0165-2478(84)90089-0

PubMed ID: 2963069

Title: The clearance of tetanus toxoid/anti-tetanus toxoid immune complexes from the circulation of humans. Complement- and erythrocyte complement receptor 1-dependent mechanisms.

PubMed ID: 2963069

PubMed ID: 1385479

Title: Expression and localization of proteins of the complement system in human skin.

PubMed ID: 1385479

DOI: 10.1172/jci116080

PubMed ID: 1534036

Title: Distribution and quantitative expression of the complement receptor type 1 (CR1) on human peripheral blood T lymphocytes.

PubMed ID: 1534036

DOI: 10.1016/0008-8749(92)90277-v

PubMed ID: 8175757

Title: Analysis of the functional domains of complement receptor type 1 (C3b/C4b receptor; CD35) by substitution mutagenesis.

PubMed ID: 8175757

DOI: 10.1016/s0021-9258(17)36829-1

PubMed ID: 8706338

Title: Structural polymorphisms of complement receptor 1 (CR1) in systemic lupus erythematosus (SLE) patients and normal controls of three ethnic groups.

PubMed ID: 8706338

DOI: 10.1046/j.1365-2249.1996.d01-748.x

PubMed ID: 9324355

Title: Complement receptor type 1 (CR1, CD35) is a receptor for C1q.

PubMed ID: 9324355

DOI: 10.1016/s1074-7613(00)80356-8

PubMed ID: 14694201

Title: A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria.

PubMed ID: 14694201

DOI: 10.1073/pnas.0305306101

PubMed ID: 23416052

Title: Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.

PubMed ID: 23416052

DOI: 10.1016/j.celrep.2013.01.023

PubMed ID: 23460739

Title: Deciphering complement receptor type 1 interactions with recognition proteins of the lectin complement pathway.

PubMed ID: 23460739

DOI: 10.4049/jimmunol.1202451

PubMed ID: 25742728

Title: Complement receptor type 1 (CR1/CD35) expressed on activated human CD4+ T cells contributes to generation of regulatory T cells.

PubMed ID: 25742728

DOI: 10.1016/j.imlet.2015.02.009

PubMed ID: 29563915

Title: C1q and Mannose-Binding Lectin Interact with CR1 in the Same Region on CCP24-25 Modules.

PubMed ID: 29563915

DOI: 10.3389/fimmu.2018.00453

PubMed ID: 11313284

Title: Molecular identification of Knops blood group polymorphisms found in long homologous region D of complement receptor 1.

PubMed ID: 11313284

DOI: 10.1182/blood.v97.9.2879

PubMed ID: 11896343

Title: Expansion of the Knops blood group system and subdivision of Sl(a).

PubMed ID: 11896343

DOI: 10.1046/j.1537-2995.2002.00002.x

PubMed ID: 11955431

Title: Structure of the C3b binding site of CR1 (CD35), the immune adherence receptor.

PubMed ID: 11955431

DOI: 10.1016/s0092-8674(02)00672-4

Sequence Information:

  • Length: 2039
  • Mass: 223663
  • Checksum: FB01870F19D5E6DD
  • Sequence:
    • MGASSPRSPE PVGPPAPGLP FCCGGSLLAV VVLLALPVAW GQCNAPEWLP FARPTNLTDE 
FEFPIGTYLN YECRPGYSGR PFSIICLKNS VWTGAKDRCR RKSCRNPPDP VNGMVHVIKG 
IQFGSQIKYS CTKGYRLIGS SSATCIISGD TVIWDNETPI CDRIPCGLPP TITNGDFIST 
NRENFHYGSV VTYRCNPGSG GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP 
PNVENGILVS DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP 
PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY DLRGAASMRC TPQGDWSPAA PTCEVKSCDD 
FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF QLKGSSASYC VLAGMESLWN SSVPVCEQIF 
CPSPPVIPNG RHTGKPLEVF PFGKTVNYTC DPHPDRGTSF DLIGESTIRC TSDPQGNGVW 
SSPAPRCGIL GHCQAPDHFL FAKLKTQTNA SDFPIGTSLK YECRPEYYGR PFSITCLDNL 
VWSSPKDVCK RKSCKTPPDP VNGMVHVITD IQVGSRINYS CTTGHRLIGH SSAECILSGN 
AAHWSTKPPI CQRIPCGLPP TIANGDFIST NRENFHYGSV VTYRCNPGSG GRKVFELVGE 
PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS DNRSLFSLNE VVEFRCQPGF 
VMKGPRRVKC QALNKWEPEL PSCSRVCQPP PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY 
DLRGAASMRC TPQGDWSPAA PTCEVKSCDD FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF 
QLKGSSASYC VLAGMESLWN SSVPVCEQIF CPSPPVIPNG RHTGKPLEVF PFGKAVNYTC 
DPHPDRGTSF DLIGESTIRC TSDPQGNGVW SSPAPRCGIL GHCQAPDHFL FAKLKTQTNA 
SDFPIGTSLK YECRPEYYGR PFSITCLDNL VWSSPKDVCK RKSCKTPPDP VNGMVHVITD 
IQVGSRINYS CTTGHRLIGH SSAECILSGN TAHWSTKPPI CQRIPCGLPP TIANGDFIST 
NRENFHYGSV VTYRCNLGSR GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP 
PNVENGILVS DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP 
PEILHGEHTP SHQDNFSPGQ EVFYSCEPGY DLRGAASLHC TPQGDWSPEA PRCAVKSCDD 
FLGQLPHGRV LFPLNLQLGA KVSFVCDEGF RLKGSSVSHC VLVGMRSLWN NSVPVCEHIF 
CPNPPAILNG RHTGTPSGDI PYGKEISYTC DPHPDRGMTF NLIGESTIRC TSDPHGNGVW 
SSPAPRCELS VRAGHCKTPE QFPFASPTIP INDFEFPVGT SLNYECRPGY FGKMFSISCL 
ENLVWSSVED NCRRKSCGPP PEPFNGMVHI NTDTQFGSTV NYSCNEGFRL IGSPSTTCLV 
SGNNVTWDKK APICEIISCE PPPTISNGDF YSNNRTSFHN GTVVTYQCHT GPDGEQLFEL 
VGERSIYCTS KDDQVGVWSS PPPRCISTNK CTAPEVENAI RVPGNRSFFS LTEIIRFRCQ 
PGFVMVGSHT VQCQTNGRWG PKLPHCSRVC QPPPEILHGE HTLSHQDNFS PGQEVFYSCE 
PSYDLRGAAS LHCTPQGDWS PEAPRCTVKS CDDFLGQLPH GRVLLPLNLQ LGAKVSFVCD 
EGFRLKGRSA SHCVLAGMKA LWNSSVPVCE QIFCPNPPAI LNGRHTGTPF GDIPYGKEIS 
YACDTHPDRG MTFNLIGESS IRCTSDPQGN GVWSSPAPRC ELSVPAACPH PPKIQNGHYI 
GGHVSLYLPG MTISYICDPG YLLVGKGFIF CTDQGIWSQL DHYCKEVNCS FPLFMNGISK 
ELEMKKVYHY GDYVTLKCED GYTLEGSPWS QCQADDRWDP PLAKCTSRTH DALIVGTLSG 
TIFFILLIIF LSWIILKHRK GNNAHENPKE VAIHLHSQGG SSVHPRTLQT NEENSRVLP

Genular Protein ID: 285912690

Symbol: E9PDY4_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PDY4

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 InterPro 2 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 2 Pfam 1 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 1 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 2489
  • Mass: 272924
  • Checksum: B80E2DBF555E6B54
  • Sequence:
    • MGASSPRSPE PVGPPAPGLP FCCGGSLLAV VVLLALPVAW GQCNAPEWLP FARPTNLTDE 
FEFPIGTYLN YECRPGYSGR PFSIICLKNS VWTGAKDRCR RKSCRNPPDP VNGMVHVIKG 
IQFGSQIKYS CTKGYRLIGS SSATCIISGD TVIWDNETPI CDRIPCGLPP TITNGDFIST 
NRENFHYGSV VTYRCNPGSG GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP 
PNVENGILVS DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP 
PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY DLRGAASMRC TPQGDWSPAA PTCEVKSCDD 
FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF QLKGSSASYC VLAGMESLWN SSVPVCEQIF 
CPSPPVIPNG RHTGKPLEVF PFGKTVNYTC DPHPDRGTSF DLIGESTIRC TSDPQGNGVW 
SSPAPRCGIL GHCQAPDHFL FAKLKTQTNA SDFPIGTSLK YECRPEYYGR PFSITCLDNL 
VWSSPKDVCK RKSCKTPPDP VNGMVHVITD IQVGSRINYS CTTGHRLIGH SSAECILSGN 
AAHWSTKPPI CQRIPCGLPP TIANGDFIST NRENFHYGSV VTYRCNPGSG GRKVFELVGE 
PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS DNRSLFSLNE VVEFRCQPGF 
VMKGPRRVKC QALNKWEPEL PSCSRVCQPP PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY 
DLRGAASMRC TPQGDWSPAA PTCEVKSCDD FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF 
QLKGSSASYC VLAGMESLWN SSVPVCEQIF CPSPPVIPNG RHTGKPLEVF PFGKTVNYTC 
DPHPDRGTSF DLIGESTIRC TSDPQGNGVW SSPAPRCGIL GHCQAPDHFL FAKLKTQTNA 
SDFPIGTSLK YECRPEYYGR PFSITCLDNL VWSSPKDVCK RKSCKTPPDP VNGMVHVITD 
IQVGSRINYS CTTGHRLIGH SSAECILSGN AAHWSTKPPI CQRIPCGLPP TIANGDFIST 
NRENFHYGSV VTYRCNPGSG GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP 
PNVENGILVS DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP 
PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY DLRGAASMRC TPQGDWSPAA PTCEVKSCDD 
FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF QLKGSSASYC VLAGMESLWN SSVPVCEQIF 
CPSPPVIPNG RHTGKPLEVF PFGKAVNYTC DPHPDRGTSF DLIGESTIRC TSDPQGNGVW 
SSPAPRCGIL GHCQAPDHFL FAKLKTQTNA SDFPIGTSLK YECRPEYYGR PFSITCLDNL 
VWSSPKDVCK RKSCKTPPDP VNGMVHVITD IQVGSRINYS CTTGHRLIGH SSAECILSGN 
TAHWSTKPPI CQRIPCGLPP TIANGDFIST NRENFHYGSV VTYRCNLGSR GRKVFELVGE 
PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS DNRSLFSLNE VVEFRCQPGF 
VMKGPRRVKC QALNKWEPEL PSCSRVCQPP PEILHGEHTP SHQDNFSPGQ EVFYSCEPGY 
DLRGAASLHC TPQGDWSPEA PRCAVKSCDD FLGQLPHGRV LFPLNLQLGA KVSFVCDEGF 
RLKGSSVSHC VLVGMRSLWN NSVPVCEHIF CPNPPAILNG RHTGTPSGDI PYGKEISYTC 
DPHPDRGMTF NLIGESTIRC TSDPHGNGVW SSPAPRCELS VRAGHCKTPE QFPFASPTIP 
INDFEFPVGT SLNYECRPGY FGKMFSISCL ENLVWSSVED NCRRKSCGPP PEPFNGMVHI 
NTDTQFGSTV NYSCNEGFRL IGSPSTTCLV SGNNVTWDKK APICEIISCE PPPTISNGDF 
YSNNRTSFHN GTVVTYQCHT GPDGEQLFEL VGERSIYCTS KDDQVGVWSS PPPRCISTNK 
CTAPEVENAI RVPGNRSFFT LTEIIRFRCQ PGFVMVGSHT VQCQTNGRWG PKLPHCSRVC 
QPPPEILHGE HTLSHQDNFS PGQEVFYSCE PSYDLRGAAS LHCTPQGDWS PEAPRCTVKS 
CDDFLGQLPH GRVLLPLNLQ LGAKVSFVCD EGFRLKGRSA SHCVLAGMKA LWNSSVPVCE 
QIFCPNPPAI LNGRHTGTPF GDIPYGKEIS YACDTHPDRG MTFNLIGESS IRCTSDPQGN 
GVWSSPAPRC ELSVPAACPH PPKIQNGHYI GGHVSLYLPG MTISYICDPG YLLVGKGFIF 
CTDQGIWSQL DHYCKEVNCS FPLFMNGISK ELEMKKVYHY GDYVTLKCED GYTLEGSPWS 
QCQADDRWDP PLAKCTSRTH DALIVGTLSG TIFFILLIIF LSWIILKHRK GNNAHENPKE 
VAIHLHSQGG SSVHPRTLQT NEENSRVLP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.