Genular: Defining Cellular Identity and Function

Details for: Fgf15

Gene ID: 14170

Symbol: Fgf15

Ensembl ID: ENSMUSG00000031073

Description: fibroblast growth factor 15

Associated with

Betaklotho-mediated ligand binding
(R-MMU-1307965)
Downstream signaling of activated fgfr4
(R-MMU-5654716)
Fgfr4 ligand binding and activation
(R-MMU-190322)
Frs-mediated fgfr4 signaling
(R-MMU-5654712)
Igf1r signaling cascade
(R-MMU-2428924)
Insulin receptor signalling cascade
(R-MMU-74751)
Intracellular signaling by second messengers
(R-MMU-9006925)
Irs-mediated signalling
(R-MMU-112399)
Irs-related events triggered by igf1r
(R-MMU-2428928)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Negative regulation of fgfr4 signaling
(R-MMU-5654733)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Phospholipase c-mediated cascade; fgfr4
(R-MMU-5654228)
Pi-3k cascade:fgfr4
(R-MMU-5654720)
Pi3k cascade
(R-MMU-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Raf/map kinase cascade
(R-MMU-5673001)
Shc-mediated cascade:fgfr4
(R-MMU-5654719)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-MMU-2404192)
Signal transduction
(R-MMU-162582)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Growth factor activity
(GO:0008083)
Heart development
(GO:0007507)
Negative regulation of bile acid biosynthetic process
(GO:0070858)
Negative regulation of gene expression
(GO:0010629)
Neural crest cell migration
(GO:0001755)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of glucose import
(GO:0046326)
Positive regulation of jnk cascade
(GO:0046330)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Regulation of cell migration
(GO:0030334)
Response to bacterium
(GO:0009617)

Other Information

Proteins

Fibroblast growth factor 15

Genular Protein ID: 742667213

Symbol: FGF15_MOUSE

Name: Fibroblast growth factor 15

UniProtKB Accession Codes:

O35622

Database IDs:

Citations:

PubMed ID: 9310317

Title: A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1.

PubMed ID: 9310317

DOI: 10.1242/dev.124.17.3221

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16213224

Title: Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.

PubMed ID: 16213224

DOI: 10.1016/j.cmet.2005.09.001

PubMed ID: 23747249

Title: Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.

PubMed ID: 23747249

DOI: 10.1016/j.cmet.2013.04.007

Sequence Information:

Length: 218
Mass: 25236
Checksum: A96B0D771FE125A5
Sequence:

MARKWNGRAV ARALVLATLW LAVSGRPLAQ QSQSVSDEDP LFLYGWGKIT RLQYLYSAGP 
YVSNCFLRIR SDGSVDCEED QNERNLLEFR AVALKTIAIK DVSSVRYLCM SADGKIYGLI 
RYSEEDCTFR EEMDCLGYNQ YRSMKHHLHI IFIQAKPREQ LQDQKPSNFI PVFHRSFFET 
GDQLRSKMFS LPLESDSMDP FRMVEDVDHL VKSPSFQK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgf15

Associated with

Other Information

A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. PubMed ID: 9310317

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334