Details for: Epha8
Associated with
Other Information
Genular Protein ID: 114387747
Symbol: EPHA8_MOUSE
Name: Ephrin type-A receptor 8
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9053851
Title: The Eek receptor, a member of the Eph family of tyrosine protein kinases, can be activated by three different Eph family ligands.
PubMed ID: 9053851
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 9214628
Title: Aberrant axonal projections in mice lacking EphA8 (Eek) tyrosine protein kinase receptors.
PubMed ID: 9214628
PubMed ID: 10498895
Title: Phosphorylation at Tyr-838 in the kinase domain of EphA8 modulates Fyn binding to the Tyr-615 site by enhancing tyrosine kinase activity.
PubMed ID: 10498895
PubMed ID: 11416136
Title: The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner.
PubMed ID: 11416136
PubMed ID: 12681484
Title: The p110 gamma PI-3 kinase is required for EphA8-stimulated cell migration.
PubMed ID: 12681484
PubMed ID: 15782114
Title: The EphA8 receptor induces sustained MAP kinase activation to promote neurite outgrowth in neuronal cells.
PubMed ID: 15782114
PubMed ID: 17875921
Title: Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function.
PubMed ID: 17875921
DOI: 10.1128/mcb.00794-07
PubMed ID: 20100865
Title: The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors.
PubMed ID: 20100865
DOI: 10.1128/mcb.01605-09
PubMed ID: 20496116
Title: EphA8-ephrinA5 signaling and clathrin-mediated endocytosis is regulated by Tiam-1, a Rac-specific guanine nucleotide exchange factor.
PubMed ID: 20496116
Sequence Information:
- Length: 1004
- Mass: 110705
- Checksum: 8530E8002A6FE502
- Sequence:
MAPARARLSP ALWVVTAAAA ATCVSAGRGE VNLLDTSTIH GDWGWLTYPA HGWDSINEVD ESFRPIHTYQ VCNVMSPNQN NWLRTNWVPR DGARRVYAEI KFTLRDCNSI PGVLGTCKET FNLHYLESDR DLGASTQESQ FLKIDTIAAD ESFTGADLGV RRLKLNTEVR GVGPLSKRGF YLAFQDIGAC LAILSLRIYY KKCPAMVRNL AAFSEAVTGA DSSSLVEVRG QCVRHSEERD TPKMYCSAEG EWLVPIGKCV CSAGYEERRD ACMACELGFY KSAPGDQLCA RCPPHSHSAT PAAQTCRCDL SYYRAALDPP SAACTRPPSA PVNLISSVNG TSVTLEWAPP LDPGGRSDIT YNAVCRRCPW ALSHCEACGS GTRFVPQQTS LAQASLLVAN LLAHMNYSFW IEAVNGVSNL SPEPRSAAVV NITTNQAAPS QVVVIRQERA GQTSVSLLWQ EPEQPNGIIL EYEIKYYEKD KEMQSYSTLK AVTTRATVSG LKPGTRYVFQ VRARTSAGCG RFSQAMEVET GKPRPRYDTR TIVWICLTLI TGLVVLLLLL ICKKRHCGYS KAFQDSDEEK MHYQNGQAPP PVFLPLNHPP GKFPETQFSA EPHTYEEPGR AGRSFTREIE ASRIHIEKII GSGESGEVCY GRLQVPGQRD VPVAIKALKA GYTERQRQDF LSEAAIMGQF DHPNIIRLEG VVTRGRLAMI VTEYMENGSL DAFLRTHDGQ FTIVQLVGML RGVGAGMRYL SDLGYIHRDL AARNVLVDGR LVCKVSDFGL SRALEDDPEA AYTTAGGKIP IRWTAPEAIA FRTFSSASDV WSFGVVMWEV LAYGERPYWN MTNQDVISSV EEGYRLPAPM GCPRALHQLM LDCWHKDRAQ RPRFAHVVSV LDALVHSPES LRATATVSRC PPPAFARSCF DLRAGGSGNG DLTVGDWLDS IRMGRYRDHF AAGGYSSLGM VLRMNAQDVR ALGITLMGHQ KKILGSIQTM RAQLSSTQGP RRHL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.