Details for: CRY2

Gene ID: 1408

Symbol: CRY2

Ensembl ID: ENSG00000121671

Description: cryptochrome circadian regulator 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 167.7326
    Cell Significance Index: -26.0900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 104.0437
    Cell Significance Index: -26.3900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 55.4517
    Cell Significance Index: -26.1800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.6022
    Cell Significance Index: -21.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.3725
    Cell Significance Index: -21.3600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.5498
    Cell Significance Index: -26.5700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.2987
    Cell Significance Index: -24.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.7916
    Cell Significance Index: -26.8000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 3.3174
    Cell Significance Index: 25.5700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.2270
    Cell Significance Index: 40.0300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.0353
    Cell Significance Index: 106.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5208
    Cell Significance Index: 305.0700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.1784
    Cell Significance Index: 19.8500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.1378
    Cell Significance Index: 78.6900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 1.1245
    Cell Significance Index: 14.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1104
    Cell Significance Index: 15.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.9377
    Cell Significance Index: 1765.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9073
    Cell Significance Index: 69.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8694
    Cell Significance Index: 172.5500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8591
    Cell Significance Index: 775.6800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7140
    Cell Significance Index: 83.2100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6567
    Cell Significance Index: 235.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6273
    Cell Significance Index: 13.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5862
    Cell Significance Index: 25.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5778
    Cell Significance Index: 26.1900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5152
    Cell Significance Index: 83.7900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5138
    Cell Significance Index: 34.5500
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.5074
    Cell Significance Index: 4.4700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5006
    Cell Significance Index: 9.7700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4990
    Cell Significance Index: 18.9000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4933
    Cell Significance Index: 53.6600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3949
    Cell Significance Index: 23.7100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3386
    Cell Significance Index: 17.5900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3252
    Cell Significance Index: 8.1300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.3077
    Cell Significance Index: 8.7800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2361
    Cell Significance Index: 42.5600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2054
    Cell Significance Index: 20.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1714
    Cell Significance Index: 7.9900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1605
    Cell Significance Index: 19.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1571
    Cell Significance Index: 4.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1448
    Cell Significance Index: 196.9300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1358
    Cell Significance Index: 25.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1334
    Cell Significance Index: 3.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1308
    Cell Significance Index: 57.8100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1299
    Cell Significance Index: 89.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1215
    Cell Significance Index: 7.4700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1173
    Cell Significance Index: 74.4900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1010
    Cell Significance Index: 1.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0981
    Cell Significance Index: 44.5300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0973
    Cell Significance Index: 6.1300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0958
    Cell Significance Index: 9.9700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0816
    Cell Significance Index: 2.3400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0790
    Cell Significance Index: 10.8500
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.0730
    Cell Significance Index: 0.8900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0730
    Cell Significance Index: 39.8600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0718
    Cell Significance Index: 132.3900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0697
    Cell Significance Index: 2.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0566
    Cell Significance Index: 87.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0523
    Cell Significance Index: 8.9300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0481
    Cell Significance Index: 0.7100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0076
    Cell Significance Index: 0.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0040
    Cell Significance Index: 0.5800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0045
    Cell Significance Index: -0.5800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0086
    Cell Significance Index: -6.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0164
    Cell Significance Index: -0.9200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0211
    Cell Significance Index: -15.6600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0216
    Cell Significance Index: -1.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0260
    Cell Significance Index: -19.6900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0378
    Cell Significance Index: -21.3400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0439
    Cell Significance Index: -4.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0452
    Cell Significance Index: -28.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0526
    Cell Significance Index: -6.7900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0528
    Cell Significance Index: -2.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0654
    Cell Significance Index: -1.7800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0773
    Cell Significance Index: -22.2400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0906
    Cell Significance Index: -1.0800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0992
    Cell Significance Index: -2.4200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1086
    Cell Significance Index: -2.9100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1220
    Cell Significance Index: -1.8000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1221
    Cell Significance Index: -14.4000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1243
    Cell Significance Index: -26.1800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1302
    Cell Significance Index: -14.9200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1559
    Cell Significance Index: -3.7400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1667
    Cell Significance Index: -3.5500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1728
    Cell Significance Index: -4.8300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1955
    Cell Significance Index: -5.2200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2234
    Cell Significance Index: -4.6400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.2331
    Cell Significance Index: -3.2600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.2415
    Cell Significance Index: -3.9800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2480
    Cell Significance Index: -11.6600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2504
    Cell Significance Index: -8.0200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2521
    Cell Significance Index: -19.9700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2613
    Cell Significance Index: -16.8600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2967
    Cell Significance Index: -4.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3110
    Cell Significance Index: -6.6000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3331
    Cell Significance Index: -20.4200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3754
    Cell Significance Index: -8.2200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3906
    Cell Significance Index: -10.2700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3915
    Cell Significance Index: -6.7700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4059
    Cell Significance Index: -17.6500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CRY2 is a member of the cryptochrome family of proteins, which are known for their ability to detect blue light and respond to it by regulating gene expression. CRY2 is a dimeric protein composed of two identical subunits, each with a conserved FAD-binding domain. The protein is highly expressed in photoreceptor cells of the retina, as well as in other tissues such as the brain, gonads, and endocrine system. CRY2 has been shown to interact with various proteins, including transcription factors, kinases, and phosphatases, to regulate gene expression and maintain circadian homeostasis. **Pathways and Functions:** CRY2 is involved in several key pathways that regulate circadian rhythms, including: 1. **Blue Light Signaling Pathway:** CRY2 responds to blue light by regulating the expression of clock genes, such as PER2 and BMAL1, which are essential for maintaining circadian rhythms. 2. **Circadian Clock:** CRY2 interacts with other clock proteins, such as PER3 and CLOCK, to regulate the expression of clock genes and maintain circadian homeostasis. 3. **DNA Repair:** CRY2 has been shown to have photolyase activity, which allows it to repair DNA damage caused by blue light exposure. 4. **Glucose Homeostasis:** CRY2 has been implicated in the regulation of glucose metabolism, with studies showing that it regulates the expression of genes involved in glucose uptake and storage. **Clinical Significance:** Dysregulation of CRY2 has been implicated in various diseases and disorders, including: 1. **Circadian Rhythm Disorders:** CRY2 dysfunction has been linked to disorders such as delayed sleep phase syndrome, non-24-hour sleep-wake disorder, and jet lag. 2. **Diabetes:** CRY2 has been shown to regulate glucose metabolism, and its dysregulation has been implicated in the development of type 2 diabetes. 3. **Neurodegenerative Diseases:** CRY2 has been implicated in the regulation of neuroinflammation and neurodegeneration, with studies showing that it regulates the expression of genes involved in these processes. 4. **Cancer:** CRY2 has been shown to regulate cell cycle progression and apoptosis, with studies suggesting that its dysregulation may contribute to the development of cancer. In conclusion, CRY2 is a critical gene that plays a pivotal role in the regulation of circadian rhythms and beyond. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of understanding the mechanisms of CRY2 in maintaining health and preventing disease.

Genular Protein ID: 889958176

Symbol: CRY2_HUMAN

Name: Cryptochrome-2

UniProtKB Accession Codes:

Q49AN0 B4DH32 B4DZD6 O75148 Q8IV71

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 34 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8909283

Title: Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.

PubMed ID: 8909283

DOI: 10.1021/bi962209o

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 9801304

Title: Characterization of photolyase/blue-light receptor homologs in mouse and human cells.

PubMed ID: 9801304

DOI: 10.1093/nar/26.22.5086

PubMed ID: 10531061

Title: Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

PubMed ID: 10531061

DOI: 10.1126/science.286.5440.768

PubMed ID: 11889036

Title: Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.

PubMed ID: 11889036

DOI: 10.1093/emboj/21.6.1301

PubMed ID: 14672706

Title: A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation.

PubMed ID: 14672706

DOI: 10.1016/j.bbrc.2003.11.099

PubMed ID: 16790549

Title: Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5.

PubMed ID: 16790549

DOI: 10.1073/pnas.0604138103

PubMed ID: 17463251

Title: SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.

PubMed ID: 17463251

DOI: 10.1126/science.1141194

PubMed ID: 22798407

Title: Identification of small molecule activators of cryptochrome.

PubMed ID: 22798407

DOI: 10.1126/science.1223710

PubMed ID: 23303907

Title: Metabolism and the circadian clock converge.

PubMed ID: 23303907

DOI: 10.1152/physrev.00016.2012

PubMed ID: 23916625

Title: Molecular architecture of the mammalian circadian clock.

PubMed ID: 23916625

DOI: 10.1016/j.tcb.2013.07.002

PubMed ID: 26569474

Title: A magnetic protein biocompass.

PubMed ID: 26569474

DOI: 10.1038/nmat4484

PubMed ID: 30530698

Title: Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.

PubMed ID: 30530698

DOI: 10.1073/pnas.1816411115

PubMed ID: 31138685

Title: TIMELESS mutation alters phase responsiveness and causes advanced sleep phase.

PubMed ID: 31138685

DOI: 10.1073/pnas.1819110116

Sequence Information:

  • Length: 593
  • Mass: 66947
  • Checksum: BF380424092BEBFB
  • Sequence:
    • MAATVATAAA VAPAPAPGTD SASSVHWFRK GLRLHDNPAL LAAVRGARCV RCVYILDPWF 
AASSSVGINR WRFLLQSLED LDTSLRKLNS RLFVVRGQPA DVFPRLFKEW GVTRLTFEYD 
SEPFGKERDA AIMKMAKEAG VEVVTENSHT LYDLDRIIEL NGQKPPLTYK RFQAIISRME 
LPKKPVGLVT SQQMESCRAE IQENHDETYG VPSLEELGFP TEGLGPAVWQ GGETEALARL 
DKHLERKAWV ANYERPRMNA NSLLASPTGL SPYLRFGCLS CRLFYYRLWD LYKKVKRNST 
PPLSLFGQLL WREFFYTAAT NNPRFDRMEG NPICIQIPWD RNPEALAKWA EGKTGFPWID 
AIMTQLRQEG WIHHLARHAV ACFLTRGDLW VSWESGVRVF DELLLDADFS VNAGSWMWLS 
CSAFFQQFFH CYCPVGFGRR TDPSGDYIRR YLPKLKAFPS RYIYEPWNAP ESIQKAAKCI 
IGVDYPRPIV NHAETSRLNI ERMKQIYQQL SRYRGLCLLA SVPSCVEDLS HPVAEPSSSQ 
AGSMSSAGPR PLPSGPASPK RKLEAAEEPP GEELSKRARV AELPTPELPS KDA

Genular Protein ID: 1560361551

Symbol: A0A0D2X7Z3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0D2X7Z3

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 4 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 3 GO 5 Gene3D 3 GeneTree 1 HGNC 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 2 PROSITE 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 614
  • Mass: 68944
  • Checksum: 49E113E9E9D398EA
  • Sequence:
    • MGGVHVAYRG GAGVAGAVWT VMAATVATAA AVAPAPAPGT DSASSVHWFR KGLRLHDNPA 
LLAAVRGARC VRCVYILDPW FAASSSVGIN RWRFLLQSLE DLDTSLRKLN SRLFVVRGQP 
ADVFPRLFKE WGVTRLTFEY DSEPFGKERD AAIMKMAKEA GVEVVTENSH TLYDLDRIIE 
LNGQKPPLTY KRFQAIISRM ELPKKPVGLV TSQQMESCRA EIQENHDETY GVPSLEELGF 
PTEGLGPAVW QGGETEALAR LDKHLERKAW VANYERPRMN ANSLLASPTG LSPYLRFGCL 
SCRLFYYRLW DLYKKVKRNS TPPLSLFGQL LWREFFYTAA TNNPRFDRME GNPICIQIPW 
DRNPEALAKW AEGKTGFPWI DAIMTQLRQE GWIHHLARHA VACFLTRGDL WVSWESGVRV 
FDELLLDADF SVNAGSWMWL SCSAFFQQFF HCYCPVGFGR RTDPSGDYIR RYLPKLKAFP 
SRYIYEPWNA PESIQKAAKC IIGVDYPRPI VNHAETSRLN IERMKQIYQQ LSRYRGLCLL 
ASVPSCVEDL SHPVAEPSSS QAGSMSSAGP RPLPSGPASP KRKLEAAEEP PGEELSKRAR 
VAELPTPELP SKDA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.