AAMP - ENSG00000127837

Details for: AAMP

Gene ID: 14

Symbol: AAMP

Ensembl ID: ENSG00000127837

Description: angio associated migratory cell protein

Associated with

Hemostasis (R-HSA-109582)
Immune system (R-HSA-168256)
Innate immune system (R-HSA-168249)
Nod1/2 signaling pathway (R-HSA-168638)
Nucleotide-binding domain, leucine rich repeat containing receptor (nlr) signaling pathways (R-HSA-168643)
Platelet activation, signaling and aggregation (R-HSA-76002)
Signal amplification (R-HSA-392518)
Signaling by egfr (R-HSA-177929)
Signaling by receptor tyrosine kinases (R-HSA-9006934)
Signaling by vegf (R-HSA-194138)
Signal transduction (R-HSA-162582)
Thromboxane signalling through tp receptor (R-HSA-428930)
Angiogenesis (GO:0001525)
Cell differentiation (GO:0030154)
Cell surface (GO:0009986)
Cytosol (GO:0005829)
Heparin binding (GO:0008201)
Intercellular bridge (GO:0045171)
Microtubule cytoskeleton (GO:0015630)
Plasma membrane (GO:0005886)
Positive regulation of endothelial cell migration (GO:0010595)
Protein binding (GO:0005515)
Smooth muscle cell migration (GO:0014909)

Cells (max top 100)

Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.96
Marker Score: 7695
Cell Name: decidual cell (CL2000002)
Fold Change: 1.9
Marker Score: 8214
Cell Name: mesodermal cell (CL0000222)
Fold Change: 1.83
Marker Score: 24092
Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.71
Marker Score: 14746
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.7
Marker Score: 11046
Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.68
Marker Score: 6222
Cell Name: kidney cell (CL1000497)
Fold Change: 1.68
Marker Score: 1121
Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.66
Marker Score: 3469.5
Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.63
Marker Score: 3306
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.59
Marker Score: 1687
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.59
Marker Score: 6140
Cell Name: Unknown (CL0002371)
Fold Change: 1.58
Marker Score: 1677
Cell Name: stem cell (CL0000034)
Fold Change: 1.58
Marker Score: 3743
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.57
Marker Score: 2314
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.56
Marker Score: 9955
Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.55
Marker Score: 2544
Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.53
Marker Score: 3469
Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.53
Marker Score: 4154
Cell Name: granulosa cell (CL0000501)
Fold Change: 1.52
Marker Score: 15344
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.52
Marker Score: 3712.5
Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.52
Marker Score: 1196
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.52
Marker Score: 51603
Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.51
Marker Score: 833
Cell Name: pro-T cell (CL0000827)
Fold Change: 1.49
Marker Score: 6110
Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.45
Marker Score: 1465
Cell Name: Leydig cell (CL0000178)
Fold Change: 1.45
Marker Score: 1567
Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.45
Marker Score: 1822
Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.44
Marker Score: 337
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.44
Marker Score: 2442
Cell Name: colon epithelial cell (CL0011108)
Fold Change: 1.42
Marker Score: 4450
Cell Name: enterocyte (CL0000584)
Fold Change: 1.4
Marker Score: 6739
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.38
Marker Score: 10267
Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.37
Marker Score: 3235
Cell Name: Hofbauer cell (CL3000001)
Fold Change: 1.37
Marker Score: 756
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.37
Marker Score: 6715
Cell Name: epithelial cell (CL0000066)
Fold Change: 1.36
Marker Score: 2170
Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.36
Marker Score: 506
Cell Name: oogonial cell (CL0000024)
Fold Change: 1.34
Marker Score: 1932
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.31
Marker Score: 14776
Cell Name: plasmablast (CL0000980)
Fold Change: 1.31
Marker Score: 1738
Cell Name: peptic cell (CL0000155)
Fold Change: 1.3
Marker Score: 546
Cell Name: cell in vitro (CL0001034)
Fold Change: 1.3
Marker Score: 45092
Cell Name: pneumocyte (CL0000322)
Fold Change: 1.29
Marker Score: 2070
Cell Name: keratinocyte (CL0000312)
Fold Change: 1.28
Marker Score: 1069.5
Cell Name: blood cell (CL0000081)
Fold Change: 1.28
Marker Score: 14854
Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1.26
Marker Score: 794
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.25
Marker Score: 1508
Cell Name: proerythroblast (CL0000547)
Fold Change: 1.24
Marker Score: 839
Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.24
Marker Score: 7334
Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.23
Marker Score: 1161.5
Cell Name: supporting cell (CL0000630)
Fold Change: 1.22
Marker Score: 2296
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 1.22
Marker Score: 9526
Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.21
Marker Score: 3298
Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 1.2
Marker Score: 2342
Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.2
Marker Score: 1699
Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.19
Marker Score: 1121
Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.19
Marker Score: 1122
Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 1.19
Marker Score: 423
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 1.19
Marker Score: 284
Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.18
Marker Score: 1328
Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.18
Marker Score: 785
Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 1.18
Marker Score: 300
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.17
Marker Score: 1212
Cell Name: neural crest cell (CL0011012)
Fold Change: 1.16
Marker Score: 1242
Cell Name: stromal cell (CL0000499)
Fold Change: 1.16
Marker Score: 1355
Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.15
Marker Score: 1765.5
Cell Name: adventitial cell (CL0002503)
Fold Change: 1.15
Marker Score: 283
Cell Name: Unknown (CL0000548)
Fold Change: 1.15
Marker Score: 835
Cell Name: lung ciliated cell (CL1000271)
Fold Change: 1.14
Marker Score: 542
Cell Name: theca cell (CL0000503)
Fold Change: 1.14
Marker Score: 818
Cell Name: lung secretory cell (CL1000272)
Fold Change: 1.14
Marker Score: 1015
Cell Name: club cell (CL0000158)
Fold Change: 1.13
Marker Score: 1325
Cell Name: preosteoblast (CL0007010)
Fold Change: 1.13
Marker Score: 321
Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 1.13
Marker Score: 222
Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 1.12
Marker Score: 706
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.12
Marker Score: 3321
Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 1.11
Marker Score: 1346
Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 1.11
Marker Score: 507
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.1
Marker Score: 1957
Cell Name: male germ cell (CL0000015)
Fold Change: 1.1
Marker Score: 318
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.1
Marker Score: 2957.5
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 1.1
Marker Score: 981
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.1
Marker Score: 1860.5
Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.1
Marker Score: 1113
Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 1.1
Marker Score: 266
Cell Name: intestine goblet cell (CL0019031)
Fold Change: 1.1
Marker Score: 1050
Cell Name: eukaryotic cell (CL0000255)
Fold Change: 1.1
Marker Score: 564
Cell Name: osteoclast (CL0000092)
Fold Change: 1.09
Marker Score: 544
Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 1.09
Marker Score: 378
Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 1.09
Marker Score: 350
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.09
Marker Score: 2485
Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.09
Marker Score: 444
Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 1.09
Marker Score: 345
Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.08
Marker Score: 571
Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 1.08
Marker Score: 2722
Cell Name: basal cell (CL0000646)
Fold Change: 1.08
Marker Score: 1389
Cell Name: secretory cell (CL0000151)
Fold Change: 1.08
Marker Score: 1963
Cell Name: neural cell (CL0002319)
Fold Change: 1.07
Marker Score: 518
Cell Name: mucus secreting cell (CL0000319)
Fold Change: 1.07
Marker Score: 273
Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 1.07
Marker Score: 552

**Key characteristics:** * AAMP is a transmembrane protein that is expressed in a variety of cell types. * It is a member of the Angiogenesis factor family of proteins. * AAMP is a key regulator of angiogenesis, the process by which new blood vessels form. * It is also involved in cell differentiation, cytosol, and hemostasis. **Pathways and functions:** * AAMP is involved in the regulation of vascularization by binding to the VEGFR-2 receptor and promoting its activation. * It also binds to the EGF receptor and promotes its activation, which is important for the migration of endothelial cells. * AAMP is involved in the regulation of cell differentiation by promoting the expression of endothelial cell markers. * It is also involved in the regulation of apoptosis by binding to the Apaf-1 receptor and promoting its degradation. **Clinical significance:** * Mutations in the AAMP gene have been linked to a number of human diseases, including placental abruption, miscarriage, and preeclampsia. * AAMP is a promising target for the treatment of these diseases. **Additional information:** * AAMP is a protein that is highly conserved across species. * It is a secreted protein that is produced by endothelial cells. * It is a potent angiogenic factor that can induce the migration of endothelial cells in vitro.

Database document:

Only first 5 entries are kept for 'singleCellExpressions', 'mRNAExpressions' and other large data arrays.