Details for: CR2

Gene ID: 1380

Symbol: CR2

Ensembl ID: ENSG00000117322

Description: complement C3d receptor 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 8.4220
    Cell Significance Index: -1.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 5.3224
    Cell Significance Index: -1.3500
  • Cell Name: centroblast (CL0009112)
    Fold Change: 4.4641
    Cell Significance Index: 10.4200
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 3.7655
    Cell Significance Index: 11.6100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.5968
    Cell Significance Index: 188.3200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.3391
    Cell Significance Index: 42.8900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.1500
    Cell Significance Index: 17.3300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 1.0949
    Cell Significance Index: -1.3500
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.6871
    Cell Significance Index: 5.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.6733
    Cell Significance Index: 17.2000
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.6546
    Cell Significance Index: 9.3800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2945
    Cell Significance Index: 47.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2697
    Cell Significance Index: 16.1900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2444
    Cell Significance Index: 5.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2388
    Cell Significance Index: 5.9700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2130
    Cell Significance Index: 3.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1479
    Cell Significance Index: 14.6400
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 0.1239
    Cell Significance Index: 0.6200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1046
    Cell Significance Index: 1.6600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0803
    Cell Significance Index: 2.3700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0724
    Cell Significance Index: 7.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0596
    Cell Significance Index: 11.3500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0531
    Cell Significance Index: 1.1500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0462
    Cell Significance Index: 1.3300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0364
    Cell Significance Index: 1.6500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0353
    Cell Significance Index: 0.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0234
    Cell Significance Index: 1.6200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 0.0214
    Cell Significance Index: 0.2800
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.0171
    Cell Significance Index: 0.1200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0152
    Cell Significance Index: 0.4800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0146
    Cell Significance Index: 7.9900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0092
    Cell Significance Index: 0.1900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0070
    Cell Significance Index: 2.5300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0065
    Cell Significance Index: 1.3000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0018
    Cell Significance Index: 0.3500
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.0010
    Cell Significance Index: 0.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0009
    Cell Significance Index: 1.2700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0002
    Cell Significance Index: 0.3000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0004
    Cell Significance Index: -0.6200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.9100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0015
    Cell Significance Index: -0.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0018
    Cell Significance Index: -1.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0019
    Cell Significance Index: -1.3900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0023
    Cell Significance Index: -1.4500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0024
    Cell Significance Index: -0.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0026
    Cell Significance Index: -1.4500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0028
    Cell Significance Index: -2.0400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0029
    Cell Significance Index: -0.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0030
    Cell Significance Index: -1.8800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0032
    Cell Significance Index: -1.4700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0053
    Cell Significance Index: -0.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0057
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0069
    Cell Significance Index: -1.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0087
    Cell Significance Index: -1.2000
  • Cell Name: memory B cell (CL0000787)
    Fold Change: -0.0089
    Cell Significance Index: -0.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0104
    Cell Significance Index: -1.1900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0105
    Cell Significance Index: -1.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0122
    Cell Significance Index: -1.2700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0126
    Cell Significance Index: -1.6300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0135
    Cell Significance Index: -1.6600
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.0137
    Cell Significance Index: -0.1900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0140
    Cell Significance Index: -0.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0146
    Cell Significance Index: -0.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0149
    Cell Significance Index: -1.5200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0152
    Cell Significance Index: -0.3800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0176
    Cell Significance Index: -1.3500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0178
    Cell Significance Index: -1.2000
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: -0.0198
    Cell Significance Index: -0.1400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0212
    Cell Significance Index: -1.1000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0217
    Cell Significance Index: -0.7100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0223
    Cell Significance Index: -0.7800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0228
    Cell Significance Index: -0.7300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0242
    Cell Significance Index: -0.8500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0251
    Cell Significance Index: -1.4100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0258
    Cell Significance Index: -2.0400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0258
    Cell Significance Index: -1.3000
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0263
    Cell Significance Index: -0.3500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0266
    Cell Significance Index: -1.6300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0267
    Cell Significance Index: -1.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0275
    Cell Significance Index: -2.0500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0280
    Cell Significance Index: -1.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0293
    Cell Significance Index: -0.7700
  • Cell Name: naive B cell (CL0000788)
    Fold Change: -0.0294
    Cell Significance Index: -0.3100
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0310
    Cell Significance Index: -0.6300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0310
    Cell Significance Index: -0.8700
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0316
    Cell Significance Index: -0.4000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0316
    Cell Significance Index: -0.8600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0320
    Cell Significance Index: -0.6700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0325
    Cell Significance Index: -1.2300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0330
    Cell Significance Index: -1.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0339
    Cell Significance Index: -2.1900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0341
    Cell Significance Index: -0.4700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0344
    Cell Significance Index: -1.7900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0344
    Cell Significance Index: -0.7300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0345
    Cell Significance Index: -2.1200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0357
    Cell Significance Index: -1.6800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0364
    Cell Significance Index: -0.7200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0369
    Cell Significance Index: -0.7200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0396
    Cell Significance Index: -1.1300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0410
    Cell Significance Index: -0.6100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CR2 is a transmembrane receptor expressed on the surface of various cell types, including B cells, endothelial cells, and granulocytes. It is a member of the complement receptor family and is known to bind to complement components C3d and C3b, facilitating the regulation of complement activation and immune responses. CR2 is also involved in the regulation of B cell receptor signaling and has been implicated in the modulation of immune responses, including those in autoimmune and inflammatory conditions. **Pathways and Functions:** CR2 is involved in several key pathways, including: 1. **Complement activation regulation**: CR2 binds to complement components C3d and C3b, regulating the activation of the complement cascade and preventing excessive tissue damage. 2. **B cell differentiation and proliferation**: CR2 plays a crucial role in the differentiation and proliferation of B cells, influencing the development of immune responses. 3. **Immunoglobulin receptor binding**: CR2 interacts with immunoglobulins, modulating the signaling of B cell receptors and influencing immune responses. 4. **Negative regulation of complement activation**: CR2 can inhibit the activation of the complement cascade, preventing excessive tissue damage and promoting immune homeostasis. **Clinical Significance:** Dysregulation of CR2 has been implicated in various immune-related disorders, including: 1. **Autoimmune diseases**: CR2 dysfunction has been linked to autoimmune conditions such as rheumatoid arthritis, lupus, and multiple sclerosis. 2. **Inflammatory disorders**: CR2 has been implicated in inflammatory conditions, including atherosclerosis and cardiovascular disease. 3. **Cancer**: CR2 has been found to be overexpressed in certain types of cancer, including ovarian and breast cancer, where it may contribute to tumor progression and metastasis. In conclusion, CR2 is a critical component of the immune system, playing a pivotal role in regulating complement activation, B cell differentiation and proliferation, and immune responses. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of CR2 in maintaining immune homeostasis and preventing disease. Further research is needed to fully elucidate the mechanisms of CR2 function and its role in immune regulation. **Significantly expressed cells:** The significantly expressed cells of CR2 include: * Amacrine cell * Blood vessel endothelial cell * Colon goblet cell * Double negative thymocyte * Tonsil germinal center B cell * Centrocyte * Intestinal crypt stem cell of small intestine * Transit amplifying cell of colon * Granulocyte monocyte progenitor cell * Germinal center B cell **Proteins:** The protein associated with CR2 is CR2_HUMAN (Complement receptor type 2).

Genular Protein ID: 3025431652

Symbol: CR2_HUMAN

Name: Complement receptor type 2

UniProtKB Accession Codes:

P20023 C9JHD2 Q13866 Q14212 Q53EL2 Q5BKT9 Q5SR46 Q5SR48

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 24 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2563370

Title: Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor.

PubMed ID: 2563370

DOI: 10.1016/s0021-9258(18)94149-9

PubMed ID: 2832506

Title: Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins.

PubMed ID: 2832506

DOI: 10.1084/jem.167.3.1047

PubMed ID: 2827171

Title: Molecular cloning of the cDNA encoding the Epstein-Barr virus.C3d receptor (complement receptor type 2) of human b lymphocytes.

PubMed ID: 2827171

DOI: 10.1073/pnas.84.24.9194

PubMed ID: 10068037

Title: Evidence for a new transcript of the Epstein-Barr virus/C3d receptor (CR2, CD21) which is due to alternative exon usage.

PubMed ID: 10068037

DOI: 10.1016/s0161-5890(98)00098-4

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3016712

Title: Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement.

PubMed ID: 3016712

DOI: 10.1073/pnas.83.15.5639

PubMed ID: 8390533

Title: Characterization of the EBV/C3d receptor on the human Jurkat T cell line: evidence for a novel transcript.

PubMed ID: 8390533

PubMed ID: 2460635

Title: Soluble gp350/220 and deletion mutant glycoproteins block Epstein-Barr virus adsorption to lymphocytes.

PubMed ID: 2460635

DOI: 10.1128/jvi.62.12.4452-4464.1988

PubMed ID: 1702139

Title: Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.

PubMed ID: 1702139

DOI: 10.1084/jem.173.1.55

PubMed ID: 1708808

Title: Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.

PubMed ID: 1708808

DOI: 10.1084/jem.173.5.1083

PubMed ID: 1849076

Title: Epstein Barr virus/complement C3d receptor is an interferon alpha receptor.

PubMed ID: 1849076

DOI: 10.1002/j.1460-2075.1991.tb08025.x

PubMed ID: 1383329

Title: The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules.

PubMed ID: 1383329

PubMed ID: 1386409

Title: CD21 is a ligand for CD23 and regulates IgE production.

PubMed ID: 1386409

DOI: 10.1038/358505a0

PubMed ID: 7753047

Title: Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein.

PubMed ID: 7753047

DOI: 10.1016/0161-5890(95)00005-y

PubMed ID: 12938232

Title: Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human cell surface triggers pp60src and Akt-GSK3 activities upstream and downstream to PI 3-kinase, respectively.

PubMed ID: 12938232

DOI: 10.1002/eji.200324059

PubMed ID: 16172256

Title: The structure of human CD23 and its interactions with IgE and CD21.

PubMed ID: 16172256

DOI: 10.1084/jem.20050811

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 22035880

Title: Genetic CD21 deficiency is associated with hypogammaglobulinemia.

PubMed ID: 22035880

DOI: 10.1016/j.jaci.2011.09.027

PubMed ID: 30107486

Title: CD21 and FCRL5 form a receptor complex with robust B-cell activating capacity.

PubMed ID: 30107486

DOI: 10.1093/intimm/dxy052

PubMed ID: 11387479

Title: Structure of complement receptor 2 in complex with its C3d ligand.

PubMed ID: 11387479

DOI: 10.1126/science.1059118

PubMed ID: 12122212

Title: The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding.

PubMed ID: 12122212

DOI: 10.1073/pnas.162360499

PubMed ID: 16950392

Title: The 15 SCR flexible extracellular domains of human complement receptor type 2 can mediate multiple ligand and antigen interactions.

PubMed ID: 16950392

DOI: 10.1016/j.jmb.2006.08.012

PubMed ID: 21527715

Title: A crystal structure of the complex between human complement receptor 2 and its ligand C3d.

PubMed ID: 21527715

DOI: 10.1126/science.1201954

PubMed ID: 17360460

Title: Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus.

PubMed ID: 17360460

DOI: 10.1073/pnas.0609101104

Sequence Information:

  • Length: 1033
  • Mass: 112916
  • Checksum: 7D89DB4A07847E9A
  • Sequence:
    • MGAAGLLGVF LALVAPGVLG ISCGSPPPIL NGRISYYSTP IAVGTVIRYS CSGTFRLIGE 
KSLLCITKDK VDGTWDKPAP KCEYFNKYSS CPEPIVPGGY KIRGSTPYRH GDSVTFACKT 
NFSMNGNKSV WCQANNMWGP TRLPTCVSVF PLECPALPMI HNGHHTSENV GSIAPGLSVT 
YSCESGYLLV GEKIINCLSS GKWSAVPPTC EEARCKSLGR FPNGKVKEPP ILRVGVTANF 
FCDEGYRLQG PPSSRCVIAG QGVAWTKMPV CEEIFCPSPP PILNGRHIGN SLANVSYGSI 
VTYTCDPDPE EGVNFILIGE STLRCTVDSQ KTGTWSGPAP RCELSTSAVQ CPHPQILRGR 
MVSGQKDRYT YNDTVIFACM FGFTLKGSKQ IRCNAQGTWE PSAPVCEKEC QAPPNILNGQ 
KEDRHMVRFD PGTSIKYSCN PGYVLVGEES IQCTSEGVWT PPVPQCKVAA CEATGRQLLT 
KPQHQFVRPD VNSSCGEGYK LSGSVYQECQ GTIPWFMEIR LCKEITCPPP PVIYNGAHTG 
SSLEDFPYGT TVTYTCNPGP ERGVEFSLIG ESTIRCTSND QERGTWSGPA PLCKLSLLAV 
QCSHVHIANG YKISGKEAPY FYNDTVTFKC YSGFTLKGSS QIRCKADNTW DPEIPVCEKE 
TCQHVRQSLQ ELPAGSRVEL VNTSCQDGYQ LTGHAYQMCQ DAENGIWFKK IPLCKVIHCH 
PPPVIVNGKH TGMMAENFLY GNEVSYECDQ GFYLLGEKKL QCRSDSKGHG SWSGPSPQCL 
RSPPVTRCPN PEVKHGYKLN KTHSAYSHND IVYVDCNPGF IMNGSRVIRC HTDNTWVPGV 
PTCIKKAFIG CPPPPKTPNG NHTGGNIARF SPGMSILYSC DQGYLLVGEA LLLCTHEGTW 
SQPAPHCKEV NCSSPADMDG IQKGLEPRKM YQYGAVVTLE CEDGYMLEGS PQSQCQSDHQ 
WNPPLAVCRS RSLAPVLCGI AAGLILLTFL IVITLYVISK HRARNYYTDT SQKEAFHLEA 
REVYSVDPYN PAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.