Genular: Defining Cellular Identity and Function

Details for: Fgf1

Gene ID: 14164

Symbol: Fgf1

Ensembl ID: ENSMUSG00000036585

Description: fibroblast growth factor 1

Associated with

Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Downstream signaling of activated fgfr3
(R-MMU-5654708)
Downstream signaling of activated fgfr4
(R-MMU-5654716)
Fgfr1 ligand binding and activation
(R-MMU-190242)
Fgfr1b ligand binding and activation
(R-MMU-190370)
Fgfr1c ligand binding and activation
(R-MMU-190373)
Fgfr2 ligand binding and activation
(R-MMU-190241)
Fgfr2b ligand binding and activation
(R-MMU-190377)
Fgfr2c ligand binding and activation
(R-MMU-190375)
Fgfr3 ligand binding and activation
(R-MMU-190239)
Fgfr3b ligand binding and activation
(R-MMU-190371)
Fgfr3c ligand binding and activation
(R-MMU-190372)
Fgfr4 ligand binding and activation
(R-MMU-190322)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Frs-mediated fgfr3 signaling
(R-MMU-5654706)
Frs-mediated fgfr4 signaling
(R-MMU-5654712)
Igf1r signaling cascade
(R-MMU-2428924)
Insulin receptor signalling cascade
(R-MMU-74751)
Intracellular signaling by second messengers
(R-MMU-9006925)
Irs-mediated signalling
(R-MMU-112399)
Irs-related events triggered by igf1r
(R-MMU-2428928)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Negative regulation of fgfr1 signaling
(R-MMU-5654726)
Negative regulation of fgfr2 signaling
(R-MMU-5654727)
Negative regulation of fgfr3 signaling
(R-MMU-5654732)
Negative regulation of fgfr4 signaling
(R-MMU-5654733)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Phospholipase c-mediated cascade: fgfr1
(R-MMU-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-MMU-5654221)
Phospholipase c-mediated cascade; fgfr3
(R-MMU-5654227)
Phospholipase c-mediated cascade; fgfr4
(R-MMU-5654228)
Pi-3k cascade:fgfr1
(R-MMU-5654689)
Pi-3k cascade:fgfr2
(R-MMU-5654695)
Pi-3k cascade:fgfr3
(R-MMU-5654710)
Pi-3k cascade:fgfr4
(R-MMU-5654720)
Pi3k cascade
(R-MMU-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Raf/map kinase cascade
(R-MMU-5673001)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Shc-mediated cascade:fgfr3
(R-MMU-5654704)
Shc-mediated cascade:fgfr4
(R-MMU-5654719)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-MMU-2404192)
Signal transduction
(R-MMU-162582)
Activation of protein kinase b activity
(GO:0032148)
Angiogenesis
(GO:0001525)
Animal organ morphogenesis
(GO:0009887)
Branch elongation involved in ureteric bud branching
(GO:0060681)
Cardiac muscle cell proliferation
(GO:0060038)
Cell differentiation
(GO:0030154)
Cellular response to heat
(GO:0034605)
Epithelial cell proliferation
(GO:0050673)
Extracellular region
(GO:0005576)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Growth factor activity
(GO:0008083)
Heparin binding
(GO:0008201)
Hsp70 protein binding
(GO:0030544)
Integrin binding
(GO:0005178)
Lung development
(GO:0030324)
Mesonephric epithelium development
(GO:0072163)
Multicellular organism development
(GO:0007275)
Organ induction
(GO:0001759)
Positive regulation of angiogenesis
(GO:0045766)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of cholesterol biosynthetic process
(GO:0045542)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of hepatocyte proliferation
(GO:2000347)
Positive regulation of intracellular signal transduction
(GO:1902533)
Positive regulation of map kinase activity
(GO:0043406)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of sprouting angiogenesis
(GO:1903672)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of endothelial cell chemotaxis to fibroblast growth factor
(GO:2000544)
Regulation of endothelial tube morphogenesis
(GO:1901509)
S100 protein binding
(GO:0044548)
Vasculogenesis involved in coronary vascular morphogenesis
(GO:0060979)
Wound healing
(GO:0042060)

Other Information

Proteins

Fibroblast growth factor 1

Genular Protein ID: 4239105394

Symbol: FGF1_MOUSE

Name: Fibroblast growth factor 1

UniProtKB Accession Codes:

P61148 P10935

Database IDs:

Citations:

PubMed ID: 2318343

Title: Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis.

PubMed ID: 2318343

DOI: 10.1016/0012-1606(90)90211-z

PubMed ID: 8972905

Title: Cloning and characterization of the mouse Fgf-1 gene.

PubMed ID: 8972905

DOI: 10.1016/s0378-1119(96)00365-4

PubMed ID: 8939980

Title: Characterization of the 1B promoter of fibroblast growth factor 1 and its expression in the adult and developing mouse brain.

PubMed ID: 8939980

DOI: 10.1074/jbc.271.47.30263

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 155
Mass: 17418
Checksum: 8880E4FF0FBA4161
Sequence:

MAEGEITTFA ALTERFNLPL GNYKKPKLLY CSNGGHFLRI LPDGTVDGTR DRSDQHIQLQ 
LSAESAGEVY IKGTETGQYL AMDTEGLLYG SQTPNEECLF LERLEENHYN TYTSKKHAEK 
NWFVGLKKNG SCKRGPRTHY GQKAILFLPL PVSSD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgf1

Associated with

Other Information

Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. PubMed ID: 2318343

Cloning and characterization of the mouse Fgf-1 gene. PubMed ID: 8972905

Characterization of the 1B promoter of fibroblast growth factor 1 and its expression in the adult and developing mouse brain. PubMed ID: 8939980