Details for: CREB1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: germ cell (CL0000586)
Fold Change: 2.24
Marker Score: 3908.5 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.89
Marker Score: 7898 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.66
Marker Score: 37197 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.65
Marker Score: 1239 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.64
Marker Score: 8621 - Cell Name: neuron (CL0000540)
Fold Change: 1.62
Marker Score: 6599 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.58
Marker Score: 97325 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.55
Marker Score: 59033 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.51
Marker Score: 1825 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.51
Marker Score: 6303.5 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.51
Marker Score: 14360 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 1.51
Marker Score: 55557 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.49
Marker Score: 2094.5 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.49
Marker Score: 22249 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.48
Marker Score: 734 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.48
Marker Score: 29369 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.48
Marker Score: 1698 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.47
Marker Score: 877 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.47
Marker Score: 12588 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.45
Marker Score: 14953 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.44
Marker Score: 4832 - Cell Name: stellate neuron (CL0000122)
Fold Change: 1.44
Marker Score: 7724 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.44
Marker Score: 602 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.44
Marker Score: 837 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 1.43
Marker Score: 5934 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 1.43
Marker Score: 30531 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.43
Marker Score: 3135 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.41
Marker Score: 1521 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.4
Marker Score: 5415 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.39
Marker Score: 10657 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.37
Marker Score: 5729.5 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.37
Marker Score: 12845 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.35
Marker Score: 1164 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.34
Marker Score: 1479.5 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.32
Marker Score: 2033 - Cell Name: basal cell (CL0000646)
Fold Change: 1.31
Marker Score: 1689 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.3
Marker Score: 43774 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.29
Marker Score: 3078 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 1.27
Marker Score: 1531.5 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.27
Marker Score: 617 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.27
Marker Score: 371 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.27
Marker Score: 791 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.27
Marker Score: 1576 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.25
Marker Score: 19535 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.24
Marker Score: 2385 - Cell Name: podocyte (CL0000653)
Fold Change: 1.23
Marker Score: 454 - Cell Name: fat cell (CL0000136)
Fold Change: 1.23
Marker Score: 686 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 1.23
Marker Score: 1126 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.19
Marker Score: 669 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.19
Marker Score: 285 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.19
Marker Score: 1253 - Cell Name: pro-B cell (CL0000826)
Fold Change: 1.19
Marker Score: 1144 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.18
Marker Score: 478 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.18
Marker Score: 3207 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.16
Marker Score: 1306 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.16
Marker Score: 1107 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.16
Marker Score: 333.5 - Cell Name: granule cell (CL0000120)
Fold Change: 1.16
Marker Score: 8714 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.15
Marker Score: 998 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.15
Marker Score: 1157 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.14
Marker Score: 564 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.14
Marker Score: 463 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.13
Marker Score: 20117 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.12
Marker Score: 1389 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 1.12
Marker Score: 257 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 1.12
Marker Score: 330 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 1.12
Marker Score: 1322 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.12
Marker Score: 306 - Cell Name: mature microglial cell (CL0002629)
Fold Change: 1.12
Marker Score: 404.5 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.11
Marker Score: 11283 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.11
Marker Score: 648 - Cell Name: ependymal cell (CL0000065)
Fold Change: 1.1
Marker Score: 385 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.1
Marker Score: 2537 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.1
Marker Score: 5102 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.1
Marker Score: 1173 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.09
Marker Score: 1923 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.08
Marker Score: 1531 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.07
Marker Score: 344 - Cell Name: Schwann cell (CL0002573)
Fold Change: 1.07
Marker Score: 370 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.06
Marker Score: 396 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.06
Marker Score: 636 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.06
Marker Score: 3135 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.06
Marker Score: 936 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.05
Marker Score: 2203 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.05
Marker Score: 331 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.05
Marker Score: 332 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.05
Marker Score: 2848 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.04
Marker Score: 227 - Cell Name: mononuclear phagocyte (CL0000113)
Fold Change: 1.03
Marker Score: 1039 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.03
Marker Score: 1755 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.03
Marker Score: 1461 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.03
Marker Score: 534 - Cell Name: oogonial cell (CL0000024)
Fold Change: 1.03
Marker Score: 1482 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.02
Marker Score: 319 - Cell Name: CD4-positive helper T cell (CL0000492)
Fold Change: 1.02
Marker Score: 1107 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.02
Marker Score: 346 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.01
Marker Score: 1074.5 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.01
Marker Score: 556 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.01
Marker Score: 2374 - Cell Name: neural cell (CL0002319)
Fold Change: 1
Marker Score: 484
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Other Information
Genular Protein ID: 3729862135
Symbol: CREB1_HUMAN
Name: Cyclic AMP-responsive element-binding protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2142528
Title: Two distinct forms of active transcription factor CREB (cAMP response element binding protein).
PubMed ID: 2142528
PubMed ID: 2196176
Title: Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1: all contain a leucine zipper structure and basic amino acid domain.
PubMed ID: 2196176
PubMed ID: 1966745
Title: Diversification of cyclic AMP-responsive enhancer binding proteins-generated by alternative exon splicing.
PubMed ID: 1966745
PubMed ID: 2974179
Title: Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA.
PubMed ID: 2974179
PubMed ID: 1831258
Title: Nucleotide and derived amino-acid sequences of the CRE-binding proteins from rat C6 glioma and HeLa cells.
PubMed ID: 1831258
PubMed ID: 15579595
Title: Cloning and expression of a novel CREB mRNA splice variant in human testis.
PubMed ID: 15579595
DOI: 10.1530/rep.1.00036
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8381074
Title: The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription.
PubMed ID: 8381074
PubMed ID: 1827531
Title: HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions.
PubMed ID: 1827531
PubMed ID: 1386673
Title: Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.
PubMed ID: 1386673
PubMed ID: 8065343
Title: Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.
PubMed ID: 8065343
PubMed ID: 7608156
Title: Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133.
PubMed ID: 7608156
PubMed ID: 9829964
Title: CREB is a regulatory target for the protein kinase Akt/PKB.
PubMed ID: 9829964
PubMed ID: 9770464
Title: Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene.
PubMed ID: 9770464
PubMed ID: 14536081
Title: TORCs: transducers of regulated CREB activity.
PubMed ID: 14536081
PubMed ID: 12552083
Title: Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia.
PubMed ID: 12552083
PubMed ID: 14506290
Title: Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.
PubMed ID: 14506290
PubMed ID: 15454081
Title: The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
PubMed ID: 15454081
PubMed ID: 15964553
Title: TSSK5, a novel member of the testis-specific serine/threonine kinase family, phosphorylates CREB at Ser-133, and stimulates the CRE/CREB responsive pathway.
PubMed ID: 15964553
PubMed ID: 16325578
Title: A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription.
PubMed ID: 16325578
PubMed ID: 15733869
Title: Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.
PubMed ID: 15733869
PubMed ID: 16908542
Title: PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth.
PubMed ID: 16908542
DOI: 10.1128/mcb.00585-06
PubMed ID: 17724745
Title: EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.
PubMed ID: 17724745
DOI: 10.1002/gcc.20491
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20573984
Title: Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.
PubMed ID: 20573984
PubMed ID: 21172805
Title: TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex.
PubMed ID: 21172805
DOI: 10.1242/jcs.068759
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22267179
Title: A p.D116G mutation in CREB1 leads to novel multiple malformation syndrome resembling CrebA knockout mouse.
PubMed ID: 22267179
DOI: 10.1002/humu.22027
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 23651431
Title: Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core.
PubMed ID: 23651431
DOI: 10.1021/cb4002188
Sequence Information:
- Length: 327
- Mass: 35136
- Checksum: F5BA8200EE5184B7
- Sequence:
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQIST IAESEDSQES VDSVTDSQKR REILSRRPSY RKILNDLSSD APGVPRIEEE KSEEETSAPA ITTVTVPTPI YQTSSGQYIA ITQGGAIQLA NNGTDGVQGL QTLTMTNAAA TQPGTTILQY AQTTDGQQIL VPSNQVVVQA ASGDVQTYQI RTAPTSTIAP GVVMASSPAL PTQPAEEAAR KREVRLMKNR EAARECRRKK KEYVKCLENR VAVLENQNKT LIEELKALKD LYCHKSD
Genular Protein ID: 2984114285
Symbol: Q5U0J5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
Sequence Information:
- Length: 341
- Mass: 36688
- Checksum: D5E989AE40BF69AF
- Sequence:
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR IEEEKSEEET SAPAITTVTV PTPIYQTSSG QYIAITQGGA IQLANNGTDG VQGLQTLTMT NAAATQPGTT ILQYAQTTDG QQILVPSNQV VVQAASGDVQ TYQIRTAPTS TIAPGVVMAS SPALPTQPAE EAARKREVRL MKNREAAREC RRKKKEYVKC LENRVAVLEN QNKTLIEELK ALKDLYCHKS D
Genular Protein ID: 4055913484
Symbol: B7Z5C6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 234
- Mass: 24653
- Checksum: 1ED57E58A3FBC079
- Sequence:
MTMESGAENQ QSGDAAVTEA ENQQMTVQAL PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQIST IAESEDSQES VDSVTDSQKR REILSRRPSY RKILNDLSSD APGVPRIEEE KSEEETSAPA ITTVTVPTPI YQTSSGQYIA ITQGGAIQLA NNGTDGVQGL QTLTMTNAAA TQPGTTILQY AQTTDGQQIL VPSNQVVVQG TQKL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.