Genular: Defining Cellular Identity and Function

Details for: Epha1

Gene ID: 13835

Symbol: Epha1

Ensembl ID: ENSMUSG00000029859

Description: Eph receptor A1

Associated with

Axon guidance
(R-MMU-422475)
Developmental biology
(R-MMU-1266738)
Eph-ephrin mediated repulsion of cells
(R-MMU-3928665)
Eph-ephrin signaling
(R-MMU-2682334)
Epha-mediated growth cone collapse
(R-MMU-3928663)
Nervous system development
(R-MMU-9675108)
Activation of gtpase activity
(GO:0090630)
Angiogenesis
(GO:0001525)
Atp binding
(GO:0005524)
Cell adhesion
(GO:0007155)
Cell surface receptor signaling pathway
(GO:0007166)
Ephrin receptor activity
(GO:0005003)
Ephrin receptor signaling pathway
(GO:0048013)
Fibronectin binding
(GO:0001968)
Kinase activity
(GO:0016301)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of protein kinase activity
(GO:0006469)
Nucleotide binding
(GO:0000166)
Peptidyl-tyrosine phosphorylation
(GO:0018108)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell-matrix adhesion
(GO:0001954)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of kinase activity
(GO:0033674)
Positive regulation of stress fiber assembly
(GO:0051496)
Protein autophosphorylation
(GO:0046777)
Protein binding
(GO:0005515)
Protein kinase activity
(GO:0004672)
Protein kinase binding
(GO:0019901)
Protein phosphorylation
(GO:0006468)
Protein tyrosine kinase activity
(GO:0004713)
Receptor complex
(GO:0043235)
Regulation of gtpase activity
(GO:0043087)
Substrate adhesion-dependent cell spreading
(GO:0034446)
Transferase activity
(GO:0016740)
Transmembrane-ephrin receptor activity
(GO:0005005)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)

Other Information

Proteins

Ephrin type-A receptor 1

Genular Protein ID: 1177112565

Symbol: EPHA1_MOUSE

Name: Ephrin type-A receptor 1

UniProtKB Accession Codes:

Q60750 Q8CED9 Q9ESJ2

Database IDs:

Citations:

PubMed ID: 11519828

Title: Characterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissues.

PubMed ID: 11519828

DOI: 10.3109/08977190109029118

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 8552593

Title: Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.

PubMed ID: 8552593

DOI: 10.1073/pnas.93.1.145

PubMed ID: 18802966

Title: Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice.

PubMed ID: 18802966

DOI: 10.1002/dvg.20434

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27446912

Title: Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis.

PubMed ID: 27446912

DOI: 10.3389/fcell.2016.00058

Sequence Information:

Length: 977
Mass: 108578
Checksum: AB78D6E6C8B2E7F4
Sequence:

MERRWPLGLA LLLLLLCAPL PPGARAEEVT LMDTSTAQGE LGWLLDPPET GWSEVQQMLN 
GTPLYMYQDC PIQEGGDTDH WLRSNWIYRG EEASRIYVEL QFTVRDCKSF PGGAGPLGCK 
ETFNLFYMES DQDVGIQLRR PLFQKVTTVA ADQSFTIRDL ASGSVKLNVE RCSLGHLTRR 
GLYLAFHNPG SCVALVSVRV FYQRCAETVH GLAHFPDTLP GPGGLVEVAG TCLSHAQISL 
GSSGTPRMHC SPDGEWLVPV GQCQCEPGYE ESSGNVGCTA CPTGFYRVDM NTLRCLKCPQ 
HSIAESEGST ICTCENGHYR APGEGPQVAC TRPPSAPQNL SFSTSGTQLS LRWEPPRDTG 
GRHDIRYSVE CLQCRGIAQD GGPCQPCGKG VHFSPAASGL TTSTVQVQGL EPYANYTFTV 
KSQNRVSGLD SSSPSSASLS INMGHAESLS GLSLKLVKKE PRQLELTWAG SRPRNPGGNL 
SYELHVLNQD EEWHQMVLEP RVLLTKLQPD TTYIVRVRTL TPLGPGPFSP DHEFRTSPPV 
SRSLTGGEIV AVIFGLLLGI ALLIGIYVFR SRRGQRQRQQ RQRERTTNVD REDKLWLKPY 
VDLQAYEDPA QGALDFAQEL DPAWLIVDTV IGEGEFGEVY RGALRLPSQD CKTVAIKTLK 
DTSPDGYWWN FLREATIMGQ FNHPHILRLE GVITKRKPIM IITEFMENGA LDAFLKERED 
QLAPGQLVAM LLGIASGMNC LSGHNYVHRD LAARNILVNQ NLCCKVSDFG LTRLLDDFDG 
TYETQGGKIP IRWTAPEAIA HRIFTTASDV WSFGIVMWEV LSFGDKPYGE MSNQEVMKSI 
EDGYRLPPPV DCPAPLYELM KNCWAYDRAR RPHFLQLQAH LEQLLTDPHS LRTIANFDPR 
VTLRLPSLSG SDGIPYRSVS EWLESIRMKR YILHFRSAGL DTMECVLELT AEDLTQMGIT 
LPGHQKRILC SIQGFKD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Epha1

Associated with

Other Information

Characterization of the Epha1 receptor tyrosine kinase: expression in epithelial tissues. PubMed ID: 11519828

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases. PubMed ID: 8552593

Generation and characterization of EphA1 receptor tyrosine kinase reporter knockout mice. PubMed ID: 18802966

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079