Details for: Ephx2

Gene ID: 13850

Symbol: Ephx2

Ensembl ID: ENSMUSG00000022040

Description: epoxide hydrolase 2, cytoplasmic

Associated with

Other Information

Genular Protein ID: 1564585823

Symbol: HYES_MOUSE

Name: Cytosolic epoxide hydrolase 2

UniProtKB Accession Codes:

P34914 Q8CGV0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CDD 1 CTD 1 ChEBI 89 ChEMBL 1 ChiTaRS 1 DNASU 1 EC 2 EMBL 4 ESTHER 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 2 GeneTree 1 Genevisible 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MEROPS 1 MGI 2 MINT 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 4 PIR 1 PRINTS 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 2 Rhea 48 SFLD 2 SMR 1 STRING 1 SUPFAM 2 SWISS-2DPAGE 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 2 UniProtKB 2 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 8349642

Title: Molecular cloning and expression of murine liver soluble epoxide hydrolase.

PubMed ID: 8349642

DOI: 10.1016/s0021-9258(19)85378-4

PubMed ID: 8750907

Title: Tissue specific basal expression of soluble murine epoxide hydrolase and effects of clofibrate on the mRNA levels in extrahepatic tissues and liver.

PubMed ID: 8750907

DOI: 10.1007/s002040050250

PubMed ID: 15601917

Title: Identification and characterization of an ovary-selective isoform of epoxide hydrolase.

PubMed ID: 15601917

DOI: 10.1095/biolreprod.104.035899

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7840649

Title: Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis.

PubMed ID: 7840649

DOI: 10.1006/abbi.1995.1059

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21217101

Title: Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase.

PubMed ID: 21217101

DOI: 10.1194/jlr.m009639

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 10485878

Title: Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.

PubMed ID: 10485878

DOI: 10.1073/pnas.96.19.10637

PubMed ID: 10747889

Title: Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation.

PubMed ID: 10747889

DOI: 10.1074/jbc.m000278200

Sequence Information:

  • Length: 554
  • Mass: 62515
  • Checksum: 2F3A3F7DACE47C93
  • Sequence:
    • MALRVAAFDL DGVLALPSIA GAFRRSEEAL ALPRDFLLGA YQTEFPEGPT EQLMKGKITF 
SQWVPLMDES YRKSSKACGA NLPENFSISQ IFSQAMAARS INRPMLQAAI ALKKKGFTTC 
IVTNNWLDDG DKRDSLAQMM CELSQHFDFL IESCQVGMIK PEPQIYNFLL DTLKAKPNEV 
VFLDDFGSNL KPARDMGMVT ILVHNTASAL RELEKVTGTQ FPEAPLPVPC NPNDVSHGYV 
TVKPGIRLHF VEMGSGPALC LCHGFPESWF SWRYQIPALA QAGFRVLAID MKGYGDSSSP 
PEIEEYAMEL LCKEMVTFLD KLGIPQAVFI GHDWAGVMVW NMALFYPERV RAVASLNTPF 
MPPDPDVSPM KVIRSIPVFN YQLYFQEPGV AEAELEKNMS RTFKSFFRAS DETGFIAVHK 
ATEIGGILVN TPEDPNLSKI TTEEEIEFYI QQFKKTGFRG PLNWYRNTER NWKWSCKGLG 
RKILVPALMV TAEKDIVLRP EMSKNMEKWI PFLKRGHIED CGHWTQIEKP TEVNQILIKW 
LQTEVQNPSV TSKI

Genular Protein ID: 3234138095

Symbol: Q3UQ71_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3UQ71

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ESTHER 1 GO 1 Gene3D 2 InterPro 8 KEGG 1 MGI 2 NCBI Taxonomy 1 NCBIfam 2 OrthoDB 1 PANTHER 2 PRINTS 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SFLD 2 SMR 1 SUPFAM 2 SwissPalm 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 554
  • Mass: 62543
  • Checksum: C248AF829EB9DFD1
  • Sequence:
    • MALRVAAFDL DGVLALPSIA GAFRRSEEAL ALPRDFLLGA YQTEFPEGPT EQLMKGKITF 
SQWVPLMDES YRKSSKACGA NLPENFSISQ IFSQAMAARS INRPMLQAAI ALKKKGFTTC 
IVTNNWLDDG DKRDSLAQMM CELSQHFDFL IESCQVGMIK PEPRIYNFLL DTLKAKPNEV 
VFLDDFGSNL KPARDMGMVT ILVHNTASAL RELEKVTGTQ FPEAPLPVPC NPNDVSHGYV 
TVKPGIRLHF VEMGSGPALC LCHGFPESWF SWRYQIPALA QAGFRVLAID MKGYGDSSSP 
PEIEEYAMEL LCKEMVTFLD KLGIPQAVFI GHDWAGVMVW NMALFYPERV RAVASLNTPF 
MPPDPDVSPM KVIRSIPVFN YQLYFQEPGV AEAELEKNMS RTFKSFFRAS DETGFIAVHK 
ATEIGGILVN TPEDPNLSKI TTEEEIEFYI QQFKKTGFRG PLNWYRNTER NWKWSCKGLG 
RKILVPALMV TAEKDIVLRP EMSKNMEKWI PFLKRGHIED CGHWTQIEKP TEVNQILIKW 
LQTEVQNPSV TSKI

Genular Protein ID: 807189475

Symbol: A8JYK8_MOUSE

Name: N/A

UniProtKB Accession Codes:

A8JYK8

Database IDs:

AGR 1 ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 ESTHER 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 2 GeneTree 1 InterPro 6 MGI 2 MaxQB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 17900570

Title: A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2.

PubMed ID: 17900570

DOI: 10.1016/j.febslet.2007.09.016

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

  • Length: 488
  • Mass: 55281
  • Checksum: BAA330F8BCEFE5AF
  • Sequence:
    • MDESYRKSSK ACGANLPENF SISQIFSQAM AARSINRPML QAAIALKKKG FTTCIVTNNW 
LDDGDKRDSL AQMMCELSQH FDFLIESCQV GMIKPEPQIY NFLLDTLKAK PNEVVFLDDF 
GSNLKPARDM GMVTILVHNT ASALRELEKV TGTQFPEAPL PVPCNPNDVS HGYVTVKPGI 
RLHFVEMGSG PALCLCHGFP ESWFSWRYQI PALAQAGFRV LAIDMKGYGD SSSPPEIEEY 
AMELLCKEMV TFLDKLGIPQ AVFIGHDWAG VMVWNMALFY PERVRAVASL NTPFMPPDPD 
VSPMKVIRSI PVFNYQLYFQ EPGVAEAELE KNMSRTFKSF FRASDETGFI AVHKATEIGG 
ILVNTPEDPN LSKITTEEEI EFYIQQFKKT GFRGPLNWYR NTERNWKWSC KGLGRKILVP 
ALMVTAEKDI VLRPEMSKNM EKWIPFLKRG HIEDCGHWTQ IEKPTEVNQI LIKWLQTEVQ 
NPSVTSKI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.