Details for: CRYBB2

Gene ID: 1415

Symbol: CRYBB2

Ensembl ID: ENSG00000244752

Description: crystallin beta B2

Associated with

Other Information

Genular Protein ID: 3093944648

Symbol: CRBB2_HUMAN

Name: Beta-crystallin B2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8224918

Title: Sequence of the human lens beta B2-crystallin-encoding cDNA.

PubMed ID: 8224918

DOI: 10.1016/0378-1119(93)90655-m

PubMed ID: 9158139

Title: Autosomal dominant cerulean cataract is associated with a chain termination mutation in the human beta-crystallin gene CRYBB2.

PubMed ID: 9158139

DOI: 10.1093/hmg/6.5.665

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8443605

Title: Amino acid sequence of human lens beta B2-crystallin.

PubMed ID: 8443605

DOI: 10.1002/pro.5560020217

PubMed ID: 8999933

Title: Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.

PubMed ID: 8999933

DOI: 10.1074/jbc.272.4.2268

PubMed ID: 1521468

Title: Two-dimensional gel electrophoretic analysis of human lens proteins.

PubMed ID: 1521468

DOI: 10.3109/02713689209000740

PubMed ID: 8175657

Title: Post-translational modifications of water-soluble human lens crystallins from young adults.

PubMed ID: 8175657

DOI: 10.1016/s0021-9258(18)99902-3

PubMed ID: 10930324

Title: The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage.

PubMed ID: 10930324

DOI: 10.1006/exer.2000.0868

PubMed ID: 10634616

Title: Genetic heterogeneity of the Coppock-like cataract: a mutation in CRYBB2 on chromosome 22q11.2.

PubMed ID: 10634616

PubMed ID: 28839118

Title: High-Throughput Genetic Screening of 51 Pediatric Cataract Genes Identifies Causative Mutations in Inherited Pediatric Cataract in South Eastern Australia.

PubMed ID: 28839118

DOI: 10.1534/g3.117.300109

PubMed ID: 29386872

Title: Mutations in crystallin genes result in congenital cataract associated with other ocular abnormalities.

PubMed ID: 29386872

PubMed ID: 29259299

Title: Two novel mutations identified in ADCC families impair crystallin protein distribution and induce apoptosis in human lens epithelial cells.

PubMed ID: 29259299

DOI: 10.1038/s41598-017-18222-z

PubMed ID: 31523120

Title: Mutation screening of crystallin genes in Chinese families with congenital cataracts.

PubMed ID: 31523120

PubMed ID: 17327390

Title: Mutation of interfaces in domain-swapped human betaB2-crystallin.

PubMed ID: 17327390

DOI: 10.1110/ps.062659107

Sequence Information:

  • Length: 205
  • Mass: 23380
  • Checksum: FD95C354724A67D0
  • Sequence:
  • MASDHQTQAG KPQSLNPKII IFEQENFQGH SHELNGPCPN LKETGVEKAG SVLVQAGPWV 
    GYEQANCKGE QFVFEKGEYP RWDSWTSSRR TDSLSSLRPI KVDSQEHKII LYENPNFTGK 
    KMEIIDDDVP SFHAHGYQEK VSSVRVQSGT WVGYQYPGYR GLQYLLEKGD YKDSSDFGAP 
    HPQVQSVRRI RDMQWHQRGA FHPSN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.