Genular: Defining Cellular Identity and Function

Details for: Fgf10

Gene ID: 14165

Symbol: Fgf10

Ensembl ID: ENSMUSG00000021732

Description: fibroblast growth factor 10

Associated with

Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Fgfr1 ligand binding and activation
(R-MMU-190242)
Fgfr1b ligand binding and activation
(R-MMU-190370)
Fgfr2 ligand binding and activation
(R-MMU-190241)
Fgfr2b ligand binding and activation
(R-MMU-190377)
Fgfrl1 modulation of fgfr1 signaling
(R-MMU-5658623)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Igf1r signaling cascade
(R-MMU-2428924)
Insulin receptor signalling cascade
(R-MMU-74751)
Intracellular signaling by second messengers
(R-MMU-9006925)
Irs-mediated signalling
(R-MMU-112399)
Irs-related events triggered by igf1r
(R-MMU-2428928)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Negative regulation of fgfr1 signaling
(R-MMU-5654726)
Negative regulation of fgfr2 signaling
(R-MMU-5654727)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Phospholipase c-mediated cascade: fgfr1
(R-MMU-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-MMU-5654221)
Pi-3k cascade:fgfr1
(R-MMU-5654689)
Pi-3k cascade:fgfr2
(R-MMU-5654695)
Pi3k cascade
(R-MMU-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Raf/map kinase cascade
(R-MMU-5673001)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-MMU-2404192)
Signal transduction
(R-MMU-162582)
Actin cytoskeleton organization
(GO:0030036)
Animal organ morphogenesis
(GO:0009887)
Blood vessel remodeling
(GO:0001974)
Cell-cell signaling
(GO:0007267)
Cell differentiation
(GO:0030154)
Cell population proliferation
(GO:0008283)
Chemoattractant activity
(GO:0042056)
Chemotaxis
(GO:0006935)
Determination of left/right symmetry
(GO:0007368)
Embryonic camera-type eye development
(GO:0031076)
Embryonic genitalia morphogenesis
(GO:0030538)
Embryonic pattern specification
(GO:0009880)
Endothelial cell proliferation
(GO:0001935)
Epidermis development
(GO:0008544)
Epithelial cell differentiation
(GO:0030855)
Establishment of mitotic spindle orientation
(GO:0000132)
Fibroblast growth factor receptor binding
(GO:0005104)
Growth factor activity
(GO:0008083)
Hair follicle morphogenesis
(GO:0031069)
Heparin binding
(GO:0008201)
Inner ear morphogenesis
(GO:0042472)
Lacrimal gland development
(GO:0032808)
Limb morphogenesis
(GO:0035108)
Lung development
(GO:0030324)
Metanephros morphogenesis
(GO:0003338)
Mitotic cell cycle
(GO:0000278)
Negative regulation of epithelial cell differentiation
(GO:0030857)
Organ growth
(GO:0035265)
Organ induction
(GO:0001759)
Otic vesicle formation
(GO:0030916)
Pancreas development
(GO:0031016)
Pituitary gland development
(GO:0021983)
Positive regulation of atp-dependent activity
(GO:0032781)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of epithelial cell migration
(GO:0010634)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of keratinocyte proliferation
(GO:0010838)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of vascular endothelial growth factor receptor signaling pathway
(GO:0030949)
Positive regulation of wnt signaling pathway
(GO:0030177)
Protein binding
(GO:0005515)
Protein localization to cell surface
(GO:0034394)
Regulation of activin receptor signaling pathway
(GO:0032925)
Regulation of gene expression
(GO:0010468)
Regulation of smoothened signaling pathway
(GO:0008589)
Salivary gland development
(GO:0007431)
Salivary gland morphogenesis
(GO:0007435)
Somatic stem cell population maintenance
(GO:0035019)
Thyroid gland development
(GO:0030878)
Type 2 fibroblast growth factor receptor binding
(GO:0005111)
Wnt signaling pathway
(GO:0016055)
Wound healing
(GO:0042060)

Other Information

Proteins

Fibroblast growth factor 10

Genular Protein ID: 2048522205

Symbol: FGF10_MOUSE

Name: Fibroblast growth factor 10

UniProtKB Accession Codes:

O35565 Q543V5

Database IDs:

Citations:

PubMed ID: 9332392

Title: Cloning of mouse FGF10 and up-regulation of its gene expression during wound healing.

PubMed ID: 9332392

DOI: 10.1016/s0378-1119(97)00187-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 209
Mass: 23597
Checksum: 7FD22227BF4943CC
Sequence:

MWKWILTHCA SAFPHLPGCC CCFLLLFLVS SFPVTCQALG QDMVSQEATN CSSSSSSFSS 
PSSAGRHVRS YNHLQGDVRW RRLFSFTKYF LTIEKNGKVS GTKNEDCPYS VLEITSVEIG 
VVAVKAINSN YYLAMNKKGK LYGSKEFNND CKLKERIEEN GYNTYASFNW QHNGRQMYVA 
LNGKGAPRRG QKTRRKNTSA HFLPMTIQT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.