Genular: Defining Cellular Identity and Function

Details for: Ephb3

Gene ID: 13845

Symbol: Ephb3

Ensembl ID: ENSMUSG00000005958

Description: Eph receptor B3

Associated with

Developmental biology
(R-MMU-1266738)
Eph-ephrin mediated repulsion of cells
(R-MMU-3928665)
Eph-ephrin signaling
(R-MMU-2682334)
Ephb-mediated forward signaling
(R-MMU-3928662)
Ephrin signaling
(R-MMU-3928664)
Angiogenesis
(GO:0001525)
Atp binding
(GO:0005524)
Axonal fasciculation
(GO:0007413)
Axon guidance
(GO:0007411)
Axon guidance receptor activity
(GO:0008046)
Cell migration
(GO:0016477)
Cell projection
(GO:0042995)
Central nervous system projection neuron axonogenesis
(GO:0021952)
Corpus callosum development
(GO:0022038)
Dendrite
(GO:0030425)
Dendritic spine development
(GO:0060996)
Dendritic spine morphogenesis
(GO:0060997)
Digestive tract morphogenesis
(GO:0048546)
Ephrin receptor activity
(GO:0005003)
Ephrin receptor signaling pathway
(GO:0048013)
Kinase activity
(GO:0016301)
Membrane
(GO:0016020)
Multicellular organism development
(GO:0007275)
Nervous system development
(GO:0007399)
Nucleotide binding
(GO:0000166)
Phosphorylation
(GO:0016310)
Plasma membrane
(GO:0005886)
Positive regulation of synapse assembly
(GO:0051965)
Protein autophosphorylation
(GO:0046777)
Protein kinase activity
(GO:0004672)
Protein phosphorylation
(GO:0006468)
Protein tyrosine kinase activity
(GO:0004713)
Regulation of axonogenesis
(GO:0050770)
Regulation of cell-cell adhesion
(GO:0022407)
Regulation of gtpase activity
(GO:0043087)
Retinal ganglion cell axon guidance
(GO:0031290)
Roof of mouth development
(GO:0060021)
Substrate adhesion-dependent cell spreading
(GO:0034446)
Thymus development
(GO:0048538)
Transferase activity
(GO:0016740)
Transmembrane-ephrin receptor activity
(GO:0005005)
Transmembrane receptor protein tyrosine kinase activity
(GO:0004714)
Transmembrane receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Urogenital system development
(GO:0001655)

Other Information

Proteins

Ephrin type-B receptor 3

Genular Protein ID: 230168627

Symbol: EPHB3_MOUSE

Name: Ephrin type-B receptor 3

UniProtKB Accession Codes:

P54754 Q62214 Q91YS9

Database IDs:

Citations:

PubMed ID: 7478528

Title: Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family.

PubMed ID: 7478528

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7947319

Title: Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain.

PubMed ID: 7947319

DOI: 10.1016/0925-4773(94)90091-4

PubMed ID: 8947026

Title: Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation.

PubMed ID: 8947026

DOI: 10.1002/j.1460-2075.1996.tb00992.x

PubMed ID: 9990854

Title: Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis.

PubMed ID: 9990854

DOI: 10.1101/gad.13.3.295

PubMed ID: 10704386

Title: Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons.

PubMed ID: 10704386

DOI: 10.1242/dev.127.7.1397

PubMed ID: 12408869

Title: Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.

PubMed ID: 12408869

DOI: 10.1016/s0092-8674(02)01015-2

PubMed ID: 14691139

Title: Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus.

PubMed ID: 14691139

DOI: 10.1083/jcb.200306033

PubMed ID: 15223334

Title: Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development.

PubMed ID: 15223334

DOI: 10.1016/j.ydbio.2004.03.027

PubMed ID: 19598115

Title: On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network.

PubMed ID: 19598115

DOI: 10.1387/ijdb.082702jg

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27446912

Title: Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis.

PubMed ID: 27446912

DOI: 10.3389/fcell.2016.00058

Sequence Information:

Length: 993
Mass: 109662
Checksum: 07C6EF2AC98AE1B4
Sequence:

MAGARPPPGL LPLLAPLLLP LLLPAGCWAL EETLMDTKWV TSELAWTSHP ESGWEEVSGY 
DEAMNPIRTY QVCNVRESSQ NNWLRTGFIW RREVQRVYVE LKFTVRDCNS IPNIPGSCKE 
TFNLFYYEAD SDVASASSPF WMENPYVKVD TIAPDESFSR LDAGRVNTKV RSFGPLSKAG 
FYLAFQDQGA CMSLISVRAF YKKCASTTAG FALFPETLTG AEPTSLVIAP GTCIANAVEV 
SVPLKLYCNG DGEWMVPVGA CTCATGHEPA AKESQCRACP PGSYKAKQGE GPCLPCPPNS 
RTTSPAASIC TCHNNFYRAD SDSADSACTT VPSPPRGVIS NVNETSLILE WSEPRDLGGR 
DDLLYNVICK KCRGSSGAGG PATCSRCDDN VEFVPRQLGL TERRVHISHL LAHTRYTFEV 
QAVNGVSGKS PLPPRYAAVN ITTNQAAPSE VPTLHLHSSS GSSLTLSWAP PERPNGVILD 
YEMKYFEKSK GIASTVTSQK NSVQLDGLQP DARYVVQVRA RTVAGYGQYS HPAEFETTSE 
RGSGAQQLQE QLPLIVGSTV AGFVFMVVVV VIALVCLRKQ RHGPDAEYTE KLQQYIAPGM 
KVYIDPFTYE DPNEAVREFA KEIDVSCVKI EEVIGAGEFG EVCRGRLKLP GRREVFVAIK 
TLKVGYTERQ RRDFLSEASI MGQFDHPNII RLEGVVTKSR PVMILTEFME NCALDSFLRL 
NDGQFTVIQL VGMLRGIAAG MKYLSEMNYV HRDLAARNIL VNSNLVCKVS DFGLSRFLED 
DPSDPTYTSS LGGKIPIRWT APEAIAYRKF TSASDVWSYG IVMWEVMSYG ERPYWDMSNQ 
DVINAVEQDY RLPPPMDCPT ALHQLMLDCW VRDRNLRPKF SQIVNTLDKL IRNAASLKVT 
ASAPSGMSQP LLDRTVPDYT TFTTVGDWLD AIKMGRYKES FVGAGFASFD LVAQMTAEDL 
LRIGVTLAGH QKKILCSIQD MRLQMNQTLP VQV

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ephb3

Associated with

Other Information

Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family. PubMed ID: 7478528

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain. PubMed ID: 7947319

Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. PubMed ID: 8947026

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. PubMed ID: 9990854

Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons. PubMed ID: 10704386

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. PubMed ID: 12408869

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. PubMed ID: 14691139

Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. PubMed ID: 15223334

On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network. PubMed ID: 19598115

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Gene expression profiling of muscle stem cells identifies novel regulators of postnatal myogenesis. PubMed ID: 27446912