Details for: Lgr5
Associated with
Other Information
Genular Protein ID: 2201331732
Symbol: LGR5_MOUSE
Name: Leucine-rich repeat-containing G-protein coupled receptor 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9920770
Title: Identification of a novel seven-transmembrane receptor with homology to glycoprotein receptors and its expression in the adult and developing mouse.
PubMed ID: 9920770
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15509778
Title: Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension.
PubMed ID: 15509778
PubMed ID: 17934449
Title: Identification of stem cells in small intestine and colon by marker gene Lgr5.
PubMed ID: 17934449
DOI: 10.1038/nature06196
PubMed ID: 18849992
Title: Lgr5 marks cycling, yet long-lived, hair follicle stem cells.
PubMed ID: 18849992
DOI: 10.1038/ng.239
PubMed ID: 21727895
Title: Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
PubMed ID: 21727895
DOI: 10.1038/nature10337
PubMed ID: 22510880
Title: Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.
PubMed ID: 22510880
PubMed ID: 29769720
Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
PubMed ID: 29769720
Sequence Information:
- Length: 907
- Mass: 99666
- Checksum: 5E202CB356DB12CF
- Sequence:
MDTSCVHMLL SLLALLQLVA AGSSPGPDAI PRGCPSHCHC ELDGRMLLRV DCSDLGLSEL PSNLSVFTSY LDLSMNNISQ LPASLLHRLC FLEELRLAGN ALTHIPKGAF TGLHSLKVLM LQNNQLRQVP EEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTDVPVQ AFRSLSALQA MTLALNKIHH IADYAFGNLS SLVVLHLHNN RIHSLGKKCF DGLHSLETLD LNYNNLDEFP TAIKTLSNLK ELGFHSNNIR SIPERAFVGN PSLITIHFYD NPIQFVGVSA FQHLPELRTL TLNGASHITE FPHLTGTATL ESLTLTGAKI SSLPQAVCDQ LPNLQVLDLS YNLLEDLPSL SGCQKLQKID LRHNEIYEIK GSTFQQLFNL RSLNLAWNKI AIIHPNAFST LPSLIKLDLS SNLLSSFPVT GLHGLTHLKL TGNRALQSLI PSANFPELKI IEMPSAYQCC AFGGCENVYK ISNQWNKDDG NSVDDLHKKD AGLFQVQDER DLEDFLLDFE EDLKALHSVQ CSPSPGPFKP CEHLFGSWLI RIGVWTTAVL ALSCNALVAL TVFRTPLYIS SIKLLIGVIA VVDILMGVSS AVLAAVDAFT FGRFAQHGAW WEDGIGCQIV GFLSIFASES SIFLLTLAAL ERGFSVKCSS KFEVKAPLFS LRAIVLLCVL LALTIATIPL LGGSKYNASP LCLPLPFGEP STTGYMVALV LLNSLCFLIM TIAYTKLYCS LEKGELENLW DCSMVKHIAL LLFANCILYC PVAFLSFSSL LNLTFISPDV IKFILLVIVP LPSCLNPLLY IVFNPHFKED MGSLGKHTRF WMRSKHASLL SINSDDVEKR SCESTQALVS FTHASIAYDL PSTSGASPAY PMTESCHLSS VAFVPCL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.