Details for: Endog

Gene ID: 13804

Symbol: Endog

Ensembl ID: ENSMUSG00000015337

Description: endonuclease G

Associated with

Other Information

Genular Protein ID: 2576163806

Symbol: NUCG_MOUSE

Name: Endonuclease G, mitochondrial

UniProtKB Accession Codes:

O08600

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EC 1 EMBL 4 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 25 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 6 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 6 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 9324313

Title: Characterization and expression of the mouse endonuclease G gene.

PubMed ID: 9324313

DOI: 10.1089/dna.1997.16.1111

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 25355512

Title: Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination.

PubMed ID: 25355512

DOI: 10.1093/nar/gku1032

PubMed ID: 33473107

Title: Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.

PubMed ID: 33473107

DOI: 10.1038/s41467-020-20780-2

PubMed ID: 32192768

Title: Crystal structure of the mouse endonuclease G.

PubMed ID: 32192768

DOI: 10.1016/j.bbrc.2020.03.060

PubMed ID: 32095813

Title: Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.

PubMed ID: 32095813

DOI: 10.1093/nar/gkaa117

Sequence Information:

  • Length: 294
  • Mass: 32191
  • Checksum: 9F01FB1BC28B95D3
  • Sequence:
    • MRALRAGLTL ALGAGLGAAA EHWRRREGKA PGLLGRVPLL PVVAADLPAL PGGPAGGTGE 
LAKYGLPGVA QLRSRESYVL SYDPRTRGAL WVLEQLRPER LRGDGDRSAC DFREDDSVHA 
YHRATNADYR GSGFDRGHLA AAANHRWSQR AMDDTFYLSN VAPQVPHLNQ NAWNNLERYS 
RSLTRTYQNV YVCTGPLFLP RTEADGKSYV KYQVIGKNHV AVPTHFFKVL ILEAAGGQIE 
LRSYVMPNAP VDETIPLERF LVPIESIERA SGLLFVPNIL ARAGNLKAIT AGSK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.