Genular: Defining Cellular Identity and Function

Details for: Fcgr1

Gene ID: 14129

Symbol: Fcgr1

Ensembl ID: ENSMUSG00000015947

Description: Fc receptor, IgG, high affinity I

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing-cross presentation
(R-MMU-1236975)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cross-presentation of soluble exogenous antigens (endosomes)
(R-MMU-1236978)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-MMU-2029480)
Fcgr activation
(R-MMU-2029481)
Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Regulation of actin dynamics for phagocytic cup formation
(R-MMU-2029482)
Role of phospholipids in phagocytosis
(R-MMU-2029485)
Antibody-dependent cellular cytotoxicity
(GO:0001788)
Antigen processing and presentation of exogenous antigen
(GO:0019884)
Antigen processing and presentation of exogenous peptide antigen via mhc class i
(GO:0042590)
Cell surface receptor signaling pathway
(GO:0007166)
Defense response to bacterium
(GO:0042742)
External side of plasma membrane
(GO:0009897)
High-affinity igg receptor activity
(GO:0019771)
Igg binding
(GO:0019864)
Igg receptor activity
(GO:0019770)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Leukotriene receptor binding
(GO:0031774)
Membrane
(GO:0016020)
Phagocytosis, engulfment
(GO:0006911)
Phagocytosis, recognition
(GO:0006910)
Plasma membrane
(GO:0005886)
Positive regulation of phagocytosis
(GO:0050766)
Positive regulation of phagocytosis, engulfment
(GO:0060100)
Positive regulation of type iia hypersensitivity
(GO:0001798)
Positive regulation of type iii hypersensitivity
(GO:0001805)
Receptor-mediated endocytosis
(GO:0006898)
Regulation of immune response
(GO:0050776)
Response to bacterium
(GO:0009617)

Other Information

Proteins

High affinity immunoglobulin gamma Fc receptor I

Genular Protein ID: 1702917937

Symbol: FCGR1_MOUSE

Name: High affinity immunoglobulin gamma Fc receptor I

UniProtKB Accession Codes:

P26151

Database IDs:

Citations:

PubMed ID: 2136886

Title: Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

PubMed ID: 2136886

PubMed ID: 1531670

Title: Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene.

PubMed ID: 1531670

PubMed ID: 8478020

Title: Biochemical characterization of murine Fc gamma RI.

PubMed ID: 8478020

PubMed ID: 11911823

Title: FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses.

PubMed ID: 11911823

DOI: 10.1016/s1074-7613(02)00287-x

PubMed ID: 11911824

Title: FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.

PubMed ID: 11911824

DOI: 10.1016/s1074-7613(02)00294-7

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

Sequence Information:

Length: 404
Mass: 44888
Checksum: 1C4F0033842767E7
Sequence:

MILTSFGDDM WLLTTLLLWV PVGGEVVNAT KAVITLQPPW VSIFQKENVT LWCEGPHLPG 
DSSTQWFING TAVQISTPSY SIPEASFQDS GEYRCQIGSS MPSDPVQLQI HNDWLLLQAS 
RRVLTEGEPL ALRCHGWKNK LVYNVVFYRN GKSFQFSSDS EVAILKTNLS HSGIYHCSGT 
GRHRYTSAGV SITVKELFTT PVLRASVSSP FPEGSLVTLN CETNLLLQRP GLQLHFSFYV 
GSKILEYRNT SSEYHIARAE REDAGFYWCE VATEDSSVLK RSPELELQVL GPQSSAPVWF 
HILFYLSVGI MFSLNTVLYV KIHRLQREKK YNLEVPLVSE QGKKANSFQQ VRSDGVYEEV 
TATASQTTPK EAPDGPRSSV GDCGPEQPEP LPPSDSTGAQ TSQS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fcgr1

Associated with

Other Information

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG. PubMed ID: 2136886

Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene. PubMed ID: 1531670

Biochemical characterization of murine Fc gamma RI. PubMed ID: 8478020

FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. PubMed ID: 11911823

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. PubMed ID: 11911824