Genular: Defining Cellular Identity and Function

Details for: Nr2f6

Gene ID: 13864

Symbol: Nr2f6

Ensembl ID: ENSMUSG00000002393

Description: nuclear receptor subfamily 2, group F, member 6

Associated with

Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Nuclear receptor transcription pathway
(R-MMU-383280)
Rna polymerase ii transcription
(R-MMU-73857)
Anatomical structure development
(GO:0048856)
Cell differentiation
(GO:0030154)
Detection of temperature stimulus involved in sensory perception of pain
(GO:0050965)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Metal ion binding
(GO:0046872)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Neuron development
(GO:0048666)
Nuclear receptor activity
(GO:0004879)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Nuclear receptor subfamily 2 group F member 6

Genular Protein ID: 3519826090

Symbol: NR2F6_MOUSE

Name: Nuclear receptor subfamily 2 group F member 6

UniProtKB Accession Codes:

P43136 Q61504 Q922G8

Database IDs:

Citations:

PubMed ID: 7947324

Title: Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.

PubMed ID: 7947324

DOI: 10.1016/0925-4773(94)90098-1

PubMed ID: 8194772

Title: The sequence of a murine cDNA encoding Ear-2, a nuclear orphan receptor.

PubMed ID: 8194772

DOI: 10.1016/0378-1119(94)90283-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10318855

Title: Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2.

PubMed ID: 10318855

DOI: 10.1074/jbc.274.20.14331

PubMed ID: 11382775

Title: Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.

PubMed ID: 11382775

DOI: 10.1074/jbc.m103577200

PubMed ID: 12690040

Title: Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription.

PubMed ID: 12690040

DOI: 10.1161/01.res.0000071355.82009.43

PubMed ID: 15741322

Title: Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception.

PubMed ID: 15741322

DOI: 10.1101/gad.317905

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18701084

Title: The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

PubMed ID: 18701084

DOI: 10.1016/j.immuni.2008.06.008

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 390
Mass: 41968
Checksum: 4C30B25C6CAE5338
Sequence:

MAMVTGGWGD PGGDTNGVDK AGGSYPRATE DDSASPPGAT SDAEPGDEER PGLQVDCVVC 
GDKSSGKHYG VFTCEGCKSF FKRSIRRNLS YTCRSNRDCQ IDQHHRNQCQ YCRLKKCFRV 
GMRKEAVQRG RIPHALPGPA ACSPPGATGV EPFTGPPVSE LIAQLLRAEP YPAAGRFGGG 
GAVLGIDNVC ELAARLLFST VEWARHAPFF PELPAADQVA LLRLSWSELF VLNAAQAALP 
LHTAPLLAAA GLHAAPMAAE RAVAFMDQVR AFQEQVDKLG RLQVDAAEYG CLKAIALFTP 
DACGLSDPAH VESLQEKAQV ALTEYVRAQY PSQPQRFGRL LLRLPALRAV PASLISQLFF 
MRLVGKTPIE TLIRDMLLSG STFNWPYGSG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nr2f6

Associated with

Other Information

Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors. PubMed ID: 7947324

The sequence of a murine cDNA encoding Ear-2, a nuclear orphan receptor. PubMed ID: 8194772

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2. PubMed ID: 10318855

Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter. PubMed ID: 11382775

Identification of a nuclear orphan receptor (Ear2) as a negative regulator of renin gene transcription. PubMed ID: 12690040

Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception. PubMed ID: 15741322

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity. PubMed ID: 18701084

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079