Fen1 | ENSMUSG00000024742 | NCBI 14156

Details for: Fen1

Gene ID: 14156

Symbol: Fen1

Ensembl ID: ENSMUSG00000024742

Description: flap structure specific endonuclease 1

Associated with

Base excision repair
(R-MMU-73884)
Cell cycle
(R-MMU-1640170)
Cell cycle, mitotic
(R-MMU-69278)
Chromosome maintenance
(R-MMU-73886)
Dna double-strand break repair
(R-MMU-5693532)
Dna strand elongation
(R-MMU-69190)
Extension of telomeres
(R-MMU-180786)
Hdr through mmej (alt-nhej)
(R-MMU-5685939)
Homology directed repair
(R-MMU-5693538)
Lagging strand synthesis
(R-MMU-69186)
Pcna-dependent long patch base excision repair
(R-MMU-5651801)
Polb-dependent long patch base excision repair
(R-MMU-110362)
Processive synthesis on the c-strand of the telomere
(R-MMU-174414)
Processive synthesis on the lagging strand
(R-MMU-69183)
Removal of the flap intermediate
(R-MMU-69166)
Removal of the flap intermediate from the c-strand
(R-MMU-174437)
Resolution of abasic sites (ap sites)
(R-MMU-73933)
Resolution of ap sites via the multiple-nucleotide patch replacement pathway
(R-MMU-110373)
S phase
(R-MMU-69242)
Synthesis of dna
(R-MMU-69239)
Telomere c-strand (lagging strand) synthesis
(R-MMU-174417)
Telomere maintenance
(R-MMU-157579)
5'-3' exonuclease activity
(GO:0008409)
5'-flap endonuclease activity
(GO:0017108)
Catalytic activity
(GO:0003824)
Chromosome, telomeric region
(GO:0000781)
Dna binding
(GO:0003677)
Dna damage response
(GO:0006974)
Dna repair
(GO:0006281)
Dna replication
(GO:0006260)
Dna replication, removal of rna primer
(GO:0043137)
Endonuclease activity
(GO:0004519)
Exonuclease activity
(GO:0004527)
Flap endonuclease activity
(GO:0048256)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on ester bonds
(GO:0016788)
Magnesium ion binding
(GO:0000287)
Manganese ion binding
(GO:0030145)
Memory
(GO:0007613)
Metal ion binding
(GO:0046872)
Mitochondrion
(GO:0005739)
Nuclease activity
(GO:0004518)
Nucleic acid metabolic process
(GO:0090304)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of sister chromatid cohesion
(GO:0045876)
Protein-containing complex
(GO:0032991)
Rna-dna hybrid ribonuclease activity
(GO:0004523)

Other Information

Proteins

Q91Z50_MOUSE
Q8C952_MOUSE

Genular Protein ID: 3636054852

Symbol: Q91Z50_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q91Z50

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15967598

Title: Structure and transcription promoter activity of mouse flap endonuclease 1 gene: alternative splicing and bidirectional promoter.

PubMed ID: 15967598

DOI: 10.1016/j.gene.2005.05.009

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

Sequence Information:

Length: 380
Mass: 42623
Checksum: 1BE903288B46520D
Sequence:

MGIHGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET 
TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ LQQAQEAGME 
EEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALAKAG KVYAAATEDM 
DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RVLQELGLNQ EQFVDLCILL GSDYCESIRG 
IGPKRAVDLI QKHKSIEEIV RRLDPSKYPV PENWLHKEAQ QLFLEPEVLD PESVELKWSE 
PNEEELVKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP 
KGPAKKKAKT GGAGKFRRGK

Genular Protein ID: 1806414929

Symbol: Q8C952_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8C952

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 380
Mass: 42589
Checksum: E94B8B2718896B6E
Sequence:

MGIHGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET 
TSHLMGMFYR TIRMMENGIK PVYVLDGKPP QLKSGELAKR SERRAEAEKQ LQQAQEAGME 
EEVEKFTKRL VKVTKQHNDE CKHLLSLMGI PYLDAPSEAE ASCAALAKAG KVYAAATEDM 
DCLTFGSPVL MRHLTASEAK KLPIQEFHLS RVLQELGLNQ EQFVDLCILL GSDYCESIRG 
IGPKRAVDLI QKHKSIEEIV RRLDPSKYPV PENWLHKEAQ QLFLEPEVLD PESVELKWSE 
PNEEELVKFM CGEKQFSEER IRSGVKRLSK SRQGSTQGRL DDFFKVTGSL SSAKRKEPEP 
KGPAKKKAKT GGAGKFRRGK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fen1

Associated with

Other Information

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Structure and transcription promoter activity of mouse flap endonuclease 1 gene: alternative splicing and bidirectional promoter. PubMed ID: 15967598

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073

Database document:

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 15489334

PubMed ID: 15967598

PubMed ID: 16141073

PubMed ID: 19468303

PubMed ID: 21183079

PubMed ID: 23806337

PubMed ID: 10349636

PubMed ID: 11042159

PubMed ID: 11076861

PubMed ID: 11217851

PubMed ID: 12466851

PubMed ID: 16141073