Genular: Defining Cellular Identity and Function

Details for: Ercc3

Gene ID: 13872

Symbol: Ercc3

Ensembl ID: ENSMUSG00000024382

Description: excision repair cross-complementing rodent repair deficiency, complementation group 3

Associated with

Dual incision in gg-ner
(R-MMU-5696400)
Dual incision in tc-ner
(R-MMU-6782135)
Formation of incision complex in gg-ner
(R-MMU-5696395)
Formation of rna pol ii elongation complex
(R-MMU-112382)
Formation of tc-ner pre-incision complex
(R-MMU-6781823)
Formation of the early elongation complex
(R-MMU-113418)
Gap-filling dna repair synthesis and ligation in tc-ner
(R-MMU-6782210)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Global genome nucleotide excision repair (gg-ner)
(R-MMU-5696399)
Metabolism of rna
(R-MMU-8953854)
Mrna capping
(R-MMU-72086)
Nucleotide excision repair
(R-MMU-5696398)
Rna pol ii ctd phosphorylation and interaction with ce
(R-MMU-77075)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii promoter escape
(R-MMU-73776)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Rna polymerase ii transcription initiation
(R-MMU-75953)
Rna polymerase ii transcription initiation and promoter clearance
(R-MMU-76042)
Rna polymerase ii transcription pre-initiation and promoter opening
(R-MMU-73779)
Rna polymerase i promoter clearance
(R-MMU-73854)
Rna polymerase i promoter escape
(R-MMU-73772)
Rna polymerase i transcription
(R-MMU-73864)
Rna polymerase i transcription initiation
(R-MMU-73762)
Rna polymerase i transcription termination
(R-MMU-73863)
Tp53 regulates transcription of dna repair genes
(R-MMU-6796648)
Transcription-coupled nucleotide excision repair (tc-ner)
(R-MMU-6781827)
Transcriptional regulation by tp53
(R-MMU-3700989)
3'-5' dna helicase activity
(GO:0043138)
Apoptotic process
(GO:0006915)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna helicase activity
(GO:0003678)
Dna repair
(GO:0006281)
Dna topological change
(GO:0006265)
Embryonic organ development
(GO:0048568)
Hair cell differentiation
(GO:0035315)
Helicase activity
(GO:0004386)
Hydrolase activity
(GO:0016787)
Nucleoplasm
(GO:0005654)
Nucleotide-excision repair
(GO:0006289)
Nucleotide-excision repair, dna duplex unwinding
(GO:0000717)
Nucleotide-excision repair factor 3 complex
(GO:0000112)
Nucleotide binding
(GO:0000166)
Nucleus
(GO:0005634)
Positive regulation of apoptotic process
(GO:0043065)
Promoter-specific chromatin binding
(GO:1990841)
Protein localization
(GO:0008104)
Regulation of mitotic cell cycle phase transition
(GO:1901990)
Response to oxidative stress
(GO:0006979)
Response to uv
(GO:0009411)
Transcription-coupled nucleotide-excision repair
(GO:0006283)
Transcription by rna polymerase ii
(GO:0006366)
Transcription elongation by rna polymerase i
(GO:0006362)
Transcription factor tfiid complex
(GO:0005669)
Transcription factor tfiih core complex
(GO:0000439)
Transcription factor tfiih holo complex
(GO:0005675)
Transcription initiation at rna polymerase ii promoter
(GO:0006367)
Transcription preinitiation complex
(GO:0097550)
Uv protection
(GO:0009650)

Other Information

Proteins

General transcription and DNA repair factor IIH helicase subunit XPB

Genular Protein ID: 3924594488

Symbol: ERCC3_MOUSE

Name: General transcription and DNA repair factor IIH helicase subunit XPB

UniProtKB Accession Codes:

P49135

Database IDs:

Citations:

PubMed ID: 1747940

Title: Characterization of the mouse homolog of the XPBC/ERCC-3 gene implicated in xeroderma pigmentosum and Cockayne's syndrome.

PubMed ID: 1747940

DOI: 10.1093/carcin/12.12.2361

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 783
Mass: 89126
Checksum: 6D204EF6A831D8AF
Sequence:

MGKRDRVDRD KKKSKKRQYE EEEEDEDDIP GNESQEAVPS AAGKQVDESS TKVDEYGAKD 
YRQQMPLKGD HTSRPLWVAP DGHIFLEAFS PVYKYAQDFL VAIAEPVCRP THVHEYKLTA 
YSLYAAVSVG LQTSDITEYL RKLSKTGVPD GIIQFIKLCT VSYGKVKLVL KHNRYFVESS 
HPDVIQHLLQ DPVIRECRLR NAEGEATELI TETFTSKSAI SKTAAEGSGG PSTSQGVDAQ 
ATSDIPKDLF DFYEQMDKDE EEEEETQTVS FEVKQEMIEE LQKRCICLEY PLLAEYDFRN 
DTLNPDINID LKPTAVLRPY QEKSLRKMFG NGRARSGVIV LPCGAGKSLV GVTAACTVRK 
RCLVLGNSAV SVEQWKAQFK MWSTIDDSQI CRFTSDAKDK PIGCSVAIST YSMLGHTTKR 
SWEAERVMEW LKTQEWGLMI LDEVHTIPAR MFRRVLTIVQ AHCKLGLTAT LVREDDKIVD 
LNFLIGPKLY EANWMELQNN GYIAKVQCAE VWCPMSPEFY REYVAIKTKK RILLYTMNPN 
KFRACQFLIK FHERRNDKII VFADNVFALK EYAIRLNKPY IYGPTSQGER MQILQNFKHN 
PKINTIFISK VGDTSFDLPE ANVLIQISSH GGSRRQEAQR LGRVLRAKKG MVAEEYNAFF 
YSLVSQDTQE MAYSTKRQRF LVDQGYSFKV ITKLAGMEEE ELAFSTKEEQ QQLLQKVLAA 
TDLDAEEEVV AGEFGSRSGQ ASRRCGTMSS LSGADDTVYM EYHSSRSKAS SKHVHPLFKR 
FRK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.