Details for: ADORA3

Gene ID: 140

Symbol: ADORA3

Ensembl ID: ENSG00000282608

Description: adenosine A3 receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 3.8970
    Cell Significance Index: 10.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.9081
    Cell Significance Index: 29.0900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.8457
    Cell Significance Index: 12.7500
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.8230
    Cell Significance Index: 12.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7927
    Cell Significance Index: 22.8400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.4389
    Cell Significance Index: 6.7900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1439
    Cell Significance Index: 8.6400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0895
    Cell Significance Index: 14.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0070
    Cell Significance Index: -5.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0079
    Cell Significance Index: -6.0000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0083
    Cell Significance Index: -6.1100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0088
    Cell Significance Index: -4.9400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0097
    Cell Significance Index: -6.0800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0114
    Cell Significance Index: -1.9400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0143
    Cell Significance Index: -5.1300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0261
    Cell Significance Index: -4.7100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0280
    Cell Significance Index: -5.9000
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0359
    Cell Significance Index: -0.5300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0406
    Cell Significance Index: -8.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0454
    Cell Significance Index: -5.5800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0480
    Cell Significance Index: -6.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0512
    Cell Significance Index: -5.2300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0576
    Cell Significance Index: -3.9900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0597
    Cell Significance Index: -6.8400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0607
    Cell Significance Index: -1.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0655
    Cell Significance Index: -1.4200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0770
    Cell Significance Index: -2.0600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0799
    Cell Significance Index: -6.1300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0829
    Cell Significance Index: -10.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0836
    Cell Significance Index: -6.2300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0890
    Cell Significance Index: -12.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0935
    Cell Significance Index: -6.0300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0970
    Cell Significance Index: -4.5600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1012
    Cell Significance Index: -1.4700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1040
    Cell Significance Index: -2.2200
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1048
    Cell Significance Index: -1.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1165
    Cell Significance Index: -6.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1294
    Cell Significance Index: -6.7200
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1407
    Cell Significance Index: -1.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1429
    Cell Significance Index: -16.8500
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.1455
    Cell Significance Index: -1.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1580
    Cell Significance Index: -5.4900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1718
    Cell Significance Index: -6.0200
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.2069
    Cell Significance Index: -4.2100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2082
    Cell Significance Index: -5.3200
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.2142
    Cell Significance Index: -2.6500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2166
    Cell Significance Index: -6.2100
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.2240
    Cell Significance Index: -2.0500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2360
    Cell Significance Index: -5.9000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2371
    Cell Significance Index: -11.9800
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.2437
    Cell Significance Index: -2.8800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2538
    Cell Significance Index: -4.6900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2601
    Cell Significance Index: -6.8400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.2634
    Cell Significance Index: -6.3800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2642
    Cell Significance Index: -8.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2669
    Cell Significance Index: -16.8200
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.2755
    Cell Significance Index: -7.0200
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.2809
    Cell Significance Index: -4.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2812
    Cell Significance Index: -17.2900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2850
    Cell Significance Index: -13.2900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2963
    Cell Significance Index: -12.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2975
    Cell Significance Index: -9.7400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3359
    Cell Significance Index: -8.3800
  • Cell Name: PP cell (CL0000696)
    Fold Change: -0.3363
    Cell Significance Index: -3.4200
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.3384
    Cell Significance Index: -4.6400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3480
    Cell Significance Index: -6.1500
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.3481
    Cell Significance Index: -2.8200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3580
    Cell Significance Index: -6.0300
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.3589
    Cell Significance Index: -4.2200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3633
    Cell Significance Index: -6.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3637
    Cell Significance Index: -12.7800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3644
    Cell Significance Index: -9.7300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.3647
    Cell Significance Index: -6.0100
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.3693
    Cell Significance Index: -3.7700
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.3720
    Cell Significance Index: -4.0000
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: -0.3745
    Cell Significance Index: -3.5600
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: -0.3748
    Cell Significance Index: -1.5600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.3762
    Cell Significance Index: -5.2800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3781
    Cell Significance Index: -8.1700
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.3810
    Cell Significance Index: -7.4500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.3810
    Cell Significance Index: -4.9300
  • Cell Name: glial cell (CL0000125)
    Fold Change: -0.3815
    Cell Significance Index: -4.1800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3822
    Cell Significance Index: -14.0300
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.3852
    Cell Significance Index: -4.3100
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.3941
    Cell Significance Index: -3.5600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3944
    Cell Significance Index: -5.9100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4001
    Cell Significance Index: -8.3500
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.4019
    Cell Significance Index: -6.8700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4038
    Cell Significance Index: -5.9600
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.4190
    Cell Significance Index: -4.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4193
    Cell Significance Index: -6.1900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4349
    Cell Significance Index: -8.6000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.4427
    Cell Significance Index: -6.2100
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.4435
    Cell Significance Index: -5.6200
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.4543
    Cell Significance Index: -5.6900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.4560
    Cell Significance Index: -5.8400
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.4602
    Cell Significance Index: -6.8900
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.4708
    Cell Significance Index: -6.5300
  • Cell Name: podocyte (CL0000653)
    Fold Change: -0.4725
    Cell Significance Index: -5.4200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4850
    Cell Significance Index: -8.3900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ADORA3 is a GPCR that belongs to the class A/1 receptor family, which is characterized by a rhodopsin-like structure. This receptor is activated by adenosine, a purine nucleoside that plays a crucial role in various cellular processes. ADORA3 is unique in that it is the only member of the adenosine receptor family that is coupled to the Gi protein, which inhibits adenylate cyclase activity. This leads to a decrease in intracellular cAMP levels, resulting in a range of downstream effects. **Pathways and Functions:** ADORA3 is involved in several signaling pathways, including: 1. **Activation of adenylate cyclase activity**: ADORA3 activation leads to the inhibition of adenylate cyclase, resulting in a decrease in cAMP levels. 2. **G alpha (i) signaling events**: ADORA3 activation triggers the activation of the Gi protein, which inhibits adenylate cyclase activity. 3. **G protein-coupled adenosine receptor activity**: ADORA3 is a member of the GPCR family and is activated by adenosine, leading to a range of downstream effects. 4. **Inflammatory response**: ADORA3 has been implicated in the regulation of inflammatory responses, particularly in the context of cardiovascular disease. 5. **Negative regulation of cell migration**: ADORA3 activation has been shown to inhibit cell migration, which is important in the context of cancer and cardiovascular disease. 6. **Negative regulation of cell population proliferation**: ADORA3 activation has also been shown to inhibit cell proliferation, which is important in the context of cancer. 7. **Negative regulation of NF-κB transcription factor activity**: ADORA3 activation has been shown to inhibit the activity of the NF-κB transcription factor, which is involved in inflammation and immune responses. **Clinical Significance:** ADORA3 has been implicated in various clinical conditions, including: 1. **Cardiovascular disease**: ADORA3 has been shown to play a role in the regulation of heart contraction and norepinephrine secretion, making it a potential target for the treatment of cardiovascular disease. 2. **Inflammatory disorders**: ADORA3 has been implicated in the regulation of inflammatory responses, making it a potential target for the treatment of inflammatory disorders, such as rheumatoid arthritis and atherosclerosis. 3. **Cancer**: ADORA3 has been shown to inhibit cell migration and proliferation, making it a potential target for the treatment of cancer. 4. **Neurological disorders**: ADORA3 has been implicated in the regulation of neurotransmitter release, making it a potential target for the treatment of neurological disorders, such as Parkinson's disease and Alzheimer's disease. In conclusion, ADORA3 is a complex receptor that plays a crucial role in various physiological and pathological processes. Its unique structure and signaling pathways make it a potential target for the treatment of various clinical conditions. Further research is needed to fully understand the roles of ADORA3 and to explore its therapeutic potential.

Genular Protein ID: 2357870480

Symbol: AA3R_HUMAN

Name: Adenosine receptor A3

UniProtKB Accession Codes:

P0DMS8 A2A3P4 P33765 Q6UWU0 Q9BYZ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 DNASU 1 DisGeNET 1 DrugBank 6 DrugCentral 1 EMBL 9 EMDB 2 Ensembl 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PeptideAtlas 1 Pfam 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 VEuPathDB 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8399349

Title: cDNA cloning and sequence analysis of the human A3 adenosine receptor.

PubMed ID: 8399349

DOI: 10.1016/0167-4889(93)90077-3

PubMed ID: 8234299

Title: Molecular cloning and characterization of the human A3 adenosine receptor.

PubMed ID: 8234299

DOI: 10.1073/pnas.90.21.10365

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11214319

Title: Molecular phylogenetics and the origins of placental mammals.

PubMed ID: 11214319

DOI: 10.1038/35054550

PubMed ID: 27886186

Title: Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-kappaB and osteosarcoma progression.

PubMed ID: 27886186

DOI: 10.1038/ncomms13561

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 318
  • Mass: 36185
  • Checksum: 690E67986130FC28
  • Sequence:
    • MPNNSTALSL ANVTYITMEI FIGLCAIVGN VLVICVVKLN PSLQTTTFYF IVSLALADIA 
VGVLVMPLAI VVSLGITIHF YSCLFMTCLL LIFTHASIMS LLAIAVDRYL RVKLTVRYKR 
VTTHRRIWLA LGLCWLVSFL VGLTPMFGWN MKLTSEYHRN VTFLSCQFVS VMRMDYMVYF 
SFLTWIFIPL VVMCAIYLDI FYIIRNKLSL NLSNSKETGA FYGREFKTAK SLFLVLFLFA 
LSWLPLSIIN CIIYFNGEVP QLVLYMGILL SHANSMMNPI VYAYKIKKFK ETYLLILKAC 
VVCHPSDSLD TSIEKNSE

Genular Protein ID: 986028626

Symbol: A0A0J9YWR0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0J9YWR0

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 3 Pfam 1 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 123
  • Mass: 13255
  • Checksum: 9D7A47447562C05C
  • Sequence:
    • MPNNSTALSL ANVTYITMEI FIGLCAIVGN VLVICVVKLN PSLQTTTFYF IVSLALADIA 
VGVLVMPLAI VVSLGITIHF YSCLFMTCLL LIFTHASIMS LLAIAVDRYL RVKLTVSSIS 
PTL

Genular Protein ID: 333592506

Symbol: H6VQ59_HUMAN

Name: N/A

UniProtKB Accession Codes:

H6VQ59

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 RefSeq 2 RuleBase 1 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 317
  • Mass: 36053
  • Checksum: 716EE66158D21E11
  • Sequence:
    • PNNSTALSLA NVTYITMEIF IGLCAIVGNV LVICVVKLNP SLQTTTFYFI VSLALADIAV 
GVLVMPLAIV VSLGITIHFY SCLFMTCLLL IFTHASIMSL LAIAVDRYLR VKLTVRYKRV 
TTHRRIWLAL GLCWLVSFLV GLTPMFGWNM KLTSEYHRNV TFLSCQFVSV MRMDYMVYFS 
FLTWIFIPLV VMCAIYLDIF YIIRNKLSLN LSNSKETGAF YGREFKTAKS LFLVLFLFAL 
SWLPLSIINC IIYFNGEVPQ LVLYMGILLS HANSMMNPIV YAYKIKKFKE TYLLILKACV 
VCHPSDSLDT SIEKNSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.