Genular: Defining Cellular Identity and Function

Details for: Fcna

Gene ID: 14133

Symbol: Fcna

Ensembl ID: ENSMUSG00000026938

Description: ficolin A

Associated with

Complement cascade
(R-MMU-166658)
Creation of c4 and c2 activators
(R-MMU-166786)
Ficolins bind to repetitive carbohydrate structures on the target cell surface
(R-MMU-2855086)
Immune system
(R-MMU-168256)
Initial triggering of complement
(R-MMU-166663)
Innate immune system
(R-MMU-168249)
Lectin pathway of complement activation
(R-MMU-166662)
Neutrophil degranulation
(R-MMU-6798695)
Antigen binding
(GO:0003823)
Carbohydrate binding
(GO:0030246)
Carbohydrate derivative binding
(GO:0097367)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen trimer
(GO:0005581)
Complement activation, lectin pathway
(GO:0001867)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Plasma membrane
(GO:0005886)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

Ficolin-1

Genular Protein ID: 3854921816

Symbol: FCN1_MOUSE

Name: Ficolin-1

UniProtKB Accession Codes:

O70165

Database IDs:

Citations:

PubMed ID: 9535745

Title: Molecular cloning and characterization of mouse ficolin-A.

PubMed ID: 9535745

DOI: 10.1006/bbrc.1998.8344

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17669269

Title: Identification of a functionally relevant signal peptide of mouse ficolin A.

PubMed ID: 17669269

DOI: 10.5483/bmbrep.2007.40.4.532

Sequence Information:

Length: 334
Mass: 36298
Checksum: 9D30C05036AA04B1
Sequence:

MQWPTLWAFS GLLCLCPSQA LGQERGACPD VKVVGLGAQD KVVVIQSCPG FPGPPGPKGE 
PGSPAGRGER GFQGSPGKMG PAGSKGEPGT MGPPGVKGEK GDTGAAPSLG EKELGDTLCQ 
RGPRSCKDLL TRGIFLTGWY TIHLPDCRPL TVLCDMDVDG GGWTVFQRRV DGSIDFFRDW 
DSYKRGFGNL GTEFWLGNDY LHLLTANGNQ ELRVDLQDFQ GKGSYAKYSS FQVSEEQEKY 
KLTLGQFLEG TAGDSLTKHN NMSFTTHDQD NDANSMNCAA LFHGAWWYHN CHQSNLNGRY 
LSGSHESYAD GINWGTGQGH HYSYKVAEMK IRAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.