Details for: Epo

Gene ID: 13856

Symbol: Epo

Ensembl ID: ENSMUSG00000029711

Description: erythropoietin

Associated with

  • Erythropoietin activates phosphoinositide-3-kinase (pi3k)
    (R-MMU-9027276)
  • Erythropoietin activates ras
    (R-MMU-9027284)
  • Signaling by erythropoietin
    (R-MMU-9006335)
  • Signal transduction
    (R-MMU-162582)
  • Angiogenesis
    (GO:0001525)
  • Apoptotic process
    (GO:0006915)
  • Cardiac muscle tissue morphogenesis
    (GO:0055008)
  • Cell body
    (GO:0044297)
  • Cell surface
    (GO:0009986)
  • Cellular hyperosmotic response
    (GO:0071474)
  • Cytokine activity
    (GO:0005125)
  • Embryo implantation
    (GO:0007566)
  • Erythrocyte differentiation
    (GO:0030218)
  • Erythrocyte maturation
    (GO:0043249)
  • Erythropoietin-mediated signaling pathway
    (GO:0038162)
  • Erythropoietin receptor binding
    (GO:0005128)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Heart morphogenesis
    (GO:0003007)
  • Hemoglobin biosynthetic process
    (GO:0042541)
  • Hormone activity
    (GO:0005179)
  • Myeloid cell apoptotic process
    (GO:0033028)
  • Negative regulation of apoptotic process
    (GO:0043066)
  • Negative regulation of calcium ion transport into cytosol
    (GO:0010523)
  • Negative regulation of cation channel activity
    (GO:2001258)
  • Negative regulation of erythrocyte apoptotic process
    (GO:1902251)
  • Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
    (GO:1902219)
  • Negative regulation of myeloid cell apoptotic process
    (GO:0033033)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Peptidyl-serine phosphorylation
    (GO:0018105)
  • Positive regulation of activated t cell proliferation
    (GO:0042104)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of neuron projection development
    (GO:0010976)
  • Positive regulation of protein kinase activity
    (GO:0045860)
  • Positive regulation of ras protein signal transduction
    (GO:0046579)
  • Positive regulation of tyrosine phosphorylation of stat protein
    (GO:0042531)
  • Protein kinase activator activity
    (GO:0030295)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to hypoxia
    (GO:0001666)
  • Vasculogenesis involved in coronary vascular morphogenesis
    (GO:0060979)
  • Ventricular cardiac muscle tissue morphogenesis
    (GO:0055010)
  • Visceral serous pericardium development
    (GO:0061032)

Other Information

Genular Protein ID: 1914252063

Symbol: EPO_MOUSE

Name: Erythropoietin

UniProtKB Accession Codes:

P07321

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 51 Gene3D 1 GeneTree 1 GlyCosmos 1 GlyGen 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 1 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 3773894

Title: Murine erythropoietin gene: cloning, expression, and human gene homology.

PubMed ID: 3773894

DOI: 10.1128/mcb.6.3.849-858.1986

PubMed ID: 3022133

Title: Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene.

PubMed ID: 3022133

DOI: 10.1128/mcb.6.3.842-848.1986

PubMed ID: 11239002

Title: Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.

PubMed ID: 11239002

DOI: 10.1093/nar/29.6.1352

PubMed ID: 9365246

Title: Abnormal erythropoietin (Epo) gene expression in the murine erythroleukemia IW32 cells results from a rearrangement between the G-protein beta2 subunit gene and the Epo gene.

PubMed ID: 9365246

DOI: 10.1038/sj.onc.1201364

Sequence Information:

  • Length: 192
  • Mass: 21365
  • Checksum: 65F94E214E0DEF2E
  • Sequence:
    • MGVPERPTLL LLLSLLLIPL GLPVLCAPPR LICDSRVLER YILEAKEAEN VTMGCAEGPR 
LSENITVPDT KVNFYAWKRM EVEEQAIEVW QGLSLLSEAI LQAQALLANS SQPPETLQLH 
IDKAISGLRS LTSLLRVLGA QKELMSPPDT TPPAPLRTLT VDTFCKLFRV YANFLRGKLK 
LYTGEVCRRG DR

Genular Protein ID: 149855420

Symbol: B7ZMY9_MOUSE

Name: N/A

UniProtKB Accession Codes:

B7ZMY9

Database IDs:

AGR 1 ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HOGENOM 1 InterPro 4 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 191
  • Mass: 21237
  • Checksum: E3530A426E25352A
  • Sequence:
    • MGVPERPTLL LLLSLLLIPL GLPVLCAPPR LICDSRVLER YILEAKEAEN VTMGCAEGPR 
LSENITVPDT KVNFYAWKRM EVEEQAIEVW QGLSLLSEAI LQAQALLANS SQPPETLQLH 
IDKAISGLRS LTSLLRVLGA QELMSPPDTT PPAPLRTLTV DTFCKLFRVY ANFLRGKLKL 
YTGEVCRRGD R

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.