Ext1 | ENSMUSG00000061731 | NCBI 14042

Details for: Ext1

Gene ID: 14042

Symbol: Ext1

Ensembl ID: ENSMUSG00000061731

Description: exostosin glycosyltransferase 1

Associated with

Glycosaminoglycan metabolism
(R-MMU-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-MMU-1638091)
Hs-gag biosynthesis
(R-MMU-2022928)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Acetylglucosaminyltransferase activity
(GO:0008375)
Antigen processing and presentation
(GO:0019882)
Axon guidance
(GO:0007411)
Blood vessel remodeling
(GO:0001974)
Bmp signaling pathway
(GO:0030509)
Bone resorption
(GO:0045453)
Brain development
(GO:0007420)
Cell adhesion
(GO:0007155)
Cell adhesion mediated by integrin
(GO:0033627)
Cell fate commitment
(GO:0045165)
Cell morphogenesis
(GO:0000902)
Cell population proliferation
(GO:0008283)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular component organization
(GO:0016043)
Cellular response to fibroblast growth factor stimulus
(GO:0044344)
Chemokine production
(GO:0032602)
Chondrocyte differentiation
(GO:0002062)
Chondrocyte hypertrophy
(GO:0003415)
Chondrocyte proliferation
(GO:0035988)
Chondroitin sulfate metabolic process
(GO:0030204)
Collagen fibril organization
(GO:0030199)
Dendritic cell migration
(GO:0036336)
Embryonic morphogenesis
(GO:0048598)
Endochondral bone growth
(GO:0003416)
Endochondral ossification
(GO:0001958)
Endoderm development
(GO:0007492)
Fear response
(GO:0042596)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Fluid transport
(GO:0042044)
Gastrulation
(GO:0007369)
Gene expression
(GO:0010467)
Glandular epithelial cell differentiation
(GO:0002067)
Glomerular basement membrane development
(GO:0032836)
Glucuronosyl-n-acetylglucosaminyl-proteoglycan 4-alpha-n-acetylglucosaminyltransferase activity
(GO:0050508)
Glucuronosyltransferase activity
(GO:0015020)
Glycosaminoglycan biosynthetic process
(GO:0006024)
Glycosyltransferase activity
(GO:0016757)
Hair cycle process
(GO:0022405)
Hair follicle morphogenesis
(GO:0031069)
Heart field specification
(GO:0003128)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Heparan sulfate proteoglycan biosynthetic process
(GO:0015012)
Heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
(GO:0015014)
Heparin biosynthetic process
(GO:0030210)
Heparin metabolic process
(GO:0030202)
Hypersensitivity
(GO:0002524)
Leukocyte tethering or rolling
(GO:0050901)
Limb joint morphogenesis
(GO:0036022)
Lymphocyte adhesion to endothelial cell of high endothelial venule
(GO:0036339)
Mesoderm development
(GO:0007498)
Metal ion binding
(GO:0046872)
Multicellular organismal-level water homeostasis
(GO:0050891)
Multicellular organism growth
(GO:0035264)
N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
(GO:0050509)
Neural crest cell differentiation
(GO:0014033)
Neuron projection development
(GO:0031175)
Olfactory bulb development
(GO:0021772)
Optic nerve development
(GO:0021554)
Ossification
(GO:0001503)
Ossification involved in bone maturation
(GO:0043931)
Polysaccharide biosynthetic process
(GO:0000271)
Protein catabolic process
(GO:0030163)
Protein glycosylation
(GO:0006486)
Protein heterodimerization activity
(GO:0046982)
Protein homodimerization activity
(GO:0042803)
Proteoglycan biosynthetic process
(GO:0030166)
Regulation of blood pressure
(GO:0008217)
Regulation of tumor necrosis factor-mediated signaling pathway
(GO:0010803)
Response to light intensity
(GO:0009642)
Response to virus
(GO:0009615)
Sebaceous gland development
(GO:0048733)
Smoothened signaling pathway
(GO:0007224)
Social behavior
(GO:0035176)
Sodium ion homeostasis
(GO:0055078)
Stem cell division
(GO:0017145)
Sulfation
(GO:0051923)
Synaptic transmission, glutamatergic
(GO:0035249)
Transferase activity
(GO:0016740)
Vacuole organization
(GO:0007033)
Vasodilation
(GO:0042311)
Wound healing
(GO:0042060)

Other Information

Proteins

Multiple exostoses protein 1 homolog

Genular Protein ID: 1321505687

Symbol: EXT1_MOUSE

Name: Multiple exostoses protein 1 homolog

UniProtKB Accession Codes:

P97464 Q61546

Database IDs:

Citations:

PubMed ID: 9186511

Title: The murine Ext1 gene shows a high level of sequence similarity with its human homologue and is part of a conserved linkage group on chromosome 15.

PubMed ID: 9186511

DOI: 10.1159/000134536

PubMed ID: 9254013

Title: Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for hereditary multiple exostoses.

PubMed ID: 9254013

DOI: 10.3109/10425179709034035

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9703997

Title: Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene.

PubMed ID: 9703997

DOI: 10.1006/bbrc.1998.9050

Sequence Information:

Length: 746
Mass: 86308
Checksum: 5AC7F24BECEEDFF9
Sequence:

MQAKKRYFIL LSAGSCLALL FYFGGVQFRA SRSHSRREEH SGRNGLHQPS PDHFWPRFPD 
ALRPFFPWDQ LENEDSSVHI SPRQKRDANS SIYKGKKCRM ESCFDFTLCK KNGFKVYVYP 
QQKGEKIAES YQNILAAIEG SRFYTSDPSQ ACLFVLSLDT LDRDQLSPQY VHNLRSKVQS 
LHLWNNGRNH LIFNLYSGTW PDYTEDVGFD IGQAMLAKAS ISTENFRPNF DVSIPLFSKD 
HPRTGGERGF LKFNTIPPLR KYMLVFKGKR YLTGIGSDTR NALYHVHNGE DVLLLTTCKH 
GKDWQKHKDS RCDRDNTEYE KYDYREMLHN ATFCLVPRGR RLGSFRFLEA LQAACVPVML 
SNGWELPFSE VINWNQAAVI GDERLLLQIP STIRSIHQDK ILALRQQTQF LWEAYFSSVE 
KIVLTTLEII QDRIFKHISR NSLIWNKHPG GLFVLPQYSS YLGDFPYYYA NLGLKPPSKF 
TAVIHAVTPL VSQSQPVLKL LVAAAKSQYC AQIIVLWNCD KPLPAKHRWP ATAVPVIVIE 
GESKVMSSRF LPYDNIITDA VLSLDEDTVL STTEVDFAFT VWQSFPERIV GYPARSHFWD 
NSKERWGYTS KWTNDYSMVL TGAAIYHKYY HYLYSHYLPA SLKNMVDQLA NCEDILMNFL 
VSAVTKLPPI KVTQKKQYKE TMMGQTSRAS RWADPDHFAQ RQSCMNTFAS WFGYMPLIHS 
QMRLDPVLFK DQVSILRKKY RDIERL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ext1

Associated with

Other Information

The murine Ext1 gene shows a high level of sequence similarity with its human homologue and is part of a conserved linkage group on chromosome 15. PubMed ID: 9186511

Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for hereditary multiple exostoses. PubMed ID: 9254013

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene. PubMed ID: 9703997

Database document:

PubMed ID: 9186511

PubMed ID: 9254013

PubMed ID: 15489334

PubMed ID: 9703997