Details for: Fer

Gene ID: 14158

Symbol: Fer

Ensembl ID: ENSMUSG00000000127

Description: FER tyrosine kinase

Associated with

Other Information

Genular Protein ID: 2372113945

Symbol: FER_MOUSE

Name: Tyrosine-protein kinase Fer

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2294399

Title: A murine fer testis-specific transcript (ferT) encodes a truncated Fer protein.

PubMed ID: 2294399

DOI: 10.1128/mcb.10.1.146-153.1990

PubMed ID: 11006284

Title: The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase.

PubMed ID: 11006284

DOI: 10.1074/jbc.m006665200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 7623846

Title: The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.

PubMed ID: 7623846

DOI: 10.1128/mcb.15.8.4553

PubMed ID: 9742951

Title: Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases.

PubMed ID: 9742951

DOI: 10.1016/s0014-5793(98)01003-5

PubMed ID: 10074905

Title: Cell cycle-dependent nuclear accumulation of the p94fer tyrosine kinase is regulated by its NH2 terminus and is affected by kinase domain integrity and ATP binding.

PubMed ID: 10074905

PubMed ID: 10391941

Title: Disruption of coiled-coil domains in Fer protein-tyrosine kinase abolishes trimerization but not kinase activation.

PubMed ID: 10391941

DOI: 10.1074/jbc.274.28.19934

PubMed ID: 10878010

Title: FER kinase activation of Stat3 is determined by the N-terminal sequence.

PubMed ID: 10878010

DOI: 10.1074/jbc.m003402200

PubMed ID: 11339827

Title: Subcellular localization analysis of the closely related Fps/Fes and Fer protein-tyrosine kinases suggests a distinct role for Fps/Fes in vesicular trafficking.

PubMed ID: 11339827

DOI: 10.1006/excr.2001.5217

PubMed ID: 11134346

Title: Mice devoid of fer protein-tyrosine kinase activity are viable and fertile but display reduced cortactin phosphorylation.

PubMed ID: 11134346

DOI: 10.1128/mcb.21.2.603-613.2001

PubMed ID: 12200133

Title: Direct binding of plectin to Fer kinase and negative regulation of its catalytic activity.

PubMed ID: 12200133

DOI: 10.1016/s0006-291x(02)02007-7

PubMed ID: 11994443

Title: Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin.

PubMed ID: 11994443

DOI: 10.4049/jimmunol.168.10.4930

PubMed ID: 12901971

Title: Fps/Fes and Fer protein-tyrosine kinases play redundant roles in regulating hematopoiesis.

PubMed ID: 12901971

DOI: 10.1016/s0301-472x(03)00107-3

PubMed ID: 12738762

Title: Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells.

PubMed ID: 12738762

DOI: 10.1210/me.2002-0328

PubMed ID: 15226396

Title: Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer.

PubMed ID: 15226396

DOI: 10.1242/jcs.01174

PubMed ID: 15467733

Title: TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3.

PubMed ID: 15467733

DOI: 10.1038/sj.onc.1208149

PubMed ID: 16176974

Title: Phosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength.

PubMed ID: 16176974

DOI: 10.1091/mbc.e05-05-0410

PubMed ID: 16731527

Title: Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.

PubMed ID: 16731527

DOI: 10.1074/jbc.m604252200

PubMed ID: 16732323

Title: Downregulation of Fer induces PP1 activation and cell-cycle arrest in malignant cells.

PubMed ID: 16732323

DOI: 10.1038/sj.onc.1209695

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

DOI: 10.4049/jimmunol.179.9.5864

PubMed ID: 17606629

Title: Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion.

PubMed ID: 17606629

DOI: 10.1128/mcb.01744-06

PubMed ID: 19159681

Title: Hsp90 and a tyrosine embedded in the Hsp90 recognition loop are required for the Fer tyrosine kinase activity.

PubMed ID: 19159681

DOI: 10.1016/j.cellsig.2008.12.011

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.m800451-mcp200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20133938

Title: Neuropilin 1 directly interacts with Fer kinase to mediate semaphorin 3A-induced death of cortical neurons.

PubMed ID: 20133938

DOI: 10.1074/jbc.m109.080689

Sequence Information:

  • Length: 823
  • Mass: 94579
  • Checksum: F4C22E1E63721663
  • Sequence:
  • MGFGSDLKNS QEAVLKLQDW ELRLLETVKK FMALRIKSDK EYAYTLQNLC NQVDKESTVQ 
    VNYVSNVSKS WLLMIQQTEQ LSRIMKTHAE DLNSGPLHRL TMMIKDKQQV KKSYVGIHQQ 
    IEAEMIKVTK TELEKLKSSY RQLIKEMNSA KEKYKEALAK GKETEKAKER YDKATMKLHM 
    LHNQYVLALK GAQLHQSQYY DTTLPLLLDS VQKMQEEMIK ALKGIFDDYS QITSLVTEEI 
    VNVHKEIQMS VEQIDPSTEY NNFIDVHRTT AAKEQEIEFD TSLLEENENL QANEIMWNNL 
    TADSLQVMLK TLAEELTQTQ QMLLHKEAAV LELEKRIEES FETCEKKSDI VLLLGQKQAL 
    EELKQSVQQL RCTEAKCAAQ KALLEQKVQE NDGKEPPPVV NYEEDARSVT SMERKERLSK 
    FESIRHSIAG IIKSPKSVLG SSTQVCDVIS VGERPLAEHD WYHGAIPRIE AQELLKQQGD 
    FLVRESHGKP GEYVLSVYSD GQRRHFIIQF VDNLYRFEGT GFSNIPQLID HHFNTKQVIT 
    KKSGVVLLNP IPKDKKWVLN HEDVSLGELL GKGNFGEVYK GTLKDKTPVA IKTCKEDLPQ 
    ELKIKFLQEA KILKQYDHPN IVKLIGVCTQ RQPVYIIMEL VPGGDFLTFL RKRKDELKLK 
    QLVRFSLDVA AGMLYLESKN CIHRDLAARN CLVGENNTLK ISDFGMSRQE DGGVYSSSGL 
    KQIPIKWTAP EALNYGRYSS ESDVWSFGIL LWETFSLGVC PYPGMTNQQA REQVERGYRM 
    SAPQNCPEEV FTIMMKCWDY KPENRPKFND LHKELTVIKK MIT

Genular Protein ID: 356154783

Symbol: Q3TME9_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 389
  • Mass: 45072
  • Checksum: B9E29A0E07A6361C
  • Sequence:
  • MGFGSDLKNS QEAVLKLQDW ELRLLETVKK FMALRIKSDK EYAYTLQNLC NQVDKESTVQ 
    VNYVSNVSKS WLLMIQQTEQ LSRIMKTHAE DLNSGPLHRL TMMIKDKQQV KKSYVGIHQQ 
    IEAEMIKVTK TELEKLKSSY RQLIKEMNSA KEKYKEALAK GKETEKAKER YDKATMKLHM 
    LHNQYVLALK GAQLHQSQYY DTTLPLLLDS VQKMQEEMIK ALKGIFDDYS QITSLVTEEI 
    VNVHKEIQMS VEQIDPSTEY NNFIDVHRTT AAKEQEIEFD TSLLEENENL QANEIMWNNL 
    TADSLQVMLK TLAEELTQTQ QMLLHKEAAV LELEKRIEES FETCEKKSDI VLLLGQKQAL 
    EELKQSVQQL RCTEAKCAAQ KALLEQKVQ

Genular Protein ID: 159935795

Symbol: Q3TZJ5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 17947660

Title: Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.

PubMed ID: 17947660

PubMed ID: 19131326

Title: Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

PubMed ID: 19131326

DOI: 10.1074/mcp.M800451-MCP200

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

  • Length: 645
  • Mass: 74020
  • Checksum: 8F90B10A4F66BB9F
  • Sequence:
  • MGFGSDLKNS QEAVLKLQDW ELRLLETVKK FMALRIKSDK EYAYTLQNLC NQVDKESTVQ 
    VNYVSNVSKS WLLMIQQTEQ LSRIMKTHAE DLNSGPLHRL TMMIKDKQQV KKSYVGIHQQ 
    IEAEMIKVTK TELEKLKSSY RQLIKEMNSA KEKYKEALAK GKETEKAKER YDKATMKLHM 
    LHNQYVLALK GAQLHQSQYY DTTLPLLLDS VQKMQEEMIK ALKGIFDDYS QITSLVTEEI 
    VNVHKEIQMS VEQIDPSTEY NNFIDVHRTT AAKEQEIEFD TSLLEENENL QANEIMWNNL 
    TADSLQVMLK TLAEELTQTQ QMLLHKEAAV LELEKRIEES FETCEKKSDI VLLLGQKQAL 
    EELKQSVQQL RCTEAKCAAQ KALLEQKVQE NDGKEPPPVV NYEEDARSVT SMERKERLSK 
    FESIRHSIAG IIKSPKSVLG SSTVCDVISV GERPLAEHDW YHGAIPRIEA QELLKQQGDF 
    LVRESHGKPG EYVLSVYSDG QRRHFIIQFV DNLYRFEGTG FSNIPQLIDH HFNTKQVITK 
    KSGVVLLNPI PKDKKWVLNH EDVSLGELLG KGNFGEVYKG TLKDKTPVAI KTCKEDLPQE 
    LKIKFLQEAK ILKQYDHPNI VKLIGVCTQR QPVYIIMELV PGNAI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.