Details for: Fech

Gene ID: 14151

Symbol: Fech

Ensembl ID: ENSMUSG00000024588

Description: ferrochelatase

Associated with

Other Information

Genular Protein ID: 1495957217

Symbol: HEMH_MOUSE

Name: Ferrochelatase, mitochondrial

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2246229

Title: Molecular cloning, sequencing, and expression of mouse ferrochelatase.

PubMed ID: 2246229

DOI: 10.1016/s0021-9258(17)45378-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 1704134

Title: Cloning of murine ferrochelatase.

PubMed ID: 1704134

DOI: 10.1073/pnas.88.3.849

PubMed ID: 8276824

Title: Mammalian ferrochelatase. Expression and characterization of normal and two human protoporphyric ferrochelatases.

PubMed ID: 8276824

DOI: 10.1016/s0021-9258(17)42362-3

PubMed ID: 16452087

Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

PubMed ID: 16452087

DOI: 10.1074/mcp.t500041-mcp200

PubMed ID: 20427704

Title: Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.

PubMed ID: 20427704

DOI: 10.1182/blood-2009-12-259614

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

PubMed ID: 27599036

Title: A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase.

PubMed ID: 27599036

DOI: 10.1021/acs.biochem.6b00756

PubMed ID: 30765471

Title: Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.

PubMed ID: 30765471

DOI: 10.3324/haematol.2018.214320

PubMed ID: 8325637

Title: Ferrochelatase structural mutant (Fechm1Pas) in the house mouse.

PubMed ID: 8325637

DOI: 10.1006/geno.1993.1242

Sequence Information:

  • Length: 422
  • Mass: 47422
  • Checksum: 037EE8041930C2C9
  • Sequence:
  • MLSASANMAA ALRAAGALLR EPLVHGSSRA CQPWRCQSGA AVAATTEKVH HAKTTKPQAQ 
    PERRKPKTGI LMLNMGGPET LGEVQDFLQR LFLDRDLMTL PIQNKLAPFI AKRRTPKIQE 
    QYRRIGGGSP IKMWTSKQGE GMVKLLDELS PATAPHKYYI GFRYVHPLTE EAIEEMERDG 
    LERAIAFTQY PQYSCSTTGS SLNAIYRYYN EVGQKPTMKW STIDRWPTHP LLIQCFADHI 
    LKELNHFPEE KRSEVVILFS AHSLPMSVVN RGDPYPQEVG ATVHKVMEKL GYPNPYRLVW 
    QSKVGPVPWL GPQTDEAIKG LCERGRKNIL LVPIAFTSDH IETLYELDIE YSQVLAQKCG 
    AENIRRAESL NGNPLFSKAL ADLVHSHIQS NKLCSTQLSL NCPLCVNPVC RKTKSFFTSQ 
    QL

Genular Protein ID: 3002388686

Symbol: Q4QRK2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 399
  • Mass: 44756
  • Checksum: A3FCF327E9232ED1
  • Sequence:
  • AFPGLAGAPP QRIPGRPGNA FGQRQHGCGP AGCGRSAPRA AKPKTGILML NMGGPETLGE 
    VQDFLQRLFL DRDLMTLPIQ NKLAPFIAKR RTPKIQEQYR RIGGGSPIKM WTSKQGEGMV 
    KLLDELSPAT APHKYYIGFR YVHPLTEEAI EEMERDGLER AIAFTQYPQY SCSTTGSSLN 
    AIYRYYNEVG QKPTMKWSTI DRWPTHPLLI QCFADHILKE LNHFPEEKRS EVVILFSARS 
    LPMSVVNRGD PYPQEVGATV HKVMEKLGYP NPYRLVWQSK VGPVPWLGPQ TDEAIKGLCE 
    RGRKNILLVP IAFTSDHIET LYELDIEYSQ VLAQKRGAEN IRRAESLNGN PLFSKALADL 
    VHSHIQSNKL CSTQLSLNCP LCVNPVCRKT KSFFTSQQL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.