Genular: Defining Cellular Identity and Function

Details for: Epn1

Gene ID: 13854

Symbol: Epn1

Ensembl ID: ENSMUSG00000035203

Description: epsin 1

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-MMU-8856825)
Clathrin-mediated endocytosis
(R-MMU-8856828)
Egfr downregulation
(R-MMU-182971)
Membrane trafficking
(R-MMU-199991)
Signaling by egfr
(R-MMU-177929)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Vesicle-mediated transport
(R-MMU-5653656)
Clathrin-coated pit
(GO:0005905)
Clathrin adaptor activity
(GO:0035615)
Clathrin binding
(GO:0030276)
Clathrin coat assembly
(GO:0048268)
Clathrin vesicle coat
(GO:0030125)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Embryonic organ development
(GO:0048568)
Endocytosis
(GO:0006897)
Endosome
(GO:0005768)
Female pregnancy
(GO:0007565)
In utero embryonic development
(GO:0001701)
Lipid binding
(GO:0008289)
Membrane
(GO:0016020)
Membrane fission
(GO:0090148)
Molecular sequestering activity
(GO:0140313)
Negative regulation of sprouting angiogenesis
(GO:1903671)
Notch signaling pathway
(GO:0007219)
Nucleus
(GO:0005634)
Phospholipid binding
(GO:0005543)
Plasma membrane
(GO:0005886)
Positive regulation of clathrin coat assembly
(GO:1905445)
Postsynapse
(GO:0098794)
Postsynaptic membrane
(GO:0045211)
Presynapse
(GO:0098793)
Presynaptic membrane
(GO:0042734)
Schaffer collateral - ca1 synapse
(GO:0098685)
Transmembrane transporter binding
(GO:0044325)

Other Information

Proteins

Epsin-1

Genular Protein ID: 4256164834

Symbol: EPN1_MOUSE

Name: Epsin-1

UniProtKB Accession Codes:

Q80VP1 O70446 Q6NX78

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9813051

Title: Intersectin, a novel adaptor protein with two eps15 homology and five src homology 3 domains.

PubMed ID: 9813051

DOI: 10.1074/jbc.273.47.31401

PubMed ID: 9920862

Title: The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals.

PubMed ID: 9920862

DOI: 10.1074/jbc.274.6.3257

PubMed ID: 15345747

Title: Phosphoproteomic analysis of the developing mouse brain.

PubMed ID: 15345747

DOI: 10.1074/mcp.m400085-mcp200

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

Sequence Information:

Length: 575
Mass: 60212
Checksum: 70B8011EB3AE5C4C
Sequence:

MSTSSLRRQM KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMI 
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVSQQCKENM YAVQTLKDFQ YVDRDGKDQG 
VNVREKAKQL VALLRDEDRL REERAHALKT KEKLAQTATA SSAAVGSGPP PEAEQAWPQS 
SGEEELQLQL ALAMSKEEAD QPPSCGPEDD VQLQLALSLS REEHDKEERI RRGDDLRLQM 
AIEESKRETG GKEESSLMDL ADVFTTPAPP QASDPWGGPA SVPTAVPVAA AASDPWGGPA 
VPPAADPWGG AAPTPASGDP WRPAAPTGPS VDPWGGTPAP AAGEGPTPDP WGSSDGGAPV 
SGPPSSDPWA PAPAFSDPWG GSPAKPSSNG TAVGGFDTEP DEFSDFDRLR TALPTSGSST 
GELELLAGEV PARSPGAFDM SGVGGSLAES VGSPPPAATP TPTPPTRKTP ESFLGPNAAL 
VDLDSLVSRP GPTPPGSKAS NPFLPSGAPP TGPSVTNPFQ PAPPATLTLN QLRLSPVPPV 
PGAPPTYISP LGGGPGLPPM MPPGPPAPNT NPFLL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Epn1

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Intersectin, a novel adaptor protein with two eps15 homology and five src homology 3 domains. PubMed ID: 9813051

The interaction of epsin and Eps15 with the clathrin adaptor AP-2 is inhibited by mitotic phosphorylation and enhanced by stimulation-dependent dephosphorylation in nerve terminals. PubMed ID: 9920862

Phosphoproteomic analysis of the developing mouse brain. PubMed ID: 15345747

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315