Details for: Erbb4
Associated with
Other Information
Genular Protein ID: 4103735285
Symbol: ERBB4_MOUSE
Name: Receptor tyrosine-protein kinase erbB-4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19468303
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
PubMed ID: 19468303
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 9334263
Title: A novel juxtamembrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester.
PubMed ID: 9334263
PubMed ID: 7589796
Title: Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle.
PubMed ID: 7589796
PubMed ID: 7477376
Title: Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor.
PubMed ID: 7477376
DOI: 10.1038/378390a0
PubMed ID: 10508857
Title: ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation.
PubMed ID: 10508857
DOI: 10.1083/jcb.147.1.77
PubMed ID: 10353604
Title: Characterization of a naturally occurring ErbB4 isoform that does not bind or activate phosphatidyl inositol 3-kinase.
PubMed ID: 10353604
PubMed ID: 10655590
Title: Defects in pathfinding by cranial neural crest cells in mice lacking the neuregulin receptor ErbB4.
PubMed ID: 10655590
DOI: 10.1038/35000058
PubMed ID: 12954715
Title: Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.
PubMed ID: 12954715
DOI: 10.1242/dev.00715
PubMed ID: 12824469
Title: Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality.
PubMed ID: 12824469
PubMed ID: 15543145
Title: Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain.
PubMed ID: 15543145
DOI: 10.1038/nn1345
PubMed ID: 15863494
Title: ERBB4/HER4 potentiates STAT5A transcriptional activity by regulating novel STAT5A serine phosphorylation events.
PubMed ID: 15863494
PubMed ID: 16815842
Title: ErbB-4 s80 intracellular domain abrogates ETO2-dependent transcriptional repression.
PubMed ID: 16815842
PubMed ID: 16837552
Title: The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells.
PubMed ID: 16837552
PubMed ID: 19596786
Title: ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo.
PubMed ID: 19596786
DOI: 10.1128/mcb.01705-08
PubMed ID: 19632177
Title: Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury.
PubMed ID: 19632177
PubMed ID: 14504474
Title: ErbB4 signaling during breast and neural development: novel genetic models reveal unique ErbB4 activities.
PubMed ID: 14504474
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21295966
Title: Neuregulin signaling, cortical circuitry development and schizophrenia.
PubMed ID: 21295966
Sequence Information:
- Length: 1308
- Mass: 146855
- Checksum: 65943278A7E7F2F6
- Sequence:
MKLATGLWVW GSLLMAAGTV QPSASQSVCA GTENKLSSLS DLEQQYRALR KYYENCEVVM GNLEITSIEH NRDLSFLRSI REVTGYVLVA LNQFRYLPLE NLRIIRGTKL YEDRYALAIF LNYRKDGNFG LQELGLKNLT EILNGGVYVD QNKFLCYADT IHWQDIVRNP WPSNMTLVST NGSSGCGRCH KSCTGRCWGP TENHCQTLTR TVCAEQCDGR CYGPYVSDCC HRECAGGCSG PKDTDCFACM NFNDSGACVT QCPQTFVYNP TTFQLEHNFN AKYTYGAFCV KKCPHNFVVD SSSCVRACPS SKMEVEENGI KMCKPCTDIC PKACDGIGTG SLMSAQTVDS SNIDKFINCT KINGNLIFLV TGIHGDPYNA IDAIDPEKLN VFRTVREITG FLNIQSWPPN MTDFSVFSNL VTIGGRVLYS GLSLLILKQQ GITSLQFQSL KEISAGNIYI TDNSNLCYYH TINWTTLFST INQRIVIRDN RRAENCTAEG MVCNHLCSND GCWGPGPDQC LSCRRFSRGK ICIESCNLYD GEFREFENGS ICVECDSQCE KMEDGLLTCH GPGPDNCTKC SHFKDGPNCV EKCPDGLQGA NSFIFKYADQ DRECHPCHPN CTQGCNGPTS HDCIYYPWTG HSTLPQHART PLIAAGVIGG LFILVIMALT FAVYVRRKSI KKKRALRRFL ETELVEPLTP SGTAPNQAQL RILKETELKR VKVLGSGAFG TVYKGIWVPE GETVKIPVAI KILNETTGPK ANVEFMDEAL IMASMDHPHL VRLLGVCLSP TIQLVTQLMP HGCLLDYVHE HKDNIGSQLL LNWCVQIAKG MMYLEERRLV HRDLAARNVL VKSPNHVKIT DFGLARLLEG DEKEYNADGG KMPIKWMALE CIHYRKFTHQ SDVWSYGVTI WELMTFGGKP YDGIPTREIP DLLEKGERLP QPPICTIDVY MVMVKCWMID ADSRPKFKEL AAEFSRMARD PQRYLVIQGD DRMKLPSPND SKFFQNLLDE EDLEDMMDAE EYLVPQAFNI PPPIYTSRTR IDSNRSEIGH SPPPAYTPMS GNQFVYQDGG FATQQGMPMP YRATTSTIPE APVAQGATAE MFDDSCCNGT LRKPVAPHVQ EDSSTQRYSA DPTVFAPERN PRGELDEEGY MTPMHDKPKQ EYLNPVEENP FVSRRKNGDL QALDNPEYHS ASSGPPKAED EYVNEPLYLN TFANALGSAE YMKNSVLSVP EKAKKAFDNP DYWNHSLPPR STLQHPDYLQ EYSTKYFYKQ NGRIRPIVAE NPEYLSEFSL KPGTMLPPPP YRHRNTVV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.