Genular: Defining Cellular Identity and Function

Details for: Fcnb

Gene ID: 14134

Symbol: Fcnb

Ensembl ID: ENSMUSG00000026835

Description: ficolin B

Associated with

Complement cascade
(R-MMU-166658)
Creation of c4 and c2 activators
(R-MMU-166786)
Ficolins bind to repetitive carbohydrate structures on the target cell surface
(R-MMU-2855086)
Immune system
(R-MMU-168256)
Initial triggering of complement
(R-MMU-166663)
Innate immune system
(R-MMU-168249)
Lectin pathway of complement activation
(R-MMU-166662)
Neutrophil degranulation
(R-MMU-6798695)
Antigen binding
(GO:0003823)
Calcium-dependent protein binding
(GO:0048306)
Carbohydrate binding
(GO:0030246)
Carbohydrate derivative binding
(GO:0097367)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen trimer
(GO:0005581)
Complement activation, lectin pathway
(GO:0001867)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
G protein-coupled receptor binding
(GO:0001664)
Identical protein binding
(GO:0042802)
Immune system process
(GO:0002376)
Innate immune response
(GO:0045087)
Mannan binding
(GO:2001065)
Metal ion binding
(GO:0046872)
Pattern recognition receptor activity
(GO:0038187)
Plasma membrane
(GO:0005886)
Proteoglycan binding
(GO:0043394)
Serine-type endopeptidase complex
(GO:1905370)
Sialic acid binding
(GO:0033691)
Signaling receptor binding
(GO:0005102)

Other Information

Proteins

Ficolin-2

Genular Protein ID: 3522560249

Symbol: FCN2_MOUSE

Name: Ficolin-2

UniProtKB Accession Codes:

O70497 Q3KNL6

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9851834

Title: Oligomeric structure and tissue distribution of ficolins from mouse, pig and human.

PubMed ID: 9851834

DOI: 10.1006/abbi.1998.0957

Sequence Information:

Length: 314
Mass: 33984
Checksum: 6C1467BF0BE96E67
Sequence:

MALGSAALFV LTLTVHAAGT CPELKVLDLE GYKQLTILQG CPGLPGAAGP KGEAGAKGDR 
GESGLPGIPG KEGPTGPKGN QGEKGIRGEK GDSGPSQSCA TGPRTCKELL TQGHFLTGWY 
TIYLPDCRPL TVLCDMDTDG GGWTVFQRRL DGSVDFFRDW TSYKRGFGSQ LGEFWLGNDN 
IHALTTQGTS ELRVDLSDFE GKHDFAKYSS FQIQGEAEKY KLILGNFLGG GAGDSLTPHN 
NRLFSTKDQD NDGSTSSCAM GYHGAWWYSQ CHTSNLNGLY LRGPHKSYAN GVNWKSWRGY 
NYSCKVSEMK VRLI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.