Details for: CRYBB1

Gene ID: 1414

Symbol: CRYBB1

Ensembl ID: ENSG00000100122

Description: crystallin beta B1

Associated with

Other Information

Genular Protein ID: 2839523136

Symbol: CRBB1_HUMAN

Name: Beta-crystallin B1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8626774

Title: The sequence of human betaB1-crystallin cDNA allows mass spectrometric detection of betaB1 protein missing portions of its N-terminal extension.

PubMed ID: 8626774

DOI: 10.1074/jbc.271.8.4273

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8575764

Title: Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5.

PubMed ID: 8575764

DOI: 10.1006/geno.1995.9947

PubMed ID: 12360425

Title: A nonsense mutation in CRYBB1 associated with autosomal dominant cataract linked to human chromosome 22q.

PubMed ID: 12360425

DOI: 10.1086/344212

PubMed ID: 15667225

Title: Oligomerization and phase transitions in aqueous solutions of native and truncated human beta B1-crystallin.

PubMed ID: 15667225

DOI: 10.1021/bi048419f

PubMed ID: 16110300

Title: CRYBB1 mutation associated with congenital cataract and microcornea.

PubMed ID: 16110300

PubMed ID: 14573871

Title: Crystal structure of truncated human betaB1-crystallin.

PubMed ID: 14573871

DOI: 10.1110/ps.03265903

PubMed ID: 17460281

Title: Homozygous CRYBB1 deletion mutation underlies autosomal recessive congenital cataract.

PubMed ID: 17460281

DOI: 10.1167/iovs.06-1019

PubMed ID: 21972112

Title: A novel mutation in CRYBB1 associated with congenital cataract-microcornea syndrome: the p.Ser129Arg mutation destabilizes the betaB1/betaA3-crystallin heteromer but not the betaB1-crystallin homomer.

PubMed ID: 21972112

DOI: 10.1002/humu.21436

PubMed ID: 23508780

Title: Whole exome sequencing in dominant cataract identifies a new causative factor, CRYBA2, and a variety of novel alleles in known genes.

PubMed ID: 23508780

DOI: 10.1007/s00439-013-1289-0

PubMed ID: 29386872

Title: Mutations in crystallin genes result in congenital cataract associated with other ocular abnormalities.

PubMed ID: 29386872

PubMed ID: 29914532

Title: Clinical and genetic characteristics of Chinese patients with familial or sporadic pediatric cataract.

PubMed ID: 29914532

DOI: 10.1186/s13023-018-0828-0

PubMed ID: 33243271

Title: The genetic landscape of crystallins in congenital cataract.

PubMed ID: 33243271

DOI: 10.1186/s13023-020-01613-3

Sequence Information:

  • Length: 252
  • Mass: 28023
  • Checksum: 93D81A9C95A86F7F
  • Sequence:
  • MSQAAKASAS ATVAVNPGPD TKGKGAPPAG TSPSPGTTLA PTTVPITSAK AAELPPGNYR 
    LVVFELENFQ GRRAEFSGEC SNLADRGFDR VRSIIVSAGP WVAFEQSNFR GEMFILEKGE 
    YPRWNTWSSS YRSDRLMSFR PIKMDAQEHK ISLFEGANFK GNTIEIQGDD APSLWVYGFS 
    DRVGSVKVSS GTWVGYQYPG YRGYQYLLEP GDFRHWNEWG AFQPQMQSLR RLRDKQWHLE 
    GSFPVLATEP PK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.