Genular: Defining Cellular Identity and Function

Details for: Fgf5

Gene ID: 14176

Symbol: Fgf5

Ensembl ID: ENSMUSG00000029337

Description: fibroblast growth factor 5

Associated with

Downstream signaling of activated fgfr1
(R-MMU-5654687)
Downstream signaling of activated fgfr2
(R-MMU-5654696)
Downstream signaling of activated fgfr3
(R-MMU-5654708)
Fgfr1 ligand binding and activation
(R-MMU-190242)
Fgfr1c ligand binding and activation
(R-MMU-190373)
Fgfr2 ligand binding and activation
(R-MMU-190241)
Fgfr2c ligand binding and activation
(R-MMU-190375)
Fgfr3 ligand binding and activation
(R-MMU-190239)
Fgfr3c ligand binding and activation
(R-MMU-190372)
Fgfrl1 modulation of fgfr1 signaling
(R-MMU-5658623)
Frs-mediated fgfr1 signaling
(R-MMU-5654693)
Frs-mediated fgfr2 signaling
(R-MMU-5654700)
Frs-mediated fgfr3 signaling
(R-MMU-5654706)
Igf1r signaling cascade
(R-MMU-2428924)
Insulin receptor signalling cascade
(R-MMU-74751)
Intracellular signaling by second messengers
(R-MMU-9006925)
Irs-mediated signalling
(R-MMU-112399)
Irs-related events triggered by igf1r
(R-MMU-2428928)
Mapk1/mapk3 signaling
(R-MMU-5684996)
Mapk family signaling cascades
(R-MMU-5683057)
Negative regulation of fgfr1 signaling
(R-MMU-5654726)
Negative regulation of fgfr2 signaling
(R-MMU-5654727)
Negative regulation of fgfr3 signaling
(R-MMU-5654732)
Negative regulation of the pi3k/akt network
(R-MMU-199418)
Phospholipase c-mediated cascade: fgfr1
(R-MMU-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-MMU-5654221)
Phospholipase c-mediated cascade; fgfr3
(R-MMU-5654227)
Pi-3k cascade:fgfr1
(R-MMU-5654689)
Pi-3k cascade:fgfr2
(R-MMU-5654695)
Pi-3k cascade:fgfr3
(R-MMU-5654710)
Pi3k cascade
(R-MMU-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-MMU-6811558)
Pip3 activates akt signaling
(R-MMU-1257604)
Raf/map kinase cascade
(R-MMU-5673001)
Shc-mediated cascade:fgfr1
(R-MMU-5654688)
Shc-mediated cascade:fgfr2
(R-MMU-5654699)
Shc-mediated cascade:fgfr3
(R-MMU-5654704)
Signaling by fgfr
(R-MMU-190236)
Signaling by fgfr1
(R-MMU-5654736)
Signaling by fgfr2
(R-MMU-5654738)
Signaling by fgfr3
(R-MMU-5654741)
Signaling by insulin receptor
(R-MMU-74752)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-MMU-2404192)
Signal transduction
(R-MMU-162582)
Animal organ morphogenesis
(GO:0009887)
Cell differentiation
(GO:0030154)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Glial cell differentiation
(GO:0010001)
Growth factor activity
(GO:0008083)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of protein phosphorylation
(GO:0001934)
Regulation of cell migration
(GO:0030334)
Signal transduction involved in regulation of gene expression
(GO:0023019)

Other Information

Proteins

Fibroblast growth factor 5

Genular Protein ID: 2992596816

Symbol: FGF5_MOUSE

Name: Fibroblast growth factor 5

UniProtKB Accession Codes:

P15656 O88825

Database IDs:

Citations:

PubMed ID: 2318343

Title: Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis.

PubMed ID: 2318343

DOI: 10.1016/0012-1606(90)90211-z

PubMed ID: 1700424

Title: Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system.

PubMed ID: 1700424

DOI: 10.1073/pnas.87.20.8022

PubMed ID: 9786939

Title: An alternatively spliced fibroblast growth factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity.

PubMed ID: 9786939

DOI: 10.1074/jbc.273.44.29262

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 264
Mass: 29103
Checksum: F6A9C8153EE923D1
Sequence:

MSLSLLFLIF CSHLIHSAWA HGEKRLTPEG QPAPPRNPGD SSGSRGRSSA TFSSSSASSP 
VAASPGSQGS GSEHSSFQWS PSGRRTGSLY CRVGIGFHLQ IYPDGKVNGS HEASVLSILE 
IFAVSQGIVG IRGVFSNKFL AMSKKGKLHA SAKFTDDCKF RERFQENSYN TYASAIHRTE 
KTGREWYVAL NKRGKAKRGC SPRVKPQHVS THFLPRFKQS EQPELSFTVT VPEKKKPPVK 
PKVPLSQPRR SPSPVKYRLK FRFG

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fgf5

Associated with

Other Information

Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. PubMed ID: 2318343

Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system. PubMed ID: 1700424

An alternatively spliced fibroblast growth factor (FGF)-5 mRNA is abundant in brain and translates into a partial agonist/antagonist for FGF-5 neurotrophic activity. PubMed ID: 9786939