Genular: Defining Cellular Identity and Function

Details for: Fbp1

Gene ID: 14121

Symbol: Fbp1

Ensembl ID: ENSMUSG00000069805

Description: fructose bisphosphatase 1

Associated with

Glucose metabolism
(R-MMU-70326)
Metabolism
(R-MMU-1430728)
Metabolism of carbohydrates
(R-MMU-71387)
Amp binding
(GO:0016208)
Carbohydrate metabolic process
(GO:0005975)
Catalytic activity
(GO:0003824)
Cellular response to magnesium ion
(GO:0071286)
Cellular response to xenobiotic stimulus
(GO:0071466)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Dephosphorylation
(GO:0016311)
Extracellular space
(GO:0005615)
Fructose 1,6-bisphosphate 1-phosphatase activity
(GO:0042132)
Fructose 1,6-bisphosphate metabolic process
(GO:0030388)
Fructose 6-phosphate metabolic process
(GO:0006002)
Fructose metabolic process
(GO:0006000)
Gluconeogenesis
(GO:0006094)
Hydrolase activity
(GO:0016787)
Identical protein binding
(GO:0042802)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Monosaccharide binding
(GO:0048029)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of glycolytic process
(GO:0045820)
Negative regulation of ras protein signal transduction
(GO:0046580)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nucleus
(GO:0005634)
Phosphatase activity
(GO:0016791)
Phosphoric ester hydrolase activity
(GO:0042578)
Regulation of gluconeogenesis
(GO:0006111)
Rna polymerase ii-specific dna-binding transcription factor binding
(GO:0061629)
Sucrose biosynthetic process
(GO:0005986)

Other Information

Proteins

Fructose-1,6-bisphosphatase 1

Genular Protein ID: 535896244

Symbol: F16P1_MOUSE

Name: Fructose-1,6-bisphosphatase 1

UniProtKB Accession Codes:

Q9QXD6 P97323 Q3UEH1

Database IDs:

Citations:

PubMed ID: 11250076

Title: Characterization of the mouse liver fructose-1,6-bisphosphatase gene.

PubMed ID: 11250076

DOI: 10.1016/s0378-1119(01)00325-0

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9106734

Title: Various fructose-1,6-bisphosphatase mRNAs in mouse brain, liver, kidney and heart.

PubMed ID: 9106734

DOI: 10.1097/00001756-199702100-00008

PubMed ID: 16497803

Title: Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis.

PubMed ID: 16497803

DOI: 10.1210/en.2005-1498

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18375435

Title: Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function.

PubMed ID: 18375435

DOI: 10.2337/db07-1326

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20719858

Title: Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells.

PubMed ID: 20719858

DOI: 10.1210/en.2009-1185

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 338
Mass: 36912
Checksum: 50AE999F0D517E4F
Sequence:

MANHAPFETD ISTLTRFVME QGRKAQGTGE LTQLLNSLCT AIKAISSAVR QAGIAQLYGI 
AGSTNVTGDQ VKKLDILSND LVINMLKSSY ATCVLVSEEN TNAIIIEPEK RGKYVVCFDP 
LDGSSNIDCL VSIGTIFGIY RKKSTDEPSE KDALQPGRDL VAAGYALYGS ATMLVLAMDC 
GVNCFMLDPS IGEFIMVDRD VKMKKKGNIY SLNEGYAKDF DPAINEYLQR KKFPPDGSAP 
YGARYVGSMV ADIHRTLVYG GIFLYPANKK SPSGKLRLLY ECNPIAYVME KAGGLATTGD 
KDILDIVPTE IHQKAPVVMG SSEDVQEFLE IYRKHKAK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fbp1

Associated with

Other Information

Characterization of the mouse liver fructose-1,6-bisphosphatase gene. PubMed ID: 11250076

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Various fructose-1,6-bisphosphatase mRNAs in mouse brain, liver, kidney and heart. PubMed ID: 9106734

Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis. PubMed ID: 16497803

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function. PubMed ID: 18375435

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Fructose-1,6-bisphosphatase regulates glucose-stimulated insulin secretion of mouse pancreatic beta-cells. PubMed ID: 20719858

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337