Genular: Defining Cellular Identity and Function

Details for: Fdft1

Gene ID: 14137

Symbol: Fdft1

Ensembl ID: ENSMUSG00000021273

Description: farnesyl diphosphate farnesyl transferase 1

Associated with

Cholesterol biosynthesis
(R-MMU-191273)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Metabolism of steroids
(R-MMU-8957322)
Biosynthetic process
(GO:0009058)
Catalytic activity
(GO:0003824)
Cholesterol biosynthetic process
(GO:0006695)
Cholesterol metabolic process
(GO:0008203)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Farnesyl-diphosphate farnesyltransferase activity
(GO:0004310)
Farnesyl diphosphate metabolic process
(GO:0045338)
Farnesyltranstransferase activity
(GO:0004311)
Isoprenoid biosynthetic process
(GO:0008299)
Lipid biosynthetic process
(GO:0008610)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Metabolic process
(GO:0008152)
Metal ion binding
(GO:0046872)
Squalene synthase activity
(GO:0051996)
Steroid biosynthetic process
(GO:0006694)
Steroid metabolic process
(GO:0008202)
Sterol biosynthetic process
(GO:0016126)
Transferase activity
(GO:0016740)
Transferase activity, transferring alkyl or aryl (other than methyl) groups
(GO:0016765)

Other Information

Proteins

Squalene synthase

Genular Protein ID: 2271477299

Symbol: FDFT_MOUSE

Name: Squalene synthase

UniProtKB Accession Codes:

P53798 Q8BPF5

Database IDs:

Citations:

PubMed ID: 7999794

Title: Molecular cloning and functional expression of a cDNA for mouse squalene synthase.

PubMed ID: 7999794

DOI: 10.1016/0167-4781(94)00178-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10521476

Title: Embryonic lethality and defective neural tube closure in mice lacking squalene synthase.

PubMed ID: 10521476

DOI: 10.1074/jbc.274.43.30843

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 416
Mass: 48154
Checksum: 12C63625DD4FF92B
Sequence:

MEFVKCLGHP EEFYNLLRFR MGGRRNFIPK MDQDSLSSSL KTCYKYLNQT SRSFAAVIQA 
LDGDIRHAIC VFYLVLRALD TVEDDMSISV EKKIPLLCNF HTFLYDPEWR FTESKEKDRQ 
VLEDFPTISL EFRNLAEKYQ TVIDDICHRM GCGMAEFVDK DVTSKQDWDK YCHYVAGLVG 
IGLSRLFSAS EFEDPIVGED IECANSMGLF LQKTNIIRDY LEDQQEGRKF WPQEVWGRYI 
KKLEDFAKPE NVDVAVQCLN ELITNTLQHI PDVLTYLSRL RNQSVFNFCA IPQVMAIATL 
AACYNNQQVF KGVVKIRKGQ AVTLMMDATN MPAVKAIIYQ YIEEIYHRIP NSDPSSSKTK 
QVISKIRTQN LPNCQLISRS HYSPIYLSFI MLLAALSWQY LSTLSQVTED YVQREH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fdft1

Associated with

Other Information

Molecular cloning and functional expression of a cDNA for mouse squalene synthase. PubMed ID: 7999794

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334