Genular: Defining Cellular Identity and Function

Details for: Epx

Gene ID: 13861

Symbol: Epx

Ensembl ID: ENSMUSG00000052234

Description: eosinophil peroxidase

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Neutrophil degranulation
(R-MMU-6798695)
Defense response to bacterium
(GO:0042742)
Defense response to nematode
(GO:0002215)
Eosinophil migration
(GO:0072677)
Extracellular space
(GO:0005615)
Heme binding
(GO:0020037)
Hydrogen peroxide catabolic process
(GO:0042744)
Interleukin-4 production
(GO:0032633)
Interleukin-5 production
(GO:0032634)
Interleukin-10 production
(GO:0032613)
Lactoperoxidase activity
(GO:0140825)
Macrophage cytokine production
(GO:0010934)
Metal ion binding
(GO:0046872)
Negative regulation of interleukin-5 production
(GO:0032714)
Negative regulation of interleukin-10 production
(GO:0032693)
Negative regulation of macrophage cytokine production
(GO:0010936)
Oxidoreductase activity
(GO:0016491)
Peroxidase activity
(GO:0004601)
Positive regulation of interleukin-4 production
(GO:0032753)
Response to oxidative stress
(GO:0006979)

Other Information

Proteins

Eosinophil peroxidase
Q3V1J3_MOUSE

Genular Protein ID: 4125202551

Symbol: PERE_MOUSE

Name: Eosinophil peroxidase

UniProtKB Accession Codes:

P49290 Q5SW51 Q61798

Database IDs:

Citations:

PubMed ID: 8773591

Title: Cloning of the murine eosinophil peroxidase gene (mEPO): characterization of a conserved subgroup of mammalian hematopoietic peroxidases.

PubMed ID: 8773591

DOI: 10.1002/jlb.60.2.285

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 18694936

Title: Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase.

PubMed ID: 18694936

DOI: 10.1074/jbc.m801196200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 716
Mass: 81380
Checksum: 9D1D1A88E6E259A1
Sequence:

MMQQLLALVG ALATLILTQH AEGTAPASPS PVEISVLRDC IAEAKLLVDT AYNHTQKSIM 
QRLRSGSASP MDLLAYFKQP VAATRRVVQA ADYMHVALGL LEERLQPRGS RPFNATDVLT 
EPQLRLLSQA SGCALQDQAE RCSNKYRTIT GRCNNKKHPW LGASNQALAR WLPAEYEDHR 
SLPFGWTPGK RRNGFLLPLV RDVSNQIVRF PSKKLTSDRG RALMFMQWGQ FIDHDLDFSP 
ESPARVAFSM GVDCEKTCAQ LPPCFPIKIP RNDPRIKNQR DCIPFFRSAP ACPQNRNKVR 
NQINALTSFV DASMVYGSEV TLALRLRNRT NFLGLLATNQ RFQDNGRALL PFDNLHEDPC 
LLTNRSARIP CFLAGDTRSS ETPKLTALHT LFVREHNRLA AELRRLNPHW SGDKLYNEAR 
KIVGAMVQII TYRDFLPLVL GRARIRRTLG PYRGYCSNVD PRVANVFTLA FRFGHTMLQP 
FMFRLDSQYR ASAPNSHVPL SSVFFASWRI IHEGGIDPIL RGLMATPAKL NRQDSMLVDE 
LRDKLFQQVR RIGLDLAALN MQRSRDHGLP GYNAWRRFCG LSQPRNLAQL SRVLKNQDLA 
RKFLRLYKTP DNIDIWVGAI AEPLLPGARV GPLLACLFEN QFRRARDGDR FWWQKWGVFT 
KRQRKALRRI SLSRIVCDNT GITTVSRDIF RANIYPQGFV SCSRIPKLNL SAWRGK

Genular Protein ID: 4047891538

Symbol: Q3V1J3_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3V1J3

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 403
Mass: 46387
Checksum: 76E832B859728A55
Sequence:

MVYGSEVTLA LRLRNRTNFL GLLATNQRFQ DNGRALLPFD NLHEDPCLLT NRSARIPCFL 
AGDTRSSETP KLTALHTLFV REHNRLAAEL RRLNPHWSGD KLYNEARKIV GAMVQIITYR 
DFLPLVLGRA RIRRTLGPYR GYCSNVDPRV ANVFTLAFRF GHTMLQPFMF RLDSQYRASA 
PNSHVPLSSV FFASWRIIHE GGIDPILRGL MATPAKLNRQ DSMLVDELRD KLFQQVRRIG 
LDLAALNMQR SRDHGLPGYN AWRRFCGLSQ PRNLAQLSRV LKNQDLARKF LRLYKTPDNI 
DIWVGAIAEP LLPGARVGPL LACLFENQFR RARDGDRFWW QKWGVFTKRQ RKALRRISLS 
RIVCDNTGIT TVSRDIFRAN IYPQGFVSCS RIPKLNLSAW RGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Epx

Associated with

Other Information

Cloning of the murine eosinophil peroxidase gene (mEPO): characterization of a conserved subgroup of mammalian hematopoietic peroxidases. PubMed ID: 8773591

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. PubMed ID: 18694936

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073