Genular: Defining Cellular Identity and Function

Details for: Fgf2

Gene ID: 14173

Symbol: Fgf2

Ensembl ID: ENSMUSG00000037225

Description: fibroblast growth factor 2

Associated with

Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Downstream signaling of activated fgfr3
(R-MMU-5654708)
Downstream signaling of activated fgfr4
(R-MMU-5654716)
Extracellular matrix organization
(R-MMU-1474244)
Fgfr1 ligand binding and activation
(R-MMU-190242)
Fgfr1b ligand binding and activation
(R-MMU-190370)
Fgfr1c ligand binding and activation
(R-MMU-190373)
Fgfr2 ligand binding and activation
(R-MMU-190241)
Fgfr2b ligand binding and activation
(R-MMU-190377)
Fgfr2c ligand binding and activation
(R-MMU-190375)
Fgfr3 ligand binding and activation
(R-MMU-190239)
Fgfr3c ligand binding and activation
(R-MMU-190372)
Fgfr4 ligand binding and activation
(R-MMU-190322)
Fgfrl1 modulation of fgfr1 signaling
(R-MMU-5658623)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Frs-mediated fgfr3 signaling
(R-MMU-5654706)
Frs-mediated fgfr4 signaling
(R-MMU-5654712)
Igf1r signaling cascade
(R-MMU-2428924)
Insulin receptor signalling cascade
(R-MMU-74751)
Intracellular signaling by second messengers
(R-MMU-9006925)
Irs-mediated signalling
(R-MMU-112399)
Irs-related events triggered by igf1r
(R-MMU-2428928)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Negative regulation of fgfr1 signaling
(R-MMU-5654726)
Negative regulation of fgfr2 signaling
(R-MMU-5654727)
Negative regulation of fgfr3 signaling
(R-MMU-5654732)
Negative regulation of fgfr4 signaling
(R-MMU-5654733)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Non-integrin membrane-ecm interactions
(R-MMU-3000171)
Phospholipase c-mediated cascade: fgfr1
(R-MMU-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-MMU-5654221)
Phospholipase c-mediated cascade; fgfr3
(R-MMU-5654227)
Phospholipase c-mediated cascade; fgfr4
(R-MMU-5654228)
Pi-3k cascade:fgfr1
(R-MMU-5654689)
Pi-3k cascade:fgfr2
(R-MMU-5654695)
Pi-3k cascade:fgfr3
(R-MMU-5654710)
Pi-3k cascade:fgfr4
(R-MMU-5654720)
Pi3k cascade
(R-MMU-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Raf/map kinase cascade
(R-MMU-5673001)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Shc-mediated cascade:fgfr3
(R-MMU-5654704)
Shc-mediated cascade:fgfr4
(R-MMU-5654719)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by fgfr4
(R-MMU-5654743)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-MMU-2404192)
Signal transduction
(R-MMU-162582)
Syndecan interactions
(R-MMU-3000170)
Angiogenesis
(GO:0001525)
Animal organ morphogenesis
(GO:0009887)
Branching involved in ureteric bud morphogenesis
(GO:0001658)
Cell migration involved in sprouting angiogenesis
(GO:0002042)
Cell population proliferation
(GO:0008283)
Chemoattractant activity
(GO:0042056)
Chemokine binding
(GO:0019956)
Cytokine activity
(GO:0005125)
Embryo development ending in birth or egg hatching
(GO:0009792)
Endothelial cell proliferation
(GO:0001935)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Glial cell differentiation
(GO:0010001)
Growth factor activity
(GO:0008083)
Growth factor dependent regulation of skeletal muscle satellite cell proliferation
(GO:0014843)
Heparin binding
(GO:0008201)
Identical protein binding
(GO:0042802)
Integrin binding
(GO:0005178)
Multicellular organism development
(GO:0007275)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of fibroblast migration
(GO:0010764)
Neuroblast proliferation
(GO:0007405)
Nuclear receptor coactivator activity
(GO:0030374)
Organ induction
(GO:0001759)
Osteoblast differentiation
(GO:0001649)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of endothelial cell migration
(GO:0010595)
Positive regulation of endothelial cell proliferation
(GO:0001938)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of neuroblast proliferation
(GO:0002052)
Positive regulation of protein phosphorylation
(GO:0001934)
Protein binding
(GO:0005515)
Receptor-receptor interaction
(GO:0090722)
Substantia nigra development
(GO:0021762)
Transcription by rna polymerase ii
(GO:0006366)

Other Information

Proteins

Fibroblast growth factor 2

Genular Protein ID: 1479951413

Symbol: FGF2_MOUSE

Name: Fibroblast growth factor 2

UniProtKB Accession Codes:

P15655

Database IDs:

Citations:

PubMed ID: 2318343

Title: Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis.

PubMed ID: 2318343

DOI: 10.1016/0012-1606(90)90211-z

PubMed ID: 9178765

Title: Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis.

PubMed ID: 9178765

DOI: 10.1038/sj.onc.1201117

PubMed ID: 20851768

Title: Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.

PubMed ID: 20851768

DOI: 10.1016/j.mcn.2010.09.003

PubMed ID: 28323137

Title: Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.

PubMed ID: 28323137

DOI: 10.1016/j.joca.2017.03.010

Sequence Information:

Length: 154
Mass: 17153
Checksum: 689F677416274388
Sequence:

MAASGITSLP ALPEDGGAAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHVK 
LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTEEC FFFERLESNN YNTYRSRKYS 
SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgf2

Associated with

Other Information

Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. PubMed ID: 2318343

Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis. PubMed ID: 9178765

Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors. PubMed ID: 20851768

Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency. PubMed ID: 28323137

Database document:

PubMed ID: 2318343

PubMed ID: 9178765

PubMed ID: 20851768

PubMed ID: 28323137