Genular: Defining Cellular Identity and Function

Details for: Ercc1

Gene ID: 13870

Symbol: Ercc1

Ensembl ID: ENSMUSG00000003549

Description: excision repair cross-complementing rodent repair deficiency, complementation group 1

Associated with

Dna double-strand break repair
(R-MMU-5693532)
Dual incision in gg-ner
(R-MMU-5696400)
Dual incision in tc-ner
(R-MMU-6782135)
Fanconi anemia pathway
(R-MMU-6783310)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Hdr through homologous recombination (hrr) or single strand annealing (ssa)
(R-MMU-5693567)
Hdr through single strand annealing (ssa)
(R-MMU-5685938)
Homology directed repair
(R-MMU-5693538)
Nucleotide excision repair
(R-MMU-5696398)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
3' overhang single-stranded dna endodeoxyribonuclease activity
(GO:1990599)
Cell development
(GO:0048468)
Cell population proliferation
(GO:0008283)
Chromosome, telomeric region
(GO:0000781)
Chromosome organization
(GO:0051276)
Damaged dna binding
(GO:0003684)
Determination of adult lifespan
(GO:0008340)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna recombination
(GO:0006310)
Dna repair
(GO:0006281)
Double-strand break repair
(GO:0006302)
Double-strand break repair via nonhomologous end joining
(GO:0006303)
Ercc4-ercc1 complex
(GO:0070522)
Germ cell development
(GO:0007281)
Insulin-like growth factor receptor signaling pathway
(GO:0048009)
Interstrand cross-link repair
(GO:0036297)
Isotype switching
(GO:0045190)
Male gonad development
(GO:0008584)
Mitotic recombination
(GO:0006312)
Multicellular organism growth
(GO:0035264)
Negative regulation of protection from non-homologous end joining at telomere
(GO:1905765)
Negative regulation of telomere maintenance
(GO:0032205)
Nucleoplasm
(GO:0005654)
Nucleotide-excision repair
(GO:0006289)
Nucleotide-excision repair complex
(GO:0000109)
Nucleotide-excision repair factor 1 complex
(GO:0000110)
Nucleus
(GO:0005634)
Oogenesis
(GO:0048477)
Positive regulation of t-circle formation
(GO:1904431)
Positive regulation of transcription initiation by rna polymerase ii
(GO:0060261)
Post-embryonic hemopoiesis
(GO:0035166)
Promoter-specific chromatin binding
(GO:1990841)
Protein binding
(GO:0005515)
Pyrimidine dimer repair by nucleotide-excision repair
(GO:0000720)
Replicative senescence
(GO:0090399)
Response to oxidative stress
(GO:0006979)
Response to x-ray
(GO:0010165)
Single-stranded dna binding
(GO:0003697)
Single-stranded dna endodeoxyribonuclease activity
(GO:0000014)
Spermatogenesis
(GO:0007283)
Syncytium formation
(GO:0006949)
T-circle formation
(GO:0090656)
Telomeric dna-containing double minutes formation
(GO:0061819)
Tfiid-class transcription factor complex binding
(GO:0001094)
Uv-damage excision repair
(GO:0070914)
Uv protection
(GO:0009650)

Other Information

Proteins

DNA excision repair protein ERCC-1
E9PUM0_MOUSE

Genular Protein ID: 1769583632

Symbol: ERCC1_MOUSE

Name: DNA excision repair protein ERCC-1

UniProtKB Accession Codes:

P07903 Q91VP3

Database IDs:

Citations:

PubMed ID: 3290851

Title: Evolution and mutagenesis of the mammalian excision repair gene ERCC-1.

PubMed ID: 3290851

DOI: 10.1093/nar/16.12.5305

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 298
Mass: 32910
Checksum: 264DF6865A3ED847
Sequence:

MDPGKDEESR PQPSGPPTRR KFVIPLEEEE VPCAGVKPLF RSSRNPTIPA TSAHVAPQTY 
AEYAITQPPG GAGATVPTGS EPAAGENPSQ TLKTGAKSNS IIVSPRQRGN PVLKFVRNVP 
WEFGEVIPDY VLGQSTCALF LSLRYHNLHP DYIHERLQSL GKNFALRVLL VQVDVKDPQQ 
ALKELAKMCI LADCTLVLAW SAEEAGRYLE TYKAYEQKPA DLLMEKLEQN FLSRATECLT 
TVKSVNKTDS QTLLATFGSL EQLFTASRED LALCPGLGPQ KARRLFEVLH EPFLKVPR

Genular Protein ID: 1180265486

Symbol: E9PUM0_MOUSE

Name: N/A

UniProtKB Accession Codes:

E9PUM0

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

Length: 245
Mass: 26948
Checksum: 1AA0DD8EED2EE0B2
Sequence:

MDPGKDEESR PQPSGPPTRR KFVIPLEEEE VPCAGVKPLF RSSRNPTIPA TSAHVAPQTY 
AEYAITQPPG GAGATVPTGS EPAAGENPSQ TLKTGAKSNS IIVSPRQRGN PVLKFVRNVP 
WEFGEVIPDY VLGQSTCALF LSLRYHNLHP DYIHERLQSL GKNFALRVLL VQVDVKDPQQ 
ALKELAKMCI LADCTLVLAW SAEEAGRYLE TYKAYEQKPA DLLMEKLEQN FLSRVSLCLL 
SSCTS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ercc1

Associated with

Other Information

Evolution and mutagenesis of the mammalian excision repair gene ERCC-1. PubMed ID: 3290851

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Database document:

PubMed ID: 3290851

PubMed ID: 16141072

PubMed ID: 19468303

PubMed ID: 15489334

PubMed ID: 19468303